Cardiac metabolism
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
... tic cardiac growth (21, ...regulating cardiac metabolism and mitochondrial bio- ...glucose metabolism we saw, as HIF-1α levels did not change with Myc activation (data not shown), and LDHA ...
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PGC-1: The Energetic Regulator in Cardiac Metabolism
... of cardiac diseases via regulation of their coactivated targets, ...of cardiac diseases, accompanied by energetic abnormalities in the ...of cardiac metabolism regarding PGC-1 in ...
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PPARs modulate cardiac metabolism and mitochondrial function in diabetes
... Cardiac metabolism in normal and diabetic hearts Fatty acids and glucose are principle substrates for myo- cardial energy ...The cardiac oxygen consumption for adenosine triphosphate (ATP) production ...
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Computational studies of the effects of myocardial blood flow reductions on cardiac metabolism
... modeling cardiac metabolism, only key physiological aspects were included to reduce complexity and allow comparison with available in vivo ...cardial metabolism during ...
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Impairment of cardiac metabolism and sympathetic innervation after aneurysmal subarachnoid hemorrhage: a nuclear medicine imaging study
... of cardiac metabolism has been revealed in various situations of sympathetic stimulation such as chronic heart failure [21] and Takotsubo cardiomyopathy (TTC) ...glucose metabolism is impaired. ...
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Changes to both cardiac metabolism and performance accompany acute reductions in functional capillary supply
... to cardiac mechanical performance than coronary artery ligation: occluding 10% of arterioles with microspheres led to a 50% reduction in RPP implying a high degree of sensitivity for mechanical work to changes in ...
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Cardiac metabolism in a new rat model of type 2 diabetes using high-fat diet with low dose streptozotocin
... in cardiac substrate metabolism [3-6], with glucose metabolism suppressed and fatty acids metabolism elevated, charac- teristic of the Randle cycle ...fat metabolism, and is in- creased ...
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The Effect of Prolonged Administration of Ethanol on Cardiac Metabolism and Performance in the Dog
... HR, heart rate; MAP, mean aortic pressure; LVP, left ventricular pressure; LVEDP, left ventricular end-diastolic pressure; TCF, total coronary flow; CO, cardiac output; Vo2, oxygen consu[r] ...
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Cardiac mitochondrial metabolism may contribute to differences in thermal tolerance of red and white blooded Antarctic notothenioid fishes
... their cardiac metabolism have been described (Beers and Sidell, 2011; Devor et ...measured cardiac mitochondrial function, adenylate and lactate levels, and maximal activities of CS and lactate ...
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Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation
... adverse cardiac remodeling, we initially pursued a proteomics approach in which normal mouse hearts were compared with hearts from mice with cardiomyocyte-targeted Nox4 overexpression or cardio- myocyte-targeted ...
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Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice
... a cardiac-specific deletion of Hdac3 survived until 3–4 months of ...massive cardiac hypertrophy and upregulation of genes associated with fatty acid uptake, fatty acid oxidation, and electron ...
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Effect of Diabetes on Nitric Oxide Metabolism During Cardiac Surgery
... and metabolism of GTN. The mechanism by which GTN affects NO metabolism remains undefined (42,43), but it is possible to speculate that GTN acts directly or indirectly on the enzyme guan- ylate cyclase by a ...
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Association of plasma osteoprotegerin and adiponectin with arterial function, cardiac function and metabolism in asymptomatic type 2 diabetic men
... glucose metabolism has been documented before by others ...glucose metabolism, but not with cardiac ...of cardiac structure and function in healthy adults [34], elderly [35] and patients with ...
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Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism
... endogenous NO in cardiac muscle from diabetic dogs. However, in this recent study based on our gene expres- sion profiling of cardiac tissues from DM dogs, there is strong evidence of a dysfunction of the ...
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GRMD cardiac and skeletal muscle metabolism gene profiles are distinct
... to normal for LV and MG tissues and used those separ- ately generated lists to find GRMD driven differences between the two tissue types. To identify GRMD skel- etal- and cardiac muscle- specific gene expression ...
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Induced Tachycardia: Its Effect upon the Coronary Hemodynamics, Myocardial Metabolism and Cardiac Efficiency of the Intact Dog
... As the arterial/ coronary sinus oxygen differences did not vary greatly, the changes in the cardiac metabolic rates for oxygen and carbon dioxide were a function of the increased coronar[r] ...
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CORRELATIVE OBSERVATIONS ON CEREBRAL METABOLISM AND CARDIAC OUTPUT IN MYXEDEMA
... The data are compatible with the interpretation that the mental changes in myxedema are the result of decreased cerebral oxygen and glucose metabolism and that the reduction in cardiac o[r] ...
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The effects of intra aortic counterpulsation on cardiac performance and metabolism in shock associated with acute myocardial infarction
... perfusion, and probably improves myocardial contractility in the severely diseased heart. Before treatment, decreases in cardiac index (mean value, 1.22 liter/min per m 2 ), systolic ejection rate (67 ml/sec), and ...
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17ß Estradiol protects against the effects of a high fat diet on cardiac glucose, lipid and nitric oxide metabolism in rats
... One of the leading causes of morbidity and mortality in the developed world is obesity-associated cardiovascular disease (Lavie et al. 2014). Substantial evidence implies a direct causation between obesity and the ...
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Cardiac Angiosarcoma of the Right Atrium with Cardiac Tamponade
... Presentation of Case: A 56-year-old man presented with loss of consciousness. An echocardiogram showed cardiac tamponade, requiring an emergent exploration of the pericardium. We confirmed that the tumor ...
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