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calcium signaling

Translating intracellular calcium signaling into models

Translating intracellular calcium signaling into models

... intracellular calcium has put theoreticians in an ideal position to derive models of intracellular calcium ...intracellular calcium modeling with a special emphasis on ...

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Mechanical regulation of calcium signaling of HL-60 on P-selectin under flow

Mechanical regulation of calcium signaling of HL-60 on P-selectin under flow

... Intracellular calcium bursting of adhered neutrophils is a key event for subsequent arresting firmly at and migrating into the injured ...cytoplasmic calcium signaling of the cells were modulated by ...

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Regionalized calcium signaling in zebrafish fertilization

Regionalized calcium signaling in zebrafish fertilization

... of calcium signaling at fertilization Fertilization-induced calcium signaling in zebrafish oocytes has been studied by fluorescence microscopy using a calcium sensitive fluorescent ...

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Challenging the dogma : reevaluating the role of astrocyte calcium signaling in physiology

Challenging the dogma : reevaluating the role of astrocyte calcium signaling in physiology

... Research on the function of resident microglial cells in their inactivated state has been difficult due to limitations of culturing cells or using acute brains slices. Methods used to study microglial cells typically ...

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Syncytium calcium signaling and macrophage function in the heart

Syncytium calcium signaling and macrophage function in the heart

... intracellular calcium signaling and intercellular electrical conduction via the syncytium network underlie the synchronized beating of the ...syncytium calcium signaling in the cardiomyocytes ...

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Role of Protons in Calcium Signaling

Role of Protons in Calcium Signaling

... calcium signaling have been identified [Pozzan 1994, Clapham 2007, Berridge 2012, Balla 2013, Carafoli 2016, Galione 2019], and the understanding of specific receptors [Rossi 2018, Prole 2019] and channels ...

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Altered calcium signaling in platelets from nitric oxide-deficient hypertensive rats

Altered calcium signaling in platelets from nitric oxide-deficient hypertensive rats

... intracellular calcium levels in many cell types of human and experi- mental hypertension ...cytosolic calcium levels which seems to be related, among others, with an enhanced vas- cular tone and with a ...

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Role of Protons in Calcium Signaling

Role of Protons in Calcium Signaling

... relation to calcium signaling. Given the chemical properties of these two ions and starting from the hypothesis that protons may have a stimulatory and not only regulatory role in the cell, it is possible ...

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Biological Function of Calcium-Sensing Receptor (CAS) and Its Coupling Calcium Signaling in Plants

Biological Function of Calcium-Sensing Receptor (CAS) and Its Coupling Calcium Signaling in Plants

... As mentioned location of CAS and calcium signaling sensor responder, it is hypothesized that CAS play a critical role during photosynthesis regulation process. Previous works confirmed the highlight induced ...

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Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways

Bifidobacterium dentium Fortifies the Intestinal Mucus Layer via Autophagy and Calcium Signaling Pathways

... FIG 8 B. dentium activates autophagy and stimulates calcium signaling. (A) qPCR analysis of autophagy genes in germfree mice (black dots, n ⫽ 20), live B. dentium-monoassociated mice (green dots, n ⫽ 20), ...

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Calcium signaling in neurodegeneration

Calcium signaling in neurodegeneration

... key signaling ion involved in many different intracellular and extracellular processes ranging from synaptic activity to cell-cell communication and ...brain, calcium is fundamental in the control of ...

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Calcium Signaling in Brain Cancers: Roles and Therapeutic Targeting

Calcium Signaling in Brain Cancers: Roles and Therapeutic Targeting

... Abstract: Calcium signaling, in addition to its numerous physiological roles, is also implicated in several pathological conditions including ...of calcium signaling in the promotion of ...

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Meeting Koch’s postulates for calcium signaling in cardiac hypertrophy

Meeting Koch’s postulates for calcium signaling in cardiac hypertrophy

... on calcium cycling, phospholam- ban, can completely prevent the onset of cardiac hypertrophy and block the induction of atrial natriuretic factor in a mouse model of dilated cardiomyopathy ...the calcium ...

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Axial tubule junctions control rapid calcium signaling in atria

Axial tubule junctions control rapid calcium signaling in atria

... The canonical atrial myocyte (AM) is characterized by sparse transverse tubule (TT) invaginations and slow intracellular Ca 2+ propagation but exhibits rapid contractile activation that is susceptible to loss of function ...

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Lipid rafts serve as signaling platforms for mGlu1 receptor-mediated calcium signaling in association with caveolin

Lipid rafts serve as signaling platforms for mGlu1 receptor-mediated calcium signaling in association with caveolin

... extracellular Ca 2+ [47]. It has been shown that enhanced mGluR signaling and Ca 2+ release regulated by IP3R were identified as underlying causes of the age-dependent cog- nitive phenotypes observed [48]. Also, ...

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Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus

Nucleoplasmic calcium signaling and cell proliferation: calcium signaling in the nucleus

... Although it is well known that nuclear Ca 2+ has bio- logical effects that differ from those mediated by increases in cytosolic Ca 2+ [21], the mechanisms by which Ca 2+ is specifically increased in the nucleoplasm are a ...

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The role of the actin cytoskeleton in calcium signaling in starfish oocytes

The role of the actin cytoskeleton in calcium signaling in starfish oocytes

... A clue was provided by the activation pathway of nitric oxide (NO), a signaling molecule acting through the elevation of cellular cGMP. The cGMP-dependence of the sea urchin ADP-ribosyl cyclase has prompted the ...

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Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling

Muscle lipogenesis balances insulin sensitivity and strength through calcium signaling

... mass spectrometry (Supplemental Table 1). It is likely that several of these proteins do not reside in the SR, given the sensitivity of mass spectrometry and possible contamination of the SR fraction with proteins from ...

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Kelch Repeat Protein Clakel2p and Calcium Signaling Control Appressorium Development in Colletotrichum lagenarium

Kelch Repeat Protein Clakel2p and Calcium Signaling Control Appressorium Development in Colletotrichum lagenarium

... Kelch repeat proteins are important mediators of fundamental cellular functions and are found in diverse organisms. However, the roles of these proteins in filamentous fungi have not been characterized. We isolated a ...

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Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone

Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone

... glutamate or GABA, receptors regulate the cell cycle We demonstrate, by directly imaging part of the mitotic process, that both muscarinic and purinergic stimulation may significantly af[r] ...

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