* Carcinoma/metabolism
TET2 suppresses nasopharyngeal carcinoma progression by inhibiting glycolysis metabolism
... NPC metabolism [15]. Glycolytic metabolism is essential for the perpetual proliferation of tumor cells, and is tightly controlled by various glyco- lytic enzymes, of which hexokinase (HK), phosphofruc- ...
14
LncRNA ANRIL is up-regulated in nasopharyngeal carcinoma and promotes the cancer progression via increasing proliferation, reprograming cell glucose metabolism and inducing side- population stem-like cancer cells
... glucose metabolism via increasing glucose uptake for glycolysis, which was regulated by the mTOR signal pathway to affect the expression of essential genes in ...glucose metabolism and inducing ...
14
Ovarian clear cell carcinoma meets metabolism; HNF-1β confers survival benefits through the Warburg effect and ROS reduction
... cell carcinoma (OCCC) constitutes one of the subtypes of ovarian cancers, but it has unique clinical, histological and biological characteristics, one of which is ...cancer-specific metabolism and how they ...
11
Expression of Sarcosine Metabolism Related Proteins in Invasive Lobular Carcinoma: Comparison to Invasive Ductal Carcinoma
... lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) and to determine the implications of these ...sarcosine metabolism-related proteins [glycine N-methyltransfer- ase, sarcosine ...
10
Gene network analysis reveals a novel 22-gene signature of carbon metabolism in hepatocellular carcinoma
... carbon metabolism genes may influence HCC patients survival [21, ...Hepatocellular Carcinoma (TCGA, Provisional) data set, which includes both mRNA expression and survival information of 373 HCC patients as ...
14
Metabolism-related enzyme alterations identified by proteomic analysis in human renal cell carcinoma
... cell carcinoma (RCC) is one of the most common types of kidney neoplasia in Western countries; it is relatively resistant to conventional chemotherapy and ...impaired metabolism leading to the initiation of ...
11
Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism
... The metabolism of tumor cells differs from that of normal ...energy metabolism is a new feature of malignant ...energy metabolism in the process of tumorigenesis and ...
13
Cancer Metabolism as a Mechanism of Treatment Resistance and Potential Therapeutic Target in Hepatocellular Carcinoma
... 53. Rahman MA, Kyriazanos ID, Ono T, Yamanoi A, Kohno H, Tsuchiya M, et al. Impact of PTEN expression on the outcome of hepatitis C virus-positive cirrhotic hepatocellular carcinoma pa- tients: possible ...
7
The effect of FASN inhibition on the growth and metabolism of a cisplatin-resistant ovarian carcinoma model.
... In this study, we have explored the use of the FASN inhibitor orlistat as a way of overcoming resistance to cisplatin in cisplatin-refractory ovarian cancer and examined their effects as monotherapies or as a ...
28
Metabolism of testoterone and related steroids in metastatic interstitial cell carcinoma of the testis
... If a significant fraction of the urinary testosterone glucuronide had been derived from a testosterone compartment other than the plasma testosterone compartment, the production rate est[r] ...
11
THE EFFECT OF DIETHYLSTILBESTROL ON THE CALCIUM, PHOSPHORUS AND NITROGEN METABOLISM OF PROSTATIC CARCINOMA
... A positive calcium balance on a low calcium diet was achieved by estrogen therapy, due to the decline in urinary calcium excretion initially and a decline in fecal calcium excretion in t[r] ...
8
THERAPEUTIC EFFECT OF TRIDHAM AND 1,2,3,4,6 PENTA O GALLOYL Î’ D GLUCOSE ON ALTERED ENERGY METABOLISM IN MAMMARY CARCINOMA BEARING RATS
... Phosphoglucoisomerase serves as a good index of tumor growth and is significantly elevated in cancerous animals. In agreement with our study, Campbell and King [41] have reported that phosphoglucoisomerase is an ...
6
Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma
... altered metabolism through altered transcriptional ...intrinsic metabolism of ccRCC TIL from 54 ...cell metabolism may improve functionality of T cells in the ccRCC tumor ...
14
Emerging roles of long non-coding RNAs in tumor metabolism
... cell carcinoma cells by downregulating Bcl2 expression and thereby stimulat- ing the mitochondrial pathway [101]; similarly, block- age of oncogenic HOTAIR induces mitochondrial calcium uptake 1 (MICU1)-dependent ...
16
Addressing metabolic heterogeneity in clear cell renal cell carcinoma with quantitative Dixon MRI
... shown increased accumulation of cholesterol in ccRCC (11, 12). Altogether, these observations strongly suggest that reprogrammed lipid metabolism in ccRCC may provide not only biomarkers of oncological aggression, ...
15
Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models
... Colon carcinoma cells cultured under starvation conditions exhibit a significant reduction of glucose avidity and consumption. GLUT1, a member of the GLUT (SLC2A) family of membrane transporters that mediates ...
14
The metabonomics study of P-selectin glycoprotein ligand-1 (PSGL-1) deficiency inhibiting the progression of atherosclerosis in LDLR-/- mice
... With the development of atherosclerosis, PSGL-1 deficiency induced the changes of amino acid metabolism, including the increased glycine, valine, glutamine and alanine. Glycine is useful for the effects of ...
11
Dynamic Changes in Serum Metabolomic Profiles of Growing Pigs Induced by Intravenous Infusion of Sodium Butyrate
... the metabolism of sugars, lipids, and amino acids ...the metabolism of TCA ...acid metabolism and amino acid metabolism, which was firmly confirmed in this ...energy metabolism through ...
15
Biosorption of Heavy Metals by Pseudomonas Bacteria
... Transport of the metal across the cell membrane yields intracellular accumulation, which is dependent on the cell's metabolism. This means that this kind of biosorption may take place only with viable cells. It is ...
5
Infiltrating lobular carcinoma of the breast: tumor characteristics and clinical outcome
... ductal carcinoma (IDC), knowledge about the clinical outcome of lobular carcinoma has been based on studies including relatively small numbers of ...
8