canonical Wnt pathway
Formation of the head organizer in hydra involves the canonical Wnt pathway
... the canonical Wnt pathway have been identified in hydra, and their expression patterns suggest that this pathway plays a role in this structure (Hobmayer et ...
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A review of the evidence for the canonical Wnt pathway in autism spectrum disorders
... the canonical Wnt pathway can contribute to individual forms of autism spectrum ...in Wnt signaling (SNPs in MARK1 and EN2 that increase gene transcription, PTPRZ1 deletion, cadherin ...
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Notch signaling augments the canonical Wnt pathway to specify the size of the otic placode
... the canonical Wnt pathway to specify the size of the otic placode Chathurani ...that Wnt signaling mediates this placode-epidermis fate ...the Wnt and Notch signaling pathways during ...
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Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation
... the canonical WNT pathway. In addition, ERK1/2 pathway activity is also decreased by sFRP1 treat- ment in the majority of the cancer cells, with SkBr3 cells being particularly ...that ...
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Filamin A and formin 2 dependent endocytosis regulates proliferation via the canonical Wnt pathway
... the actin cytoskeleton direct PCP to maintain the neuroepithelium. Our current studies now provide a parallel mechanism for actin cytoskeletal regulation through the canonical Wnt pathway. Binding of ...
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SFRP2 enhances the osteogenic differentiation of apical papilla stem cells by antagonizing the canonical WNT pathway
... Besides, this has shown that SFRP2 had no effect on wnt5a expression at the mRNA level. It is speculated that SFRP2 might not affect the non-canonical wnt pathway. For other cell types and disease ...
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Flamingo, a cadherin type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis
... with wnt signaling in the anterior – posterior patterning of the neural plate, a process which, like dorsal – ventral patterning, is dependent on the canonical wnt ...of wnt signaling is ...
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Mutual Reinforcement Between Telomere Capping and Canonical Wnt Pathway Activity in the Intestinal Stem Cell Niche
... with Wnt pathway agonists, as well as enhanced survival and Lgr5 expression in cultured mTR-/- intestinal ...by Wnt pathway activation, were observed in human cells suffering from telomere ...
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Blockade of CXCL12/CXCR4 signaling inhibits intrahepatic cholangiocarcinoma progression and metastasis via inactivation of canonical Wnt pathway
... the Wnt/β-catenin signaling pathway, and activa- tion of CXCR4 expression led to the constitutive activation of β-catenin, implying the important role of Wnt/β-catenin in CXCR4 signaling, which was ...
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Gene expression analysis of canonical Wnt pathway transcriptional regulators during early morphogenesis of the facial region in the mouse embryo
... compilation. Wnt signalling is essential for regional specification of the face and the differential distribution of pathway components must drive the precise localisation of Wnt signalling ...of ...
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Targeting the canonical Wnt/β-catenin pathway in hematological malignancies
... the canonical Wnt pathway in hematological malig- ...of Wnt antagonists including SFRPs, DKKs, and WIF-1 is detected in several types of hematological malignancies, (44–48) and is associated ...
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The Canonical Wnt/β-catenin Pathway as a Therapeutic Target in Multiple Myeloma
... The canonical Wnt signalling pathway modulates the balance between stemness and differentiation in several adult stem cell niches, including haemopoiesis within the bone marrow 4 ...of ...
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Thermodynamics in cancers: opposing interactions between PPAR gamma and the canonical WNT/beta-catenin pathway
... The WNT/beta‑catenin pathway induces the transcription of genes involved in cell proliferation, ...PI3K‑AKT pathway induces an increase of the aerobic ...the canonical WNT ...
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Moringin activates Wnt canonical pathway by inhibiting GSK3β in a mouse model of experimental autoimmune encephalomyelitis
... Keywords: Wnt–β-catenin pathway, GSK3β, multiple sclerosis, moringin, PPARγ, apoptosis Introduction The central logic of the Wnt– β -catenin-dependent or Wnt canonical pathway ...
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The role of canonical and non-canonical WNT signalling pathways in load induced cartilage degradation.
... of WNT signalling in cartilage homeostasis WNT signalling also has an integral role in maintaining postnatal cartilage homeostasis as demonstrated by in vivo ...the canonical and non- ...
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Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/β-catenin Pathway in Gastric Cancer
... FZD7-dependent canonical Wnt signaling promotes breast cancer stem cell activity ...activates canonical Wnt/β-catenin pathway and promotes EMT in non-transformed hepatic cells ...
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Role of Wnt pathway on rheumatoid arthritis
... the Wnt/β- catenin signaling (canonical Wnt pathway; .... Canonical Wnt pathway determines the fate of mesenchymal stem cells 38 ...of WNT proteins, GSK-3β ...
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Canonical Wnt signaling: high throughput RNAi widens the path
... the pathway. This is because virtually all the key elements of the canonical Wnt pathway known so far are well conserved between flies and ...on Wnt signaling in a variety of systems, ...
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Canonical WNT signaling components in vascular development and barrier formation
... encoding canonical WNT pathway members to evaluate the exact contribution of these components in CNS vascular development and in specification of the blood-brain barrier (BBB) and blood-retina ...
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Canonical Wnt signaling through Lef1 is required for hypothalamic neurogenesis
... the canonical pathway during hypothalamic ...the canonical Wnt pathway in this ...for Wnt/ -catenin signaling in hypothalamic ...
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