Calcium channel blockers (CCBs)
Synthesis and in-vitro screening of novel dihydropyrimidine derivatives as potential calcium channel blockers
... Calcium channel blockers (CCBs) are prescribed for the treatment of hypertension, angina and arrhythmia ...as calcium channel blocker [5,6], antitubercular [7], antitumor [4,8], ...
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A COMPLETE GUIDE ON THE PHARMACOLOGIC AND PHARMACOTHERAPEUTIC ASPECTS OF CALCIUM CHANNEL BLOCKERS: AN EXTENSIVE REVIEW
... second calcium channel blockers are associated with edema, reflux tachycardia, and cardio depressive action, whereas these adverse events are reduced in the newer drugs due to its high vascular ...
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Original Article Inhibition of a calcium channel blockers on human urethral scars in vitro and in vivo
... Although, CCBs have been researched for numerous fibrosis diseases, they have been rarely used to study urethral scars. The results of this study show that verapamil inhibited USFs proliferation and presented a dose- ...
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Impact of preadmission treatment with calcium channel blockers or beta blockers on short-term mortality after stroke: a nationwide cohort study
... Calcium channel blockers (CCBs) and beta blockers (BBs) are commonly used antihypertensive agents [7]. It has previously been established that elevated pread- mission blood pressure is ...
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Using Calcium Channel Blockers to treat: High Blood Pressure and Heart Disease
... Cochrane review focused specifically on calcium channel blockers both concluded that diuretics were better first options because they more effectively reduced cardiovascular problems. CCBs are very ...
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Antiplatelet Effect of Clopidogrel Can Be Reduced by Calcium Channel Blockers
... dihydropyridine calcium channel blockers ...receptor blockers were newly administered to the patients or dosed up for control of blood ...
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Comparative effect of angiotensin II type I receptor blockers and calcium channel blockers on laboratory parameters in hypertensive patients with type 2 diabetes
... receptor blockers (ARBs) are well established antihypertensive drugs that are frequently used as the first-line drug for ...[2]. Calcium channel blockers (CCBs) are also widely used first-line ...
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Original Article Mechanism of calcium channel blockers in relieving pathological pain of diabetic peripheral neuropathy in rats
... Abstract: Diabetic neuropathic pain (DNP) is complex and refractory. Commonly used calcium channel blockers (CCBs) can be divided into L type and T type. T type CCB mibefradil can alleviate DNP. ...
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EFFECTS OF SOME CALCIUM CHANNEL BLOCKERS AGAINSTS CCL4-INDUCED NEPHROTOXICITY IN ALBINO RATS
... in rats. This study is important because, CCBs are commonly used for the treatment of hypertention in many parts of the world, but have not been clinically known to be used for treatment of acute kidney injuries. ...
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Original Article Calcium channel blockers and risk of breast cancer: a meta-analysis
... Abstract: Purpose: Studies on the association between the use of calcium channel blockers (CCBs) and breast cancer risk have reported inconsistent results. We quantitatively evaluated this ...
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<p>Anticancer Effects of Antihypertensive L-Type Calcium Channel Blockers on Chemoresistant Lung Cancer Cells via Autophagy and Apoptosis</p>
... are calcium channel blockers (CCBs), thiazide diuretics (TD), angio- tensin-converting enzyme inhibitors (ACEi), angiotensin II receptor antagonists (ARBs), and beta blockers ...of ...
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Anti-Inflammatory Activity Of Calcium Channel Blockers
... This study suggests that possession of anti- inflammatory activities in CCBs reflects their similarity in action to NSAIMs. Inhibition of prostaglandin synthesis appears to be a logical approach to their mechanism of ...
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Role of Calcium Channel Blockers in Inducing Gingival Enlargement - A Cross Sectional Study
... The present study included 30 hypertensive subjects on calcium channel blockers and 30 healthy controls who were not on any of the drugs causing gingival enlargement. Written consent was obtained and ...
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Synthesis of Novel 1,4- Dihydropyridine Derivatives Bearing Biphenyl-2'-Tetrazole Substitution as Potential Dual Angiotensin II Receptors and Calcium Channel Blockers
... In the previous work, this strategy led to the design and synthesis of novel 4-[2 ΄ -(carboxylic acid)biphenyl-4-yl] imidazolyl-1,4-dihydropyridine-3,5-dicarboxylates as potential dual acting angiotensin II inhibitors ...
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Current concepts in combination therapy for the treatment of hypertension: combined calcium channel blockers and RAAS inhibitors
... of calcium antagonists and inhibitors of the renin-angiotensin-aldosterone system (RAAS) are efficacious and safe, and have been considered rational by both the JNC 7 and the 2007 European Society of Hypertension ...
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COMPUTER AIDED DESIGN OF SELECTIVE CALCIUM CHANNEL BLOCKERS: USING PHARMACOPHORE – BASED AND DOCKING SIMULATIONS
... N-type calcium channel blockers. Calcium Channel blockers is the molecular target responsible for the treatment of neuropathic and inflammatory ...of calcium ...
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Effects of Calcium Channel Blockers on Trypsinogen Activation and Severity of Cerulein-induced Acute Pancreatitis in Rats
... of calcium channel blockers such as 2-aminoethoxydiphenyl borate, dantrolene and verapamil were investigated in cerulein-induced acute pancreatitis in ...of calcium channel ...
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Effectiveness of Calcium Channel Blockers as Local Ointment Vs Lateral Sphincterotomy in the Treatment of Chronic Fissure in Ano
... these, calcium channel blockers (2% Diltiazem) as local ointments are used in this study because of its better healing rate and least side ...
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COMBINATION OF AQUEOUS EXTRACTS OF CURCUMA LONGA (TURMERIC) AND SOME CALCIUM CHANNEL BLOCKERS SYNERGISTICALLY IMPROVES CCL4-INDUCED HEPATOTOXICITY IN ALBINO RATS
... These calcium channel blockers act by preventing the influx of calcium ions into hepatocytes, examples are: verapamil, nifedipine, amlodipine and diltiazem ...
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Synthesis of Acetylated Dihydropyrimidine Analogues Under Solvent free Conditions and their Evaluation as Calcium Channel Blockers
... Calcium channel blockers are widely used for treating the disorders of cardiovascular ...used calcium channel blockers include nifedipine, verapamil ...of Calcium ...
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