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CA1 hippocampal pyramidal cell

A Stereological Study on Hippocampal Subfields Following Administration of Methamphetamine in Male Mice

A Stereological Study on Hippocampal Subfields Following Administration of Methamphetamine in Male Mice

... the hippocampal CA1 and CA3 in adult male ...of hippocampal CA1 and CA3 pyramidal ...Golgi-stained hippocampal CA1 and CA3 pyramidal neurons ...of ...

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Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice

Hippocampal changes produced by overexpression of the human CHRNA5/A3/B4 gene cluster may underlie cognitive deficits rescued by nicotine in transgenic mice

... of pyramidal neurons, Tg CHRNA5/A3/B4 males were crossed with Thy1-YFP (Yellow Fluorescent Protein) heterozygous fe- males ...of CA1 pyramidal neurons was determined within a 50 × 50 μm 2 area in a ...

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Input source and strength influences overall firing phase of model hippocampal CA1 pyramidal cells during theta: Relevance to REM sleep reactivation and memory consolidation

Input source and strength influences overall firing phase of model hippocampal CA1 pyramidal cells during theta: Relevance to REM sleep reactivation and memory consolidation

... TA-dominated hippocampal cell responses during memory consolidation may underlie the shift in mean theta phase observed in REM replay (Poe et ...all hippocampal synapses involved in encoding familiar ...

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The Reflected-Shifted-Truncated-Gamma Distribution for Negatively Skewed Survival Data with Application to Pediatric Nephrotic Syndrome

The Reflected-Shifted-Truncated-Gamma Distribution for Negatively Skewed Survival Data with Application to Pediatric Nephrotic Syndrome

... on CA1 pyramidal neurons (Marino et ...the cell surface and thereby increased NMDA responses at CA1 ...at hippocampal CA1 synapse, M1 receptor activation depresses NMDAR ...

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Reduced Potassium Currents in Old Rat CA1 Hippocampal Neurons

Reduced Potassium Currents in Old Rat CA1 Hippocampal Neurons

... the CA1 area of the hippocampus ...resembled pyramidal neurons with cell bodies that were approximately 10 –20 ␮m in ...the cell size (soma and neurites) were not altered during ...

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Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats

Induction- and conditioning-protocol dependent involvement of NR2B-containing NMDA receptors in synaptic potentiation and contextual fear memory in the hippocampal CA1 region of rats

... Transverse hippocampal slices (300 μm in thick- ness) were rapidly ...the CA1 region. Whole-cell patch clamp recordings were made in CA1 pyramidal ...

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Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice

Specific cytoarchitectureal changes in hippocampal subareas in daDREAM mice

... a cell mean, and the neu- rons from each animal were averaged for an animal ...the pyramidal cells in CA1 was calculated by multiplying the mean number of spines of a given por- tion of dendrite by ...

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Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND)

Voxel-wise comparisons of cellular microstructure and diffusion-MRI in mouse hippocampus using 3D Bridging of Optically-clear histology with Neuroimaging Data (3D-BOND)

... of hippocampal landmarks was used to drive registration between upsampled dMRI data and the corresponding confocal ...The cell population in each MRI voxel was determined within hippocampal ...

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Voltage activated currents in hippocampal CA1 neurones

Voltage activated currents in hippocampal CA1 neurones

... a pyramidal shape and retained some of their proximal dendritic ...up pyramidal cells or they could be intemeurons or ...of hippocampal slices which have been stained with rhodamine labelled tetanus ...

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Measles Virus Spreads in Rat Hippocampal Neurons by Cell-to-Cell Contact and in a Polarized Fashion

Measles Virus Spreads in Rat Hippocampal Neurons by Cell-to-Cell Contact and in a Polarized Fashion

... rat hippocampal slices by using MV expressing green fluorescent ...infected hippocampal neurons and spread unidirectionally, in a retrograde manner, from CA1 to CA3 pyramidal cells and from ...

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Amyloid precursor protein modulates β-catenin degradation

Amyloid precursor protein modulates β-catenin degradation

... in hippocampal CA1 pyramidal cells from APP knockout ...knockout CA1 pyramidal cells, accumulation of β-catenin was associated with the upregulation of cyclin D1, a downstream target of ...

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Neurodegeneration After Cardiac Arrest: Cell Death Mechanisms and Methods of Neuroprotection

Neurodegeneration After Cardiac Arrest: Cell Death Mechanisms and Methods of Neuroprotection

... In hippocampal CA1 pyramidal neurons, these factors activate cell death via pathologic activity of calpains, the family of Ca 2+ -dependent proteases, and calpain inhibition protects against ...

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High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte

High glutamate permeability and distal localization of Best1 channel in CA1 hippocampal astrocyte

... To estimate the degree of voltage error due to astro- cyte’s leaky membrane in our experimental condition, we next performed a dual patch-clamp recording onto CA1 astrocytes to observe the actual membrane voltage ...

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Interactions Between Hippocampal Areas CA3 and CA1 During Slow Wave Sleep

Interactions Between Hippocampal Areas CA3 and CA1 During Slow Wave Sleep

... and CA1 activity in slow-wave sleep ...in CA1 and ...both CA1 and CA3, with the relative increases in CA1 larger than those in ...in CA1 LFPs (ripples). Third, CA1 population ...

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Administering Copper Blocks CA1 Neuron Hyper Excitability in Rat Hippocampal Slices

Administering Copper Blocks CA1 Neuron Hyper Excitability in Rat Hippocampal Slices

... Figure 1. Top: The recordings show the mean FP voltage responses obtained from pyramidal CA1 neurons in rat hippocam- pal slices (n = 15) using penicillin G as an epileptic agent. The responses were ...

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Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia

Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia

... Delayed hippocampal damage is observed 3 to 7 days after the insult in CA1 pyramidal neurons (Kirino, 1982), suggesting that mechanisms that develop slowly after ischemia have an important role in ...

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A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction

A protein phosphatase 2A deficit in the hippocampal CA1 area impairs memory extinction

... coronal hippocampal slices were prepared at 25-μm thickness using a freezing microtome (CM-1950, ...the hippocampal CA1 area, the slices were incubated in primary antibody overnight at 4 ...(#2038, ...

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Calclium-calmodulin regulation of TRPM2 currents

Calclium-calmodulin regulation of TRPM2 currents

... Several splice variants of TRPM2 have been discovered. The first splice variant TRPM2-­‐S (“short”) is missing everything beyond transmembrane segment 2 (4 transmembrane segments and the C-­‐terminal). It is commonly ...

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Synaptic transmission between CA3 and CA1 neurones in the guinea pig hippocampal slice

Synaptic transmission between CA3 and CA1 neurones in the guinea pig hippocampal slice

... ipsilateral CA1 region (the Schaffer collateral pathway) is the focus of attention for this study, it should be noted that efferents are also supplied to other ...and CA1 regions (via the ventral ...

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Protection of Hippocampal CA1 Neurons Against Ischemia/Reperfusion Injury by Exercise Preconditioning via Modulation of Bax/ Bcl-2 Ratio and Prevention of Caspase-3 Activation

Protection of Hippocampal CA1 Neurons Against Ischemia/Reperfusion Injury by Exercise Preconditioning via Modulation of Bax/ Bcl-2 Ratio and Prevention of Caspase-3 Activation

... the CA1 pyramidal neurons in hippocampus are particularly vulnerable to isch- emic insult; in fact, these neurons die 3-7 days after transient forebrain ischemia (Ouyang, Voloboueva, Xu, & Giffard, ...

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