Caki-2
Original Article Synergistic effects of snail and quercetin on renal cell carcinoma Caki-2 by altering AKT/mTOR/ERK1/2 signaling pathways
... ccRCC Caki-2 cell line with either Snail shRNA or quercetin causes a significant reduc- tion in cell proliferation, a strong cell cycle arrest at G1/S phase with a concomitant induc- tion of ...
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Thyroid hormone – triiodothyronine – has contrary effect on proliferation of human proximal tubules cell line (HK2) and renal cancer cell lines (Caki-2, Caki-1) – role of E2F4, E2F5 and p107, p130
... It is known that proximal tubules proliferate slower than ccRCC derived cells [22], therefore HK2, Caki-2 and Caki- 1 proved to be a proper cellular model for investigation of differences in cell ...
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Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1
... lines Caki-2, Caki-2/DOX and ...of Caki-2 cells was increased by co-transfection with pGL3-ABCC1- WT and miR-210-3p inhibitor, and the luciferase activ- ity of ...
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Original Article Combination of metformin and valproic acid synergistically induces cell cycle arrest and apoptosis in clear cell renal cell carcinoma
... and caki-2 cell lines were evaluated by MTT ...and Caki-2 cells viability in a dose-dependent and time-dependent ...In Caki-2 cells, metformin combined with VPA had a synergistic ...
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Some certain properties of the generalized hypercubical functions
... RESEARCH Open Access Some certain properties of the generalized hypercubical functions Du?ko Leti?1, Nenad Caki?2, Branko Davidovi?3*, Ivana Berkovi?1 and Eleonora Desnica1 * Correspondence iwtbg@beot[.] ...
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<p>Suppressed OGT expression inhibits cell proliferation and modulates EGFR expression in renal cell carcinoma</p>
... and CAKI-2 cells were cultured in RMPI 1640 (Thermo Fisher Scientific), while HK-2 cells were cultured in Keratinocyte Medium (KM, ScienCell, Carlsbad, CA, ...
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Effect of perineoplasm perinephric adipose tissues on migration of clear cell renal cell carcinoma cells: a potential role of WNT signaling
... Figure 2: Waterfall plotting of percentage increase or decrease of perineoplasm PAT CMs that induced cell migration and ...A. Caki-2 cells were applied to the upper surface of a ...B. 2×10 4 ...
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Long noncoding RNA BX357664 regulates cell proliferation and epithelial-to-mesenchymal transition via inhibition of TGF- 1/ p38/HSP27 signaling in renal cell carcinoma
... the caki-1 and caki-2 were seeded in 6-well plates at 40% confluence on the day before ...infect caki-1 and caki-2 cells at a multiplicity of infection (MOI) of ...
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Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
... = 130 μg/ml). The inhibition of cell migration after treat- ment with HNE was very strong (> 90%) on SK-N-SH and strong (~ 70%) on LN229, but there was only a little effect on U87-MG glioblastoma cells, grade IV, ...
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Cripto-1 expression in patients with clear cell renal cell carcinoma is associated with poor disease outcome
... in Caki-2 cells, and the opposite effects were acquired when CR-1 was knocked down in Caki-1 and 786-O cells ...in Caki-2 Table 2 Cox regression analysis for overall survival and ...
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Notch signaling plays a crucial role in cancer stem-like cells maintaining stemness and mediating chemotaxis in renal cell carcinoma
... or Caki-1 cell lines have stem cell behav- ior, the soft agar colony formation assay, sphere- forming assay, invasion and migration by transwell assay, drug sensitivity by MTT assay and tumorigen- icity assay in ...
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Polydatin exerts anti-tumor effects against renal cell carcinoma cells via induction of caspase-dependent apoptosis and inhibition of the PI3K/Akt pathway
... and Caki-1 cells were seeded in six-well ...and caki-1 cells were treated with indicated doses of PD for 24 hours, and then subjected to invasion ...and caki-1 cells were treated with indicated doses ...
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miR-96 suppresses renal cell carcinoma invasion via downregulation of Ezrin expression
... Caki-1 and 786-O, which are human RCC cell lines with high and low metastatic potential, respectively, were pur- chased from the Type Culture Collection of the Chinese Academy of Sciences (Shanghai, China). ...
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Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion
... adding Caki-1 to the TNF-alpha stimulated HUVEC evoked a significantly diminished endothelial ICAM-1, VCAM-1 and E-selectin expression, compared to HUVEC not influenced by ...
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<p>miR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1</p>
... BALB/c mice (male, 16 – 20 g) were obtained from Vital River Laboratories (Beijing, China). All animal experiments were carried out according to the National Institutes of Health Guide for the Care and Use of Laboratory ...
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YM155 sensitizes TRAIL-induced apoptosis through cathepsin S-dependent down-regulation of Mcl-1 and NF-κB-mediated down-regulation of c-FLIP expression in human renal carcinoma Caki cells
... from Clonetics (San Diego, CA). The human skin fibroblast (HSF) was a gift from Dr. T.J. Lee (Yeungnam University, Korea). All cells were cultured in Dulbecco's Modified Eagle's Medium containing 10% fetal bovine serum, ...
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... First, we analyzed the expression levels of mature miRNAs in sunitinib-treated RCC specimens by PCR- based array analysis. Also, we reviewed our miRNA expression data of 10 sunitinib-naïve RCC specimens and 5 normal ...
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Panobinostat synergizes with bortezomib to induce endoplasmic reticulum stress and ubiquitinated protein accumulation in renal cancer cells
... mg/m 2 bortezomib twice a week with 20 mg of dexamethasone four times a week on weeks 1 and ...1, 2, and 4 with dexamethasone on the days of and after ...
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In vitro antitumor effects of AHR ligands aminoflavone (AFP 464) and benzothiazole (5F 203) in human renal carcinoma cells
... Aminoflavone (AF; NSC 686288, AFP 464, NSC710464) is a new anticancer agent undergoing phase II clinical evaluation. It has demonstrated antiproliferative effects in MCF-7 human breast cancer cells mediated by AhR. AF ...
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2′ (2 Thienylmethylidene) 2 hydroxybenzohydrazide
... The molecule is essentially planar, with an r.m.s. deviation of 0.0048 AÊ. An intermolecular OÐH O hydrogen bond is observed linking the hydroxyl H atom with the carbonyl group of an adjacent molecule. In addition, an ...
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