C-C motif ligand
Plasma levels of monokine induced by interferon-gamma/chemokine (C-X-X motif) ligand 9, thymus and activation-regulated chemokine/chemokine (C-C motif) ligand 17 in children with Kawasaki disease
... (WBC), C-reactive protein (CRP) and erythrocyte sedimentation rate ...(C-X-C motif ) ligand 9 (MIG/CXCL9) and thymus and activation-regulated che- mokine/Chemokine (C-C ...
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Diverse activation of microglia by chemokine (C-C motif) ligand 2 overexpression in brain
... (C-C motif ) ligand 2 (CCL2) protein (also known as macrophage chemoattractant protein 1, or MCP-1) is well-recognized for its ability to mediate macrophage recruitment and migration to sites ...
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Chemokine (C-C motif) Ligand 2 is a potential biomarker of inflammation & physical fitness in obese children: a cross-sectional study
... As CCL2 levels are elevated in obesity and is associated with inflammation and in- sulin resistance, and as exercise lowers CCL2 levels, the aim of this study was to test the hypothesis [r] ...
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Original article - Common transcriptional programs and the role of chemokine (C-C motif) ligand 20 (CCL20) in cell migration of cholangiocarcinoma
... suspended in a FBS free-RPMI-1640 and plated inside the Transwell insert (Corning In- corporated, NY). The lower chamber contain- ing a RPMI-1640 supplemented with 5 % FBS or 5 % FBS with recombinant CCL20 (rCCL20, ...
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Inflammatory mediator release from primary rhesus microglia in response to Borrelia burgdorferi results from the activation of several receptors and pathways
... (C-C) motif ligand 2 (CCL2), chemokine (C-X-C) motif ligand 8 (CXCL8), and several others, secreted both by resident cells as well as incoming cells of the immune ...
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Chemokine-mediated inflammation in the degenerating retina is coordinated by Müller cells, activated microglia, and retinal pigment epithelium
... degeneration; C: choroid; Ccl12: Chemokine (C-C motif) ligand 12; Ccl2: Chemokine (C-C motif) ligand 2; Ccl20: Chemokine (C-C motif) ...
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Cells of the synovium in rheumatoid arthritis Synovial fibroblasts
... TLR2 ligand. Among these chemokines, C-X-C motif ligand (CXCL)2 (gro-2) and C-C motif ligand (CCL)8 (monocyte chemoattractant protein [MCP]-2) probably ...
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Systemic inflammatory response syndrome in a patient diagnosed with high grade inflammatory triple negative breast cancer: a case report of a potentially rare paraneoplastic syndrome
... (C–C motif ) ligand 2/monocyte chemotactic protein 1; CCL3/MIP1A: chemokine (C–C motif ) ligand 3/macrophage inflammatory protein 1‑alpha; CCL5/RANTES: chemokine ...
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Synovial fluid monocyte/macrophage subsets and their correlation to patient reported outcomes in osteoarthritic patients: a cohort study
... Abbreviations ADL: Activity of daily living; BMI: Body mass index; CCL2: Chemokine C-C motif ligand 2; CI: Confidence intervals; CX3CL1: Chemokine C-X3-C motif ligand 1; HLA-DR: Human le[r] ...
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Interleukin 17A promotes functional activation of systemic sclerosis patient derived dermal vascular smooth muscle cells by extracellular regulated protein kinases signalling pathway
... (C-C motif) ligand 20; CXCR-4: chemokine (C-X-C motif) receptor 4; DMEM: Dulbecco ’ s modified Eagle ’ s medium; DMSO: dimethyl sulfoxide; dSSc: diffuse cutaneous SSc; ...
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Metformin improves the angiogenic potential of human CD34+ cells co-incident with downregulating CXCL10 and TIMP1 gene expression and increasing VEGFA under hyperglycemia and hypoxia within a therapeutic window for myocardial infarction
... (C–C motif ) ligand (number); CM: conditioned medium; CVD: cardiovascular disease; CXCL10: chemokine (C–X–C motif ) ligand 10; DM: diabetes mellitus; EPCAM: ...
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<p>Cancer-Derived Transforming Growth Factor-β Modulates Tumor-Associated Macrophages in Ampullary Cancer</p>
... Notes: (A) THP-1 cells are activated using PMA for 3 days and then treated with conditioned medium from different cells for 3 days. The mRNA is purified, and the expression of macrophage-associated cytokines (OPN, IL-10, ...
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Soluble Siglec 9 suppresses arthritis in a collagen induced arthritis mouse model and inhibits M1 activation of RAW264 7 macrophages
... (C-C motif) ligand 2; CCR2, C-C chemokine receptor type 2; CFA, complete Freund ’ s adjuvant; CIA, collagen-induced arthritis; DMARD, disease-modifying antirheumatic drug; ELISA, ...
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Resistin upregulates chemokine production by fibroblast like synoviocytes from patients with rheumatoid arthritis
... (C-X-C motif) ligand (CXCL) 8, chemokine (C-C motif) ligand (CCL) 2, interleukin (IL)- 1 β , IL-6 and IL-32 in culture supernatants were measured by enzyme-linked ...
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Inflammation in epileptogenesis after traumatic brain injury
... CCL3: Chemokine (C-C Motif) ligand 3; CCL6: Chemokine (C-C Motif) ligand 6; CNS: Central nervous system; COX-2: Cyclooxygenase-2; CSF: Cerebrospinal fluid; CXCL8: Chemokine (C-X-C motif)[r] ...
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Dual effects of noradrenaline on astroglial production of chemokines and pro-inflammatory mediators
... the C-C chemokine receptor type 2 (CCR2) with CCL2, such as CCL6/C10, chemokine (C-C motif ) ligand 7 (CCL7)/monocyte chemotactic protein-3 (MCP-3) and chemokine ...
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Therapeutic potential of products derived from mesenchymal stem/stromal cells in pulmonary disease
... The MSC-derived secretome is released into CM in vitro [19–22, 32, 35–41]. MSCs respond to environmental changes and stress signals from injured tissues by secret- ing a myriad of soluble factors (Table 1); for instance, ...
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Adenovirus mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients
... PBMCs from pre, at week 5, and at week 9 after treatment initiation were analyzed by flow cytometry. The cells were thawed, washed with phosphate-buffered saline (PBS) and incubated with FcR blocking reagent (Miltenyi ...
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Cancer metastasis: enactment of the script for human reproductive drama
... CXCR4/CYCL12: C–X–C motif chemokine receptor 4/C–X–C Motif Chemokine Ligand 12; DNMT/TET: DNA methyltransferase/ten-eleven translocation methylcytosine dioxygenase; ...
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Increased CCL19 and CCL21 levels promote fibroblast ossification in ankylosing spondylitis hip ligament tissue
... We first investigated the expression of CCL19/CCL21 in AS and OA hip LT via real-time PCR and IHC. RT-PCR analysis revealed significantly increased transcriptional expression levels of CCL19/CCL21 (Figure 1A) in AS LT ...
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