Cancer Metastasis
Mouse models of breast cancer metastasis
... breast cancer is relatively simple and allows the genetic or pharmacological manipulation of the implanted ...breast cancer patient support the growth of a breast carcinoma cell line better than the normal ...
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<p>The role of Clusterin in cancer metastasis</p>
... promotes cancer invasion and ...diagnose cancer early ...delays cancer metastasis and enhances the sensitivity of cytotoxic ...of metastasis and to enhance the tumoral sensitivity to ...
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AN INSIGHT INTO BREAST CANCER METASTASIS TO BONE
... Breast cancer is the second leading fatal cancer in women following lung ...for metastasis, proliferation and colonization of cancerous cells to the ...of metastasis is a multistep ...breast ...
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Role of the nervous system in cancer metastasis
... of cancer- related ...fluence metastasis have been identified, there are still needs to conduct comprehensive evaluation of the fac- tors that contribute to cancer ...influences cancer ...
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Cancer metastasis: enactment of the script for human reproductive drama
... of cancer metastasis to human reproduction becomes evident despite some osten- sible ...the cancer reproductive saga starts with the separation of metastasis initiating cells (MICs) from ...
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Targeting invadopodia to block breast cancer metastasis
... of cancer cell ...breast cancer metastasis will involve not only designing trials to maximize the impact of the therapeutics, but also finding novel inhibitors with greater specificity and fewer ...
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Review Article Metastasis associated in colon cancer 1 (MACC1): at the crossroads of cancer metastasis and drug resistanced
... Cancer metastasis and drug resistance results from several selective forces, and are closely correlated with the clinical outcomes of cancer patients ...therapy. Metastasis associated in colon ...
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Regulation of cancer metastasis by microRNAs
... of metastasis-relevant miRNAs has been recently unrav- ...breast cancer metastasis suppressor 1(BRMS1) plays an important role in the transcription of several metastasis-relevant ...for ...
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Molecular biology of breast cancer metastasis Genetic regulation of human breast carcinoma metastasis
... cloned metastasis-suppressor gene, Nm23, was identified in the murine K1735 melanoma using subtrac- tive hybridization, because its expression was inversely correlated with lung ...fide metastasis- ...
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Role of platelets and platelet receptors in cancer metastasis
... The role of platelets in angiogenesis has long been rec- ognized in several in vitro and in vivo studies applying diverse angiogenic assays [117]. Several molecules, stored in platelets’ α-granules exhibit proangiogenic ...
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Role of miR 10b in breast cancer metastasis
... esophageal cancer cell migration and invasion – has been identifi ed as a direct target of miR-10b in esophageal squamous cell carcinoma cells (Figure 1) ...
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The immune system in cancer metastasis: friend or foe?
... simulates metastasis. Models of spontaneous metastasis, such as the classic 4 T1 breast cancer, or more recent genetically engineered mouse models typically take some time to develop true metasta- ...
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Factors contributing to the occurrence of cancer metastasis to brain
... a cancer patient when there is metastasis to brain the prognosis becomes very ...get metastasis to brain. In this study, in patients with brain metastasis, the demographic profile, the site of ...
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Pathobiology of cancer metastasis: a short account
... Primary cancer cells and their associated reactive stro- mal cells secrete humoral factors including an array of cytokines, chemokines and growth factors which deter- mine tropism for specific distant tissues, and ...
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Notch and Breast Cancer Metastasis
... importantly, cancer-induced sprouting neovasculature can promote tip cells to secret POSTN (POSTN associates with Notch1 physically at its EGF repeats [85, 86]) to bind to TNC and ECM and help TNC deposition on ...
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Dihydroartemisinin inhibits TCTP-dependent metastasis in gallbladder cancer
... for metastasis [30–32], and activated Cdc42 phosphorylates the p21-activated kinases PAK1 and PAK2, which in turn initiate actin reorganization and regulate cell adhesion, migration, and invasion ...
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Gene signatures of breast cancer progression and metastasis
... the metastasis suppressor genes BRMS1, KISS1 (kisspeptin), KAI1 (CD82) and Mkk4 (MAP2K4; mitogen-activated protein kinase kinase 4) have been shown in breast cancer brain metastasis [8], with specifi ...
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<p>Metastasis inhibition in breast cancer by targeting cancer cell extravasation</p>
... breast cancer metastasis is found in the lungs, liver, bones and brain resulting in unfavorable ...breast cancer patients, observed that the organ distribution of metastases hap- pened in a nonrandom ...
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ACLY facilitates colon cancer cell metastasis by CTNNB1
... Previously, researchers mainly focus on glucose and glutamine metabolism in the field of tumor metabolism and metastasis. There are few studies on lipid metabol- ism in tumor metastasis. Altered lipid ...
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Issues on peritoneal metastasis of gastric cancer: an update
... Generally speaking, it is accepted that PM is achieved by the implantation of peritoneal free tumor cells. Hence, to eliminate the peritoneal free tumor cells before the actual achievement of PM, taking some effective ...
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