cAMP-dependent kinase activity
Adeno-Associated Virus Type 2 Rep78 Inhibition of PKA and PRKX: Fine Mapping and Analysis of Mechanism
... the kinase activity of PKA and PRKX toward the artificial heptapeptide substrate referred to as kemptide (LRRASLG) ...ATPase activity of Rep is constitu- tive and independent of a DNA substrate ...
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Counteracting Regulation of Chromatin Remodeling at a Fission Yeast cAMP Responsive Element-Related Recombination Hotspot by Stress-Activated Protein Kinase, cAMP-Dependent Kinase and Meiosis Regulators
... Figure 1.—The PKA pathway negatively regu- lates M26 chromatin re- modeling. (A) DNA se- quences of ade6 ⫹ , ade6- M375 (negative control), and ade6-M26 (recombina- tion hotspot) alleles. White letters indicate G to T ...
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PKA R1 spatially restricts Oskar expression for Drosophila embryonic patterning
... of cAMP-dependent protein kinase (Pka-R1) as a key factor in the restriction of Oskar protein to the posterior ...Serine/Threonine kinase that mediates various developmental processes by ...
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Intracellular signaling in the regulation of renal Na K ATPase I Role of cyclic AMP and phospholipase A2
... of cAMP-dependent protein kinase A (PKA), abolished the Na:K pump effect of all the cAMP agonists listed ...cell cAMP involves phospholipase A2 (PLA2), we used mepacrine, a PLA2 ...
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Regulation of the Subcellular Localization of Cyclic AMP-Dependent Protein Kinase in Response to Physiological Stresses and Sexual Differentiation in the Fission Yeast Schizosaccharomyces pombe
... protein kinase, also re- ferred to as protein kinase A (PKA), is a ubiquitous serine/ threonine kinase that functions in a variety of signal transduc- tion networks involved in the regulation of a ...
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Regulation of mRNA Export by Nutritional Status in Fission Yeast
... the cAMP-phosphodiesterase of ...of cAMP-dependent protein kinase activity by a Dbcy1 mutation (Tung and Hopper 1995), lacking the regula- tory subunit of cAMP protein ...of ...
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THE EFFECT OF THEOPHYLLINE ON THE KINETICS OF cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, cAMP, PROTEIN KINASE INHIBITOR AND THEIR RELATIONSHIP IN LUNG TISSUE
... of cAMP-dependent protein ...tllrough cAMP and recently many reports have indicated its involvement in ...the activity of cAMP-dependent protein kinase at the ceUular ...
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Hormonal modulation of cyclic adenosine 3',5' monophosphate dependent protein kinase activity in rat renal cortex Specificity of enzyme translocation
... by cAMP-dependent protein kinases, but little is known about hormonal control of endogenous protein kinase activity (PK) in ...on cAMP and PK in slices of rat renal ...enzyme ...
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In Vivo Activation of Protein Kinase A in Schizosaccharomyces pombe Requires Threonine Phosphorylation at Its Activation Loop and Is Dependent on PDK1
... Pka1 activity because functionally conserved between diverse ...are dependent on the nature The relationship between ksg1 and the cAMP-regu- of the pka1 ...
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IDENTIFICATION OF HUMAN cAMP DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT INHIBITORS
... holoenzyme activity is directly related to the progression of cancers 5 ...of cAMP dependent protein kinase catalytic subunit (PKACA) causes severe tumorgenesis in prostate and other cancers ...
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Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease
... Raf kinase inhibitor, attenuated cyst enlargement in vitro and in a nonorthologous rat model but failed to ameliorate renal enlargement or func- tion and promoted hepatic and renal fibrosis ...Raf kinase ...
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In vivo and in vitro models of demyelinating disease: activation of the adenylate cyclase system influences JHM virus expression in explanted rat oligodendrocytes.
... Chromatographic analysis of cAMP-dependent protein kinase activity in cytosol extracts prepared from astrocytes or oligodendrocytes revealed that both glial cell types were deficient in [r] ...
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Oligopeptide transporter PepT1 in Atlantic cod (Gadus morhua L ): cloning, tissue expression and comparative aspects
... conserved cAMP/cGMP-dependent protein kinase phosphorylation motif close to membrane-spanning domain IX (found in all vertebrate sequences with the exception of the human) and the adjacent protein ...
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Role of tyrosine phosphorylation in sperm capacitation / acrosome reaction
... The activity of PKA is depend- ent on the activities of adenylate cyclase and phosphodi- ...nine kinase, induces and causes an increase in tyrosine phosphorylation of sperm proteins, by indirect activation ...
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Mutation of the Regulator of G Protein Signaling Crg1 Increases Virulence in Cryptococcus neoformans
... the cAMP-dependent protein kinase A regulatory ...is dependent on the MAP kinase homolog Cpk1, cAMP signaling, and partially on the transcriptional factor homolog ...laccase ...
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Regulation of hormone sensitive calcium influx by the adenylyl cyclase system in renal epithelial cells
... reduced forskolin-sensitive cAMP production. alpha ilQ204L increased and alpha sQ227L decreased bradykinin-induced Ca influx across the cell membrane, but neither mutant affected bradykinin-stimulated ...
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sck1, a high copy number suppressor of defects in the cAMP-dependent protein kinase pathway in fission yeast, encodes a protein homologous to the Saccharomyces cerevisiae SCH9 kinase.
... sckl, a High Copy Number Suppressor of Defects in the CAMP-Dependent Protein Kinase Pathway in Fission Yeast, Encodes a Protein Homologous.. to the Saccharomyces cer[r] ...
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Relationship of the cAMP-dependent protein kinase pathway to the SNF1 protein kinase and invertase expression in Saccharomyces cerevisiae.
... Suppression of the R a f phenotype is not due to restoration of invertase expression: T h e snfl and snf4 mutants are defective i n growth on raffinose at least i n [r] ...
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Characterization of a protein cofactor that mediates protein kinase A regulation of the renal brush border membrane Na(+) H+ exchanger
... recognized by an affinity-purified polyclonal antibody to NHE-RF. Potential phosphorylation sites for protein kinase A are present. The mRNA for the protein is expressed in kidney, proximal small intestine, and ...
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Proteomic Analysis of Celecoxib on Chondrocytes from Patients with Osteoarthritis
... There are no evident treatments that cure OA or delay the disease progression as yet. Thus, the current goal of treatment is to modify symptoms of OA. Some guidelines recommend NSAIDs including selective COX-2 inhi- ...
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