Cancer biomarker
Epigenetic therapy of novel tumour suppressor ZAR1 and its cancer biomarker function
... WEE1 contains the motifs UUUGUCU at position 559, UUUAUCU at 988 and a duplicate of AUUGUCU at 1043 and 1156 of its 1164 bp 3’UTR. In WEE2 the motif UUUAUCU is found at 525 and 592 of its 951 bp 3’UTR. One duplicate ...
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A quantitative immunoassay for lung cancer biomarker CIZ1b in patient plasma
... 65-70kDa cancer-specific epitope does indeed contain CIZ1b sequences, we adopted an epitope reconstitution ...lung cancer patient ...CIZ1b biomarker recognised by 2B and ...65-70kDa ...
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ctDNA as a cancer biomarker: a broad overview
... The overall concordance between plasma and matched tumor tissues assessed by NGS is only approximately 25% (Pishvaian et al., 2017). Internal quality control guidelines and ctDNA reference materials are still not ...
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Identification of prostate cancer biomarkers in urinary exosomes
... for cancer biomarkers such as PSA (prostate cancer), CA-125 (ovarian cancer), and HER2/neu (breast ...the cancer biomarker field since this bio-fluid is obtained noninvasively and ...
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LKB1, A New Biomarker in Breast Cancer
... Despite the fact that ERα is a standard predictive marker used to prescribe endocrine therapy, about 40% of these patients initially display or eventually become resistant to treatment [7] [8]. This represents a burden ...
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ProNGF is a potential diagnostic biomarker for thyroid cancer
... thyroid cancer points to the potential clinical utility of a novel and reliable growth factor as a new diagnostic ...thyroid cancer continues to be a significant ...thyroid cancer biomarker ...
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Micro-RNA: biomarker for the treatment of cancer
... endometrial cancer, miR- 129-2 methylation is associated with microsatellite instability, MLH1 methylation and negative universal ...a cancer biomarker. Within cancer cells, miR-137 goals ...
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New generation of electrochemical immunoassay based on polymeric nanoparticles for early detection of breast cancer
... using CV. Consequently, we developed an extremely selective and sensitive bioassay with signal amplification capability. This new bioassay has numerous advantages over the existing techniques: 1) The amplification ...
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Validation and evaluation of a common biomarker in human cancers sera protein detected by a monoclonal antibody UNIVmAb
... 50 cancer patients samples (18 different cancer types of various grade) of different grades we predicted that the UNIVmAb might be used as a antibody to detect a common cancer ...common ...
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Deglycosylation and label-free quantitative LC-MALDI MS applied to efficient serum biomarker discovery of lung cancer
... lung cancer biomarker screening. Control and lung cancer sera were immuno- depleted, deglycosylated, purified on SDS-PAGE, in-gel digested and analyzed by LC-MALDI in the same way as described ...
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<p>Amyloid Beta (A4) Precursor Protein: A Potential Biomarker for Recurrent Nasopharyngeal Carcinoma</p>
... A preliminary analysis was performed to assess the poten- tial value of APP as a serum biomarker for rNPC. The serum samples of 70 patients with NPC (35 rNPC + 35 nrNPC) were initially collected because some ...
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Impact of aromatase inhibitor treatment on global gene expression and its association with antiproliferative response in ER+ breast cancer in postmenopausal patients.
... 1. Qiong Gao ELo-K, Maggie Chon U Cheang, James Morden, Ricardo Ribas, Kally Sidhu, David Evans, Vera Martins, Andrew Dodson,, Anthony Skene CH, Elizabeth Mallon, Abigail Evans, Judith M. Bliss, John Robertson, Ian ...
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<p>Progress in immunocytochemical staining for cervical cancer screening</p>
... cervical cancer screening, the integration of more sensitive and specific biomarkers can improve the accuracy of cervical cancer screening and reduce unneces- sary invasive ...attractive biomarker ...
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Biomarkers for early diagnosis, prognosis, prediction, and recurrence monitoring of non-small cell lung cancer
... A large variety of substrates in the circulation can be obtained from liquid biopsy samples and used for biomarker analysis, such as circulating tumor cells (CTCs), ctDNA, microRNA (miRNA), and serum proteins. ...
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Imaging biomarker roadmap for cancer studies.
... because biomarker drift is inevitable owing to technological advances in scanner performance (for example, clinical trials with ongoing data collection can be affected by hardware and soft- ware ...
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Circulating DNA as biomarker in breast cancer
... with cancer, screening of plasma or serum DNA may provide information on genetic and epigenetic profiles associated with breast cancer development, progression, and response to ...
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MRE11 as a Predictive Biomarker of Outcome After Radiation Therapy in Bladder Cancer.
... We failed to validate the previous findings from us and others (6, 7). Although this could be due to lack of biological effect, we think it more likely to be due to methodological issues, including problems in ...
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Original Article UCH-LI acts as a novel prognostic biomarker in gastric cardiac adenocarcinoma
... In this study we screened the expression profile of UCH-L1 in 196 cases GCA by tissue microar- ray and immunohistochemistry and identified this protein as a predictive biomarker of out- come of GCA patients. To ...
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Network vulnerability-based and knowledge-guided identification of microRNA biomarkers indicating platinum resistance in high-grade serous ovarian cancer
... As reported by Lin et al. [16], miRNAs with significantly high number of single-line regulation in the miRNA- mRNA network (NSR) values possess stronger inde- pendent regulatory ability, which are vulnerable and ...
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Noninvasive multianalyte diagnostic assay for monitoring bladder cancer recurrence
... bladder cancer recurrence were analyzed for matrix metalloproteinase-2 levels, the presence of mutant FGFR3 DNA, and hypermethylation of the NID2 and VIM ...bladder cancer was determined by FGFR3 alone or ...
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