calcium entry
Systems Modeling of Calcium Homeostasis and Mobilization in Platelets Mediated by Ip3 and Store-Operated Calcium Entry
... mediated calcium regulation was extended to include mechanisms for calcium influx from the extracellular ...cytosolic calcium responses to a transient stimulatory ...platelet calcium signaling ...
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Effect of thrombin on calcium homeostasis in chick embryonic heart cells Receptor operated calcium entry with inositol trisphosphate and a pertussis toxin sensitive G protein as second messengers
... intracellular calcium release, since it persisted after removal of external ...zero calcium was more transitory than in normal calcium and was potentiated by 10 mM ...of calcium across the ...
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The Potential Role of Store-Operated Calcium Entry (SOCE) Pathways in the Pathophysiology of Epilepsy and Migraine-Like Headaches in Patients with Neurocysticercosis
... store-operated calcium entry (SOCE) pathways are involved in the regulation of the intracellular ionic equilibrium and are determinants of the neuronal excitability ...
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FGF4 induces epithelial-mesenchymal transition by inducing store-operated calcium entry in lung adenocarcinoma
... Several fibroblast growth factor (FGF) isoforms act to stimulate epithelial- mesenchymal transition (EMT) during cancer progression. FGF4 and FGF7 are two ligands of FGF receptor 2 (FGFR2). Using two lung adenocarcinoma ...
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FGF2 promotes metastasis of uveal melanoma cells via store-operated calcium entry
... Abstract: Uveal melanoma (UM), the most common primary intraocular malignancy in adults, is highly metastatic and associated with dismal prognosis. Fibroblast growth factor 2 (FGF2) has been shown to induce cell ...
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Activation of the Endoplasmic Reticulum Calcium Sensor STIM1 and Store-Operated Calcium Entry by Rotavirus Requires NSP4 Viroporin Activity
... ER calcium stores and activation of plasma membrane (PM) calcium influx channels, ultimately causing a 2- to 4-fold elevation in cytoplasmic ...cytoplasmic calcium is abso- lutely required for virus ...
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Direct and indirect effects of calcium entry blocking agents on isovolumic left ventricular relaxation in conscious dogs
... intravenous calcium entry blockade either produced no significant change (diltiazem and verapamil) or shortened (nifedipine T1 - 18%, P less than ...
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Cch1 Mediates Calcium Entry in Cryptococcus neoformans and Is Essential in Low-Calcium Environments
... It may not be surprising that Cch1 might harbor some unique regulatory features, when one considers that four of the five subunits ( ␣ 2,  , ␦ , and ␥ ) that constitute voltage-gated Ca 2⫹ channels in higher eukaryotes ...
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RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry
... Indeed, RPGR and RPGRIP1 have been reported to co-localize in the connecting cilia of photoreceptors and centrosomes/basal bodies of differentiating cells [8, 18, 23, 24]. RPGRIP1L is also localized to the basal bodies ...
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Orai3 Surface Accumulation and Calcium Entry Evoked by Vascular Endothelial Growth Factor
... 35. McKeown L, Moss NK, Turner P, Li J, Heath N, Burke D, O’Regan D, Gilthorpe MS, Porter KE, Beech DJ. Platelet-derived growth factor main- tains stored calcium through a nonclustering Orai1 mechanism but evokes ...
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Na+/Ca2+ exchange mediated calcium entry in human lymphocytes
... Ca2+ entry and cytosolic Ca2+ (measured with fura- 2) were monitored in cells in which cytosolic Na+ was increased and/or the Na+ gradient was decreased by reduction of external Na+ ...Ca2+ entry following ...
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Activation of ERK1/2 by Store-Operated Calcium Entry in Rat Parotid Acinar Cells
... 2+ entry via ARC channels and SOCE are reciprocally ...2+ entry via ARC occurs at low receptor agonist concentration, and that higher concentrations of agonist activate SOCE and produce high sustained ...
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A critical role for STIM1 in filopodial calcium entry and axon guidance
... membrane entry from internal release from the stores ...2+ entry events only at near-plasma membrane ...2+ entry events generated within the filopodium independ- ently of Ca 2+ transients from the ...
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Excess NO stabilizes the luminal domain of STIM2 in a Cys-specific manner thereby regulating basal calcium homeostasis and store-operated calcium entry
... Because excess NO thermodynamically stabilizes wildtype STIM2 15-217 to a larger degree compared to Cys15Ser STIM2 15-217, it is likely that the loss of the Cys15 modifiable [r] ...
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Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis
... There is convincing evidence that Ca 2+ entry through SOCE channels differentially activates different down- stream signaling pathways. This is supported by our earl- ier studies showing contributions of ...
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Role of Dicer Enzyme in the Regulation of Store Operated Calcium Entry (SOCE) in CD4+ T Cells
... with calcium containing Fluo4 and Fluo3 (Invitrogen, Germany) for 30 minutes in a 37 °C incubator as described earlier ...intracellular calcium levels were measured by flow cytometry analysing 20,000 ...
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Activation of store operated calcium entry in airway smooth muscle cells: insight from a mathematical model
... 10. Moynihan B, Tolloczko B, Michoud MC, Tamaoka M, Ferraro P, et al. (2008) MAP kinases mediate interleukin-13 effects on calcium signaling in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol ...
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Activation of TRPV2 and BKCa channels by the LL-37 enantiomers stimulates calcium entry and migration of cancer cells
... siRNA (siCt) in presence and absence of LL-37. The mid panel displays compilation of results. Fura-2 fluorescence ratio is normalized against the basal level of each individual experiment. The dotted line shows the ...
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Polyamines mediate uncontrolled calcium entry and cell damage in rat heart in the calcium paradox
... studies. Calcium-free perfusion promptly (less than 5 min) decreased the levels of polyamines and the activity of their rate- regulating synthetic enzyme, ornithine decarboxylase (ODC), and calcium ...
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Responsiveness to progesterone and potassium channel blockers 4-aminopyridine, tetraethylammonium and free Ca(2+) contentration in spermatozoa of patients with oligozoospermia/leucocytospermia
... progesterone-induced calcium transient was undetectable and subsequent calcium entry was much smaller compared to normospermic ...a calcium signal to its site of action or by reduced or absent ...
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