Carbonic Anhydrase
Increased expression of carbonic anhydrase I in the synovium of patients with ankylosing spondylitis
... In the current study, comparative 2-DE was used to dif- ferentiate protein expression levels between the synovial membranes from AS and RA patients and AS and OA patients on a global scale. The experimental 2-DE gel ...
11
SCREENING OF UNIQUE BINDING SITE SPECIFIC LIGAND FOR CARBONIC ANHYDRASE IX
... ABSTRACT: Cancer is a common and widespread cause of human death in the world. Treatments like chemotherapy and radiotherapy facilitate in prolonging the patient’s life however in some cases cancer can be prevented. ...
7
Active site and kinetic studies on carbonic anhydrase III
... Carbonic anhydrase III is by far the major soluble CA in red mammalian skeletal muscle and primarily accounts for any CA activity in the cytoplasmic fraction of this tissue (Fremont et ...
276
Internephron heterogeneity for carbonic anhydrase independent bicarbonate reabsorption in the rat
... The most likely explanation for the observed findings is that amiloride, by inhibiting distal carbonic anhydrase-independent bicarbonate reabsorption, uncovers a greater distal delivery [r] ...
13
A distinct carbonic anhydrase in the mucus of the colon of humans and other mammals
... We have collected gastrointestinal, mainly colonic, mucus from humans, guinea pigs, rats, and normal and carbonic anhydrase II (CAII)-deficient mice. In the mucus of all species, substantial CA activity was ...
10
Environmentally mediated carbonic anhydrase induction in the gills of euryhaline crustaceans
... Branchial carbonic anhydrase activity in anterior (G3; hatched columns) and posterior (G7; open columns) gills of blue crabs acclimated for 3 weeks to various ...
12
Effect of Carbonic Anhydrase Inhibitor Combination on Fertility Male Rats
... the carbonic anhydrase activity of the testes and carbonic anhydrase inhibitor drugs which is agreement with [15, ...demonstrated carbonic anhydrase inhibitor significantly ...
6
Carbonic Anhydrase III S Glutathionylation Is Necessary for Anti Oxidant Activity
... Intracellular pH is partly regulated by a family of carbonic anhydrase (CA, EC4.2.1.1) enzymes that reversibly catalyse the hydration of carbon dioxide to bicarbonate and hydrogen ions [1]. The α -CAs ...
11
Carbonic Anhydrase QSAR Model as Templates for Biomarkers Discovery
... [6]. Ugochukwu, E., Shafqat, N., Pilka, E., Chaikuad, A., Krojer, T., Muniz, J., Kim, J., Bray, J., Bountra, C., Arrowsmith, C.H., Weigelt, J., Edwards, A., von Delft, F., Carpenter, E.P., Yue, W.W., Oppermann,, Crystal ...
5
Renal bicarbonate reabsorption in the rat I Effects of hypokalemia and carbonic anhydrase
... Free-flow micropuncture studies were carried out on superficial rat proximal and distal tubules to assess the participation of different nephron segments in bicarbonate transport. Particular emphasis was placed on the ...
11
Direct evidence of participation of rat lung carbonic anhydrase in CO2 reactions
... of carbonic anhydrase activity, the catalysis must have occurred during transit through the isolated ...the carbonic anhydrase of isolated lungs accelerates the conversion of H2CO3 to CO2 and ...
6
P-glycoprotein-mediated chemoresistance is reversed by carbonic anhydrase XII inhibitors
... Carbonic anhydrase XII (CAXII) is a membrane enzyme that maintains pH homeostasis and sustains optimum P-glycoprotein (Pgp) efflux activity in cancer ...of carbonic anhydrase IX had no effect ...
15
Expression and localization of carbonic anhydrase and ATPases in the symbiotic tubeworm Riftia pachyptila
... The trophosome consists of numerous lobules, each of these being a functional unit (Fig. 4A). Each lobule is provided with an axial efferent blood vessel, several afferent vessels situated at the periphery of the lobule, ...
11
Carbonic anhydrase in the midgut of larval Aedes aegypti: cloning, localization and inhibition
... a carbonic anhydrase cDNA was cloned from larval ...mosquito carbonic anhydrase and, indeed, it is the first to be cloned from any ...mosquito carbonic anhydrase revealed that ...
12
Amino Acids as Building Blocks for Carbonic Anhydrase Inhibitors
... containing amino acid moiety act as effective and selective inhibitors of tumor-associated carbonic anhydrase 638. XII[r] ...
22
AN ANALYSIS OF BICARBONATE REABSORPTION DURING PARTIAL INHIBITION OF CARBONIC ANHYDRASE
... The two larger doses of acetazolamide reduced reabsorptive rates significantly even at the lowest plasma levels studied, thus suggesting that carbonic anhydrase activity is involved in t[r] ...
9
Properties of a carbonic anhydrase inhibitor protein in flounder serum
... the carbonic anhydrase inhibitor ...The carbonic anhydrase activity of flounder haemolysate was inhibited exclusively by the fractions belonging to a small peak in the chromatogram, which ...
7
The distribution of branchial carbonic anhydrase and the effects of gill and erythrocyte carbonic anhydrase inhibition in the channel catfish Ictalurus punctatus
... THE DISTRIBUTION OF BRANCHIAL CARBONIC ANHYDRASE AND THE EFFECTS OF GILL AND ERYTHROCYTE CARBONIC ANHYDRASE INHIBITION IN THE CHANNEL CATFISH ICTALURUS PUNCTATUS BY RAYMOND P.. HENRY Dep[r] ...
18
Characterisation of carbonic anhydrase in the symbiotic dinoflagellate Symbiodinium
... Carbon dioxide and light regulation of promoters controlling the expression of mitochondrial carbonic anhydrase in Chlamydomonas reinhardtii.. Evolutionary analysis of orthologous cDNA s[r] ...
255
Deficiency of carbonic anhydrase in the vasculature of rabbit kidneys
... insufficient carbonic anhydrase ...of carbonic anhydrase, the renal venous outflow patterns of 14CO2 and H14CO3- became the same in the perfused ...
14