Brown Norway (BN) rat
Anti-angiogenic Nanotherapy Inhibits Airway Remodeling and Hyper-responsiveness of Dust Mite Triggered Asthma in the Brown Norway Rat
... In this proof of concept study, the impact of anti-neovascular therapy was evaluated as a therapeutic regimen for asthma in a clinically relevant animal model. The temporal and spatial distribution of angiogenesis, ...
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Pulmonary effects of inhalation of spark-generated silver nanoparticles in Brown-Norway and Sprague–Dawley rats
... the Brown- Norway (BN) rat compared to a predominantly neutro- philic response in Sprague–Dawley (SD) ...2 rat strains. The BN rat is known to readily develop features of ...
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Pulmonary toxicity of instilled silver nanoparticles: Influence of size, coating and rat strain
... the BN rat to be ...the rat. We elected to study the Brown-Norway (BN) rat because this species is known to develop features of allergic asthma, namely lung eosinophilia ...
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Heavy metal exposure reverses genetic resistance to Chlamydia induced arthritis
... Many rheumatic diseases are thought to reflect an interplay of genetic susceptibility and environmental triggers, but there are few examples in which strong clues for the nature of these interacting elements are known. ...
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Transfer of allergic airway responses with antigen primed CD4+ but not CD8+ T cells in brown Norway rats
... postulated to play a central role in eliciting allergic inflammation; direct evidence of their involvement seems to be lacking. We hypothesized that CD4+ T cells have the potential to induce allergic responses to antigen ...
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Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat
... hypertensive rat (SHR) is the most widely studied animal model of essential ...of Brown-Norway rats (BN- Lx ...the BN- Lx strain onto the SHR background resulted in substantial ...
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Heme oxygenase-1-transduced bone marrow mesenchymal stem cells in reducing acute rejection and improving small bowel transplantation outcomes in rats
... male Brown Norway (BN) rats (RT-1 n ) and male Lewis rats (RT-1 l ) were purchased from Vital River Company (Beijing, ...Adult BN rats (180–200 g) and Lewis rats (200–220 g) were used as ...
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Effects of nebulized ketamine on allergen-induced airway hyperresponsiveness and inflammation in actively sensitized Brown-Norway rats
... a rat model of spinal cord injury [9], and the mortality of severely burnt rats is reduced ...(LPS)-induced rat model of of sepsis, by reducing NF- kappa B activity and TNF-alpha production [11], and ...
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Effect of the sensitization to Dermatophagoïdes pteronyssinus on the inflammatory response and bronchoconstrictive of brown Norway rats
... the brown Norway rat stimulated by intra tracheal instillation with the major proteins of Dermatophagoïdes pteronyssinus, an allergen responsible for the human sensitization when ...
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5 oxo ETE induces pulmonary eosinophilia in an integrin dependent manner in Brown Norway rats
... Immunocytochemistry. Slides were allowed to defrost and then stained with a monoclonal antibody to MBP by using the alkaline phosphate–antialkaline phosphate (APAAP) method as previously described (33). To prevent ...
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Novel dry powder preparations of whole inactivated influenza virus for nasal vaccination
... female Brown Norway rat (200g) was imaged in supine position following pipette aspiration delivery to the nostrils of 25 uL saline containing approximately 10 μCi of 99m Tc-SC for 30 minutes, with ...
366
Constant daily hypoxia leads to different degrees of pulmonary hypertension in two different rat strains
... Pulmonary diseases associated with diurnal hypoxe- mia are known to be associated with pulmonary hy- pertension in some patients. In this study we exam- ined the effects of daily hypoxia (10% oxygen; 8h/day for 14 days) ...
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Western diet-induced hepatic steatosis and alterations in the liver transcriptome in adult Brown-Norway rats
... WD rat feeding paradigms; and/or b) may be initiated by other factors that precede even- tual perturbations in local and systemic pro- inflammatory signalers with chronic WD ...
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3 Hydroxybutyrate co infused with noradrenaline decreases resulting plasma levels of noradrenaline in Wistar rats
... We used an infusion fluid buffered to pH 7.4 to minimize the negative effects of the infusion on the acid–base equilibrium of the rat. The noradrenaline solution was prepared freshly for each rat ...
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Behavioural Differences in Brown Norway and Wild Type Rats Maintained in Standard or Enriched Environment in Response to Novelty in a Familiarised Environment
... (Brown Norway) responded similarly to WWCPS rats immediately after the change, but their increased activity in that section of the experimental cage was not subject to habituation, ...
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A Combinatorial Note for Harmonic Tensors
... The annihilator of the space V ⊗n /V ⊗n Bn of dual partially harmonic tensors of f f valence f in the algebra Bn /Bn is the principal ideal Xm1 Bn ... Acknowledgments The author express[r] ...
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A selection of Safaitic inscriptions from the Mafraq Antiquities Office and Museum
... s¹ʿd bn ḥny bn ʿbd bn ṣʿd bn ʿbd bn ʿḏ bn s²rb bn ġlmt w wgd s¹fr ʾs²yʿ -h f ngʿ w rʿy h- ḍʾn f h lt ġnyt l- ḏ rʿy w mḥlt l- ḏ yʿwr h- s¹fr ‘By S¹ʿd son of Ḥny son of ʿbd ...
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Modulation of intracellular ATP influences seizure activity via the activity dependent release of adenosine
... Comparison of seizure related amino acid release in human epileptic hippocampus versus a chronic, kainate rat model of hippocampal epilepsy.. and Brown, B.G.[r] ...
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Amino acid effects in the feline central nervous system
... Published results of the relative effects in vitro of a series of GABA analogues on rat superior cervical ganglion neurones Bowery, Collins, Hudson and Neal, 1978; Bowery and Brown, 1974[r] ...
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Effect of Diet and Cold Exposure on Norepinephrine Turnover in Brown Adipose Tissue of the Rat
... interscapular brown adipose tissue (IBAT) after preliminary experiments validated the use of NE turnover techniques in IBAT. Acute exposure to 4°C increased NE turnover in IBAT 4- to 12-fold compared with ambient ...
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