Calcium – sensing receptor
Homology Modeling of the Calcium Sensing Receptor Extracellular Domain
... the calcium-sensing receptor, (allosteric agonist) which leads to a different structural configuration that is more sensitive to serum ...serum calcium levels; therefore, adverse effects ...
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Associations between single nucleotide polymorphisms in the calcium sensing receptor and chronic kidney disease-mineral and bone disorder in cats
... O'Seaghdha, C.M., Yang, Q., Glazer, N.L., Leak, T.S., Dehghan, A., Smith, A.V., Kao, W.H., Lohman, K., Hwang, S.J., Johnson, A.D., Hofman, A., Uitterlinden, A.G., Chen, Y.D., Brown, E.M., Siscovick, D.S., Harris, T.B., ...
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SINGLE NUCLEOTIDE POLYMORPHISMS OF CALCIUM SENSING RECEPTOR ENCODING GENE ASSOCIATED WITH CALCIUM KIDNEY STONE DISEASE IN BABYLON PROVINCE
... urine calcium levels, calcium supplements, certain foods, obesity, hyperparathyroidism, gout, some medications, and not drinking enough ...The calcium-sensing receptor (CASR) is a ...
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Extracellular calcium sensing receptor mediated signalling is involved in human vascular smooth muscle cell proliferation and apoptosis
... Abstract. Calcium-sensing receptor (CaSR) plays key role in vascular calcification in patients with chronic kidney disease (CKD). We investigated the role of CaSR in regulating smooth muscle cell ...
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Original Article The effects of calcium-sensing receptor (CASR) gene variants on colorectal cancer (CRC) risk and mortality: a systematic review and meta-analysis
... We searched literature from PubMed, Embase, Cochrane Library, and Web of Science databas- es with the terms: “calcium-sensing receptor”, “CASR”, “colorectal neoplasm”, “colorectal can- cer”, “CRC” ...
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Calcium sensing receptor mutations in familial benign hypercalcemia and neonatal hyperparathyroidism
... Familial benign hypercalcemia (FBH) and neonatal hyperparathyroidism (NHPT) are disorders of calcium homeostasis that are associated with missense mutations of the calcium-sensing receptor ...
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Calcium-sensing receptor gene (CASR) polymorphisms and CASR transcript level concerning dyslipidemia in hemodialysis patients: a cross-sectional study
... of calcium- sensing receptor gene (CASR) are predominantly asso- ciated with phenotypes of primary [4] and secondary hyperparathyroidism [5–8], and with idiopathic cal- cium nephrolithiasis [9, ...
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Quantitative assessment of the clinical susceptibility of calcium-sensing receptor polymorphisms in cancer patients
... (“Calcium-Sensing Receptor” OR “CASR”) AND (“can- cer” OR “malignancies” OR “neoplasms” OR “tumor” OR “carcinoma”) AND (“polymorphism” OR “variation” OR “variant” OR “single nucleotide polymorphism” ...
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Familial hypocalciuric hypercalcemia with a de novo heterozygous mutation of calcium-sensing receptor
... of calcium-sensing receptor (CASR) gene typically causes neonatal hyperparathyroidism (NHPT) with moderate hypercalcemia and hyperparathyroid bone ...
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Alterations in phosphorus, calcium and PTHrP contribute to defects in dental and dental alveolar bone formation in calcium sensing receptor deficient mice
... The calcium-sensing receptor (CaR; CASR – Mouse Genome Informatics) is a plasma membrane G-protein-coupled receptor that is activated by extracellular ...systemic calcium homeostasis, ...
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A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations
... Background: The role of mutations in the serine protease inhibitor Kazal type 1 (SPINK1) gene in chronic pancreatitis is still a matter of debate. Active SPINK1 is thought to antagonize activated trypsin. Cases of SPINK1 ...
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A novel mutation in the calcium sensing receptor gene in an Irish pedigree showing familial hypocalciuric hypercalcemia: a case report
... the calcium-sensing receptor (CaSR) gene in the majority of cases ...The calcium sensing receptor (CaSR) is a G-protein-coupled receptor of 1078 amino acids (AAs) with a ...
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The functional expression of extracellular calcium-sensing receptor in rat pulmonary artery smooth muscle cells
... Intracellular calcium, a secondary messenger, plays a key role in various physiological ...extracellular calcium can act as a first messenger through the calcium-sensing receptor (CaSR) ...
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Calcium sensing receptor activation increases cell cell adhesion and ß cell function
... extracellular calcium sensing receptor (CaR) plays a central role in maintaining systemic Ca 2+ -homeostasis by regulating the secretion of parathyroid hormone and urinary calcium ...
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A novel mutation in calcium-sensing receptor gene associated to hypercalcemia and hypercalciuria
... of calcium-sensing receptor (CaSR) gene, involved in PTH regulation as well as in renal calcium ...a Calcium/Creatinine ratio of ...ionized calcium levels were close to the upper ...
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Biological Function of Calcium-Sensing Receptor (CAS) and Its Coupling Calcium Signaling in Plants
... droughts tolerant due to excessive transpiration when grown under low soil moisture conditions [24]. In rice, the calcium-sensing receptor gene (OsCAS) is also closely associated with drought ...
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Expression of the calcium sensing receptor on human antral gastrin cells in culture
... extracellular calcium-sensing receptor on human antral gastrin cells was ...cell calcium-sensing ...the receptor immuno- stained all gastrin cells (but not mucin or somatostatin ...
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The calcium sensing receptor and insulin secretion : a role outside systemic control 15 years on
... extracellular calcium-sensing receptor (CaR; Brown et ...coupled receptor in the physiology and patho-physiology of systemic calcium regulation (extensively reviewed in Brown ...free ...
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Protein-induced satiation and the calcium-sensing receptor
... acid sensing by the calcium-sensing receptor: a general mechanism for coupling protein and calcium metabolism? Eur J Clin ...al. Calcium-sensing receptor is a ...
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The calcium sensing receptor regulates mammary gland parathyroid hormone–related protein production and calcium transport
... of calcium from mother to milk during lactation is poorly ...and calcium trans- port in mammary epithelial cells are regulated by extracellular calcium acting through the calcium- ...
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