• No results found

C2C12 cell

MiR-696 Regulates C2C12 Cell Proliferation and Differentiation by Targeting CNTFRα

MiR-696 Regulates C2C12 Cell Proliferation and Differentiation by Targeting CNTFRα

... During C2C12 cell proliferation, CNTFRα mRNA and protein level rose during cell confluence from 50% to ...50% cell confluence, the protein expression decreased (Figure 4D and ...during ...

13

Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines

Amygdalin isolated from Semen Persicae (Tao Ren) extracts induces the expression of follistatin in HepG2 and C2C12 cell lines

... myostatin [10-13], regulating cell proliferation, cell differen- tiation, inflammatory responses, and embryogenesis [11,14-16]. Follistatin has been recently evaluated as a treat- ment for fibrotic diseases ...

8

Proliferative effect of Hachimijiogan, a Japanese herbal medicine, in C2C12 skeletal muscle cells

Proliferative effect of Hachimijiogan, a Japanese herbal medicine, in C2C12 skeletal muscle cells

... in C2C12 cells. C2C12 cells were exposed to the indicated concentrations of hJg for the indicated ...hJg-induced C2C12 cell proliferation. C2C12 cells were pretreated ...

7

Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation

Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation

... Micropatterned C2C12 myotubes develop more sarcomeres than those grown on other substrates In this study, we compared C2C12 myotubes cultured on three different ...predominant cell culture methods ...

10

Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice

Telmisartan ameliorates insulin sensitivity by activating the AMPK/SIRT1 pathway in skeletal muscle of obese db/db mice

... the C2C12 model has limitations in comparison to freshly prepared frozen skeletal muscle cells [23]: C2C12 cells were originally obtained by Yaffe and Saxel through serial passage of myo- blasts cultured ...

9

Plastic Additives Decrease Agrin Induced Acetylcholine Receptor Clusters and Myotube Formation in C2C12 Skeletal Muscle Cell Culture

Plastic Additives Decrease Agrin Induced Acetylcholine Receptor Clusters and Myotube Formation in C2C12 Skeletal Muscle Cell Culture

... the C2C12 cell culture model to examine how exposure to BPA or DEHP affects two aspects of skeletal muscle development, the fusion of myob- lasts into myotubes and agrin-induced clustering of acetylcholine ...

11

Prion Infection of Muscle Cells In Vitro

Prion Infection of Muscle Cells In Vitro

... scrapie-infected C2C12 myoblast and myotube lysates to cause prion disease in mice was not due to residual scrapie inoculum (Table ...2). C2C12 myoblasts that were not infected with the 22L scrapie agent ...

10

From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and Disease

From Nutrient to MicroRNA: a Novel Insight into Cell Signaling Involved in Skeletal Muscle Development and Disease

... on C2C12 cell differentiation relies on Ser-307 phosphorylation of insulin receptor substrate 1 (IRS1) by mTORC1 and subsequent suppression of PI3K/Akt signaling (Figure 1) ...

15

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival

... from C2C12 cells (source of ERK1/2 acting as “prey”), which were prepared using a lysis buffer lacking ionic detergents (see Materials and Methods for ...Whole cell extracts from C2C12 cells treated ...

59

  PHARMACOLOGICAL EVALUATION OF HERBAL EXTRACTS FOR THEIR INVITRO HYPOGLYCEMIC ACTIVITY
 

  PHARMACOLOGICAL EVALUATION OF HERBAL EXTRACTS FOR THEIR INVITRO HYPOGLYCEMIC ACTIVITY  

... in C2C12 cell lines has showed highest sensitization potential to that of other ...HepG2 Cell lines the significant insulin mimetic activity was observed in APKJ004 ...(i.e., C2C12 cell ...

7

A fractionation method to identify qauntitative changes in protein expression mediated by IGF-1 on the proteome of murine C2C12 myoblasts

A fractionation method to identify qauntitative changes in protein expression mediated by IGF-1 on the proteome of murine C2C12 myoblasts

... are cell death or loss or other ...different C2C12 cell preparations were stimulated with IGF-1 (100 ng/ml) for up to 8 hours, fractionated using batch ion-exchange, separated by 2D electrophoresis, ...

18

An Innovative Strategy for the Fabrication of Functional Cell Sheets Using an Electroactive Conducting Polymer

An Innovative Strategy for the Fabrication of Functional Cell Sheets Using an Electroactive Conducting Polymer

... BMP2-immobilized C2C12 cell sheets without using an artificial ...these cell sheets were capable of conjugating BMP2 at bio- logically relevant levels via biotin-streptavidin inter- ...incubated ...

9

Original Article Comparative Analysis of Paired- and Homeodomain-specific Roles in PAX3-FKHR Oncogenesis

Original Article Comparative Analysis of Paired- and Homeodomain-specific Roles in PAX3-FKHR Oncogenesis

... similar cell culture and animal models ...expressing C2C12 cells developed benign and non-invasive tumors that regressed within a ...on cell proliferation ...

14

Anti-fatigue activity of a mixture of seahorse (Hippocampus abdominalis) hydrolysate and red ginseng

Anti-fatigue activity of a mixture of seahorse (Hippocampus abdominalis) hydrolysate and red ginseng

... Exercise-induced oxidative stress can cause the in- creased muscle fatigability. Thus, antioxidants can de- crease the oxidative stress and improve the physiological condition (You et al. 2011). Some reports showed that ...

8

miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation

miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation

... 450a-1, a non-myogenic miRNA which does not have overlapping predicted targets with miR-1/206. Luciferase quantification showed that this miRNA did not cross- react with the selected SR 3′ UTRs or with 3′ UTRs car- rying ...

12

Index Catalog // Carolina Digital Repository

Index Catalog // Carolina Digital Repository

... Methods: C2C12 myogenic cells were treated or untreated with BMP-2 alone or in combination with glycanated, partially glycanated or de-glycanated BGN, and the effects on BMP signaling and function were assessed by ...

118

3,4-DHPEA-EA Peracetylated (3,4-DHPEA-EA(P)) Attenuates H 2O -Mediated Cytotoxicity in C2C12 Myocytes via Inactivation of p-JNK/p-c-Jun Signaling Pathway

3,4-DHPEA-EA Peracetylated (3,4-DHPEA-EA(P)) Attenuates H 2O -Mediated Cytotoxicity in C2C12 Myocytes via Inactivation of p-JNK/p-c-Jun Signaling Pathway

... in C2C12 cells, as it is able to reduce intracellular levels of ROS resulting in inhibition of cell death and atrophy, conditions observed under increased oxidative ...

13

Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling

Clenbuterol Induces Cell Cycle Arrest in C2C12 Myoblasts by Delaying p27 Degradation through β-arrestin 2 Signaling

... on cell proliferation ...[30]. C2C12 are murine myoblast derived from satellite cells and cycling myoblasts are comparable to activated satellite cells in muscle fiber ...of C2C12 myoblasts in ...

10

A novel in vitro model for the assessment of postnatal myonuclear accretion

A novel in vitro model for the assessment of postnatal myonuclear accretion

... present in one LV-floxed-Luc myotube. We show that in this model, IGF-I induces a profound increase in postna- tal myonuclear accretion. IGF-I is a well-established driver of muscle hypertrophy that has been associated ...

13

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

Chromatin-wide and transcriptome profiling integration uncovers p38α MAPK as a global regulator of skeletal muscle differentiation

... the cell cycle, differentiate and fuse to form new fibers (or repair damaged ones), or self-renew to replenish the satellite cell ...(satellite cell-derived pri- mary myoblasts or myoblast ...

15

Show all 10000 documents...

Related subjects