Bronchodilator therapy
Impact of bronchodilator therapy on exercise tolerance in COPD
... Abstract: Exercise tolerance is an important parameter in patients with COPD and a primary goal of treatment is to reduce dyspnea to facilitate physical activities and improve health-related quality of life. This review ...
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Effect of theophylline on exercise capacity in COPD patients treated with combination long-acting bronchodilator therapy: a pilot study
... Our study is the first to evaluate the effects of theophylline on exercise capacity in COPD patients already treated with combination long-acting inhaled bronchodilator therapy. We demonstrated that it is ...
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<p>An Evaluation Of Single And Dual Long-Acting Bronchodilator Therapy As Effective Interventions In Maintenance Therapy-Naïve Patients With COPD</p>
... maintenance therapy-naïve patients in two large phase III, randomized, double-blind, 24-week trials investigating the ef fi cacy of AB/ FF fi xed-dose combination versus either monotherapy or placebo in patients ...
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To evaluate the influence of inhaled bronchodilator therapy on spirometric test variables in obese and non-obese asthmatics
... Obesity acts as a risk factor for asthma through various mechanisms and it also reduces the spirometric variables as well as total lung capacity and functional residual capa[r] ...
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Randomized controlled trials and real-world observational studies in evaluating cardiovascular safety of inhaled bronchodilator therapy in COPD
... However, trial results need to be generalizable and suitable for extrapolation to a wider patient population to be clini- cally useful. There are several reasons why RCTs in COPD have often lacked external validity. COPD ...
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Eligibility of real-life patients with COPD for inclusion in trials of inhaled long-acting bronchodilator therapy
... This study combines an extensive range of RCT selection criteria with a large, representative COPD patient popula- tion to provide detailed information on eligibility of patients with COPD for participation in RCTs. The ...
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Combination bronchodilator therapy in the management of chronic obstructive pulmonary disease
... FDC therapy may be positioned in the treatment algorithm for ...maintenance therapy would be of interest, along with which groups of patients may benefit from this ...
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Response to bronchodilators in very preterm infants with evolving bronchopulmonary dysplasia
... Our study showed that approximately half of VLBW infants with evolving BPD in our contemporary cohort had a greater than 10% decrease in Rrs after bronchodilator therapy. It also appears that infants who ...
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Clinical efficacy of combinations of nebulised fluticasone, salbutamol and furosemide on lung function in premature calves with respiratory distress syndrome
... ual capacity (Yuksel and Greenough 1992). The res- piratory morbidity of preterm infants is associated with a high airway resistance (Yuksel et al. 1991) and reduced functional residual capacity (Yuksel and Greenough ...
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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
... mAb therapy in ...long-acting bronchodilator therapy, omalizumab decreased the level of free-circulating IgE, leading to improvements in patient quality of life, and decreased exacerbations with a ...
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Assessment of Bronchodilator Response in Various Spirometric Patterns
... Bronchodilator test is usually used in obstructive spirometric pattern, but nowadays there are some studies which have shown that bronchial reversibility and asthma may be accompanied by normal, restrictive or ...
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Bronchodilator efficacy and safety of indacaterol 150 µg once daily in patients with COPD: an analysis of pooled data
... efficacy, tolerability, and safety of indacaterol 150 µ g qd. Once-daily dosing with indacaterol 150 µ g provided a bronchodilator effect at 24 hours post-dose (trough FEV 1 ) that was 160 mL greater than with ...
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The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK
... This retrospective study aimed to establish the burden of disease for COPD patients treated with maintenance broncho- dilator monotherapy (either a LABA or LAMA) in the UK. To do so, we evaluated how many resources these ...
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<p>Patient-reported outcomes of dual bronchodilator fixed-dose combination versus bronchodilator monotherapy in individuals with COPD</p>
... dual therapy initiation leads to a higher persistence of therapy than ...prescribed therapy meets the person ’ s ...on therapy, compared to those who switched (both statistically signi fi ...
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A study of the relative bronchodilator responsiveness in smoker asthmatics
... Both the drugs were administered as aerosolized solutions via metered dose inhalers with spacer, which delivered fixed amount of drug per activation (puff). All the participants were asked to withhold their ...
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Evaluation of Bronchodilator and Anti-Anaphylactic Activity of Myrica sapida
... resulting in protective effects in bronchial asthma. The present findings reveal protection against egg albumin induced anaphylactic shock characterized by decrease in intensity and delay in the development of symptoms ...
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“INVESTIGATION OF THE BRONCHODILATOR ACTIVITY OF ABRUS PRECATORIUS” by Abraham Yeboah Mensah*, Audrey Serwah Bonsu, Theophilus Christian Fleischer, Ghana.
... possible bronchodilator activity by using various in vivo and in vitro models in guinea ...dose-dependent bronchodilator activity, thus justifying to some extent the traditional use of the plant Abrus ...
5
Bronchodilator treatment of stable COPD: long-acting anticholinergics
... et al. [33] showed that 12 weeks maintenance treatment with the combination of the LABA salmeterol and the SAAC ipratropium bromide was superior to salmeterol alone in terms of lung function and the incidence of ...
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Antispasmodic, bronchodilator, vasorelaxant and cardiosuppressant effects of Buxus papillosa
... 3 Concentration-dependent inhibitory effect of Buxus papillosa leaves extract fractions: a hexane BpL-H and b aqueous BpL-A on spontaneous and high K+-induced contractions in isolated ra[r] ...
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Bronchodilator action of inhaled nitric oxide in guinea pigs
... The effects of inhaling nitric oxide (NO) on airway mechanics were studied in anesthetized and mechanically ventilated guinea pigs. In animals without induced bronchoconstriction, breathing 300 ppm NO decreased baseline ...
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