Capsular polysaccharides
Serological and Genetic Diversity of Capsular Polysaccharides in Enterococcus faecalis
... possess capsular carbohydrate antigens that are targets of opsonic ...of capsular polysaccharides in Enterococcus ...biosynthetic capsular polysaccharide (cps) ...
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Identification of the Capsular Polysaccharides in Staphylococcus aureus Clinical Isolates by PCR and Agglutination Tests
... two capsular polysaccharides, types 5 and 8, on the surface of clinical isolates led to the development of a conjugate vaccine (StaphVAX) based on capsular polysaccharides types 5 and 8 ...
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Effects of Ageing and Gender on Naturally Acquired Antibodies to Pneumococcal Capsular Polysaccharides and Virulence-Associated Proteins
... Elderly individuals are susceptible to pneumococcal infections. Although factors contributing to the increased suscep- tibility of the elderly to bacterial infections may be several, compromised immune function, a ...
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Naturally Acquired Antibodies against Four Enterococcus faecalis Capsular Polysaccharides in Healthy Human Sera
... Human sera contain IgG and IgM antibodies directed against capsular polysaccharides of four E. faecalis prototype strains. Using the CPS-ELISA, IgG and IgM antibodies against the CPS of all four E. faecalis ...
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Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein
... conjugation) capsular polysaccharides from ...pneumoniae polysaccharides 24 ; (ii) the tetanus toxoid protein 25 and (iii) on the Hib-TT system ...
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Direct testing of blood culture for detection of the serotype 5 and 8 capsular polysaccharides of Staphylococcus aureus
... Direct Testing of Blood Cultures for Detection of the Serotype and 8 Capsular Polysaccharides of Staphylococcus aureus.. Monoclonal antibodies MAbs reactive with serotype 5 and 8 capsula[r] ...
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Molecular epidemiology and expression of capsular polysaccharides in Staphylococcus aureus clinical isolates in the United States
... Staphylococcus aureus capsular polysaccharides (CP) are important virulence factors under evaluation as vaccine antigens. Clinical S. aureus isolates have the biosynthetic capability to express either CP5 ...
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Specificities and Opsonophagocytic Activities of Antibodies to Pneumococcal Capsular Polysaccharides in Sera of Unimmunized Young Children
... An enzyme immunoassay (EIA) for antibodies to pneumococcal capsular polysaccharides (Pnc PSs) detects in some cases antibodies that are cross-reactive within different Pnc PSs. Recently, it has been ...
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Therapeutic properties in Tunisian hot springs: first evidence of phenolic compounds in the cyanobacterium Leptolyngbya sp biomass, capsular polysaccharides and releasing polysaccharides
... In this study, we have also demonstrated that the high- est content of MAAs was observed for CME which means that Leptolyngbya sp. has the ability to accumu- late MAAs in its capsular polysaccharides. The ...
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Novel Multiplex Immunoassays for Quantification of IgG against Group B Streptococcus Capsular Polysaccharides in Human Sera
... tract in 11 to 35% of pregnant women and can be transmitted to the neonate during pregnancy, labor, and delivery (3). Intrapartum antibiotic prophylaxis can protect the baby from infection in the first week of life ...
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Production of polyclonal and monoclonal antibodies against group A, B, and C capsular polysaccharides of Neisseria meningitidis and preparation of latex reagents
... Polyclonal and monoclonal antibodies against capsular polysaccharides of Neisseria meningitidis serogroups A, B, and C were produced in order to develop immunological reagents allowing b[r] ...
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Are the Enzyme Immunoassays for Antibodies to Pneumococcal Capsular Polysaccharides Serotype Specific?
... pneumococcal capsular polysaccharides (Pnc PSs) measured by enzyme immunoassay (EIA) was studied by inhibition of antibody binding by homologous and heterologous ...
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Measurement of antibodies against meningococcal capsular polysaccharides B and C in enzyme-linked immunosorbent assays: towards an improved surveillance of meningococcal disease.
... the capsular polysaccharides are not detected in the MAT; a serological test capable of identifying serogroup B- and C- specific antibodies would improve epidemiological surveil- ...
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Simplified procedure for preparation of sensitized latex particles to detect capsular polysaccharides: application to typing and diagnosis of Actinobacillus pleuropneumoniae
... specific antibodies on the latex particles that cross-react with other bacterial or host components are present (7, 8). Poor specificity may be a particular problem when testing for poorly immunogenic capsular ...
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Assignment of Immunoglobulin G1 and G2 Concentrations to Pneumococcal Capsular Polysaccharides 3, 6B, 14, 19F, and 23F in Pneumococcal Reference Serum 89-SF
... Immunoglobulin G (IgG) subclass determinations are im- portant for many reasons. Vaccination with plain PS such as pneumococcal PS (Pnc PS) elicits antibodies that are restricted to the rare IgG2 subclass in humans (3, ...
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Comparative Evaluation of Profiles of Antibodies to Mycobacterial Capsular Polysaccharides in Tuberculosis Patients and Controls Stratified by HIV Status
... the polysaccharides glucan (70 to 80%) and arabinomannan (AM) (10 to 20%) and, to a lesser extent, of pro- teins and glycolipids (8, 23, ...cells, capsular antigens are involved in mycobacterial ...
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Evaluation of a Validated Luminex-Based Multiplex Immunoassay for Measuring Immunoglobulin G Antibodies in Serum to Pneumococcal Capsular Polysaccharides
... The third objective of this study was to compare the proportion of vaccine responders indicated by ELISA to the theoretical response rate indicated by the dLIA platform using either the [r] ...
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Development and Validation of 13-plex Luminex-Based Assay for Measuring Human Serum Antibodies to Streptococcus pneumoniae Capsular Polysaccharides
... microspheres. Capsular PnPS serotypes 1, 3, 4, 5, 6A, 6B, 9V, 14, 18C, 19A, 19F, and 23F (Pfizer Vaccine Research and Development, Pearl River, NY) are aminated by conjugation to poly- L -lysine (hydrobromide) ...
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Thermodynamics and Density of Binding of a Panel of Antibodies to High-Molecular-Weight Capsular Polysaccharides
... Published estimates of the lengths of extended PS chains range from approximately 0.43 nm to 0.56 nm per monosac- charide residue (1, 19, 25). Therefore, the spacing of the bind- ing of the Fabs along the PS calculated ...
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Method for Simultaneous Measurement of Antibodies to 23 Pneumococcal Capsular Polysaccharides
... spheres were washed by adding 500 l of 100 mM 2-(N-morpholino)-ethanesul- fonic acid (MES) (pH 6.0) (Sigma), microcentrifuging at 10,000 ⫻ g for 1 min at room temperature, and aspirating the supernatant. The microsphere ...
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