Caffeic Acid Phenethyl Ester
Comparison of Two Components of Propolis: Caffeic Acid (CA) and Caffeic Acid Phenethyl Ester (CAPE) to Induce Apoptosis and Cell Cycle Arrest of Breast Cancer Cells MDA-MB-231
... Keywords: caffeic acid; caffeic acid phenethyl ester; CAPE; apotosis; cell cycle; proliferation; breast 41.. cancer; propolis.[r] ...
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Evaluation of PECAM-1 and p38 MAPK expressions in cerebellum tissue of rats treated with caffeic acid phenethyl ester: a biochemical and immunohistochemical study
... [35]. Caffeic acid phenethyl ester (CAPE) is a flavonoid-like compound that is the active component of propolis, which is obtained from honey bee hives and has been long- used in traditional ...
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<p>Caffeic acid phenethyl ester suppressed growth and metastasis of nasopharyngeal carcinoma cells by inactivating the NF-κB pathway</p>
... Caffeic acid phenethyl ester (CAPE) is the main polyphe- nol extracted from honeybee propolis and polyphenol and can directly bind to the signaling molecules involved in carcino- genesis and ...
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Caffeic acid phenethyl ester attenuates neuropathic pain by suppressing the p38/NF-κB signal pathway in microglia
... of caffeic acid phenethyl ester (CAPE), the main ingredient of propolis, in improving neuropathic pain via its inhibition on p38/NF-κB signal pathway in ...
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Effects of caffeic acid phenethyl ester on palatal mucosal defects and tooth extraction sockets
... and caffeic acid phenethyl ester (palatal mucosal defect treated with caffeic acid phenethyl ester [caffeic acid phenethyl ester, 10 ...
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Protective antioxidative effects of caffeic acid phenethyl ester (CAPE) in the thyroid and the liver are similar to those caused by melatonin
... Background: Whereas oxidative reactions occur in all tissues and organs, the thyroid constitutes such an organ, in which oxidative processes are indispensable for physiological functions. In turn, numerous metabolic ...
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Caffeic acid phenethyl ester modulates Helicobacter pylori induced nuclear factor kappa B and activator protein 1 expression in gastric epithelial cells
... unclear. Caffeic acid phenethyl ester (CAPE), an active component of propolis from honeybee hives (honeybee resin), has been reported to have anti-inflammatory, anti-carcinogenic and ...
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Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21 Cip1 and p27 Kip1
... with caffeic acid phenethyl ester (CAPE) suppressed cell survival and proliferation via induction of G1 or G2/M cell cycle arrest in LNCaP 104-R1, DU-145, 22Rv1, and C4–2 CRPC ...
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Caffeic acid phenethyl ester promotes haematopoietic stem/progenitor cell homing and engraftment
... Caffeic acid phenethyl ester (CAPE) is a propolis ex- tract obtained from honeybee hives and an ester analogue of caffeic ...
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Evaluation of Bioelement Levels in Rat Tissues in Organophosphate Insecticide (Malathion) Toxicity: Effects of Caffeic Acid Phenethyl Ester (CAPE)
... Caffeic acid phenethyl ester (CAPE) is the most important active component of propolis. Also CAPE structure is similar to the flavonoids, is equipped with two ring structures. Two hydroxyl ...
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Effect of caffeic acid phenethyl ester on bone formation in the expanded inter-premaxillary suture
... Background: Narrow maxilla is a common problem in orthodontics and dentofacial orthopedics. To solve this problem, a procedure called rapid maxillary expansion (RME) has been used. However, relapse tendency is a major ...
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Solvent Free Synthesis of Carboxylic Acids and Amide Analogs of CAPE (Caffeic Acid Phenethyl Ester) under Infrared Irradiation Conditions
... of caffeic acid phenethyl amides (CAPA) note that it can act as an antioxidant against lipid peroxidation [6] as well as a potential anti-inflammatory agent through inhibition of 5-lipoxygenase ...
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Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester–induced apoptosis in C6 glioma cells
... cells were washed with phosphate-buffered saline (PBS) plus zinc ion (1 mM) and suspended in lysis buffer (50 mM Tris, 5 mM EDTA, 150 mM NaCl, 1% NP-40, 0.5% deoxycholic acid, 1 mM sodium ortho- vanadate, 81 μg/ml ...
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Caffeic acid phenethyl ester suppresses androgen receptor signaling and stability via inhibition of phosphorylation on Ser81 and Ser213
... CAPE accelerates AR protein degradation by inhibiting CDK1 activity, AKT activity and the phosphorylation of AR To determine if CAPE affects AR stability, we treated LNCaP 104-S and LNCa[r] ...
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Ethanol extract of propolis and its constituent caffeic acid phenethyl ester inhibit breast cancer cells proliferation in inflammatory microenvironment by inhibiting TLR4 signal pathway and inducing apoptosis and autophagy
... Our results suggested that Chinese propolis and its major constituent – CAPE inhibited TLR4 signaling pathway molecules such as TLR4, MyD88, IRAK4, TRIF and NF- kB p65, which might be on[r] ...
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Roos, Thomas (2006): The polyphenols resveratrol and caffeic acid phenethyl ester: their influence on growth-related signaling pathways in vascular smooth muscle cells. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... The PDGF family consists of four different proteins, PDGF-A, PDGF-B, PDGF-C, and PDGF-D, encoded by four different genes. About thirty years ago, PDGF-A and PDGF-B, the classical PDGF chains, were discovered. PDGF-A ...
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Propolis changes the anticancer activity of temozolomide in U87MG human glioblastoma cell line
... Abbreviations AP: Alkaline phosphatase; BxPC-3: Human pancreatic cancer cell line; CAPE: Caffeic acid phenethyl ester; CI41: Human leukemia cell line; CNS: Central Nervous System; DMSO: [r] ...
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Ethanol extracted Cameroonian propolis exerts estrogenic effects and alleviates hot flushes in ovariectomized Wistar rats
... CAPE: Caffeic acid phenethyl ester; DMEM: Dulbecco ’ s modified eagle ’ s medium; E2V: Estradiol valerate; EC: Elemental compositions; EEP: Ethanolic extract of Cameroonian propolis; ER: ...
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Effect of reaction parameters on lipase-catalyzed synthesis of caffeic acid bornyl ester (CABE)
... most ester and transester synthesis (Yadav and Lathi, 2005; Pang et ...of caffeic acid phenethyl ester (CAPE) also displayed that Novozym 435 exhibited the highest activity compared to ...
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“A Review on Therapeutic Potential of Caffeic Acid and its Derivatives” by Dr.V.M.Mounnissamy, B. Priya, India.
... The phenethyl caffeate exhibited antibacterial activity against ...to ester, which showed strong antibacterial ...chain ester derivatives of caffeic acid were synthesized and their antibacterial ...
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