Cardiac Myocytes
The lethal effects of cytokine induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta
... in cardiac contractility, but the cytotoxic potential of nitric oxide with respect to the heart has not been ...on cardiac myocyte cytotoxicity, we exposed adult rat cardiac myocytes to either ...
10
Using Delay-Differential Equations for Modeling Calcium Cycling in Cardiac Myocytes
... to cardiac modeling at the cellular level and in modeling calcium cycling in cardiac my- ...within cardiac myocytes in detail, emphasizing phenomena like calcium-induced calcium release ...
104
Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardium
... of cardiac muscle and in normal and abnormal murine, rat, and human ...in cardiac myocytes and in coronary microvascular endothelial cells could be enhanced by either LPS or IL-1β, an effect ...
11
Wnt 1 regulation of connexin43 in cardiac myocytes
... neonatal myocytes with lithium, in the form of LiCl, which has been shown previously to inhibit GSK3β (37, ...of cardiac myocytes treated with 20 mM LiCl for 24 hours showed more than a 3-fold ...
12
Engineered Microenvironments for Maturation of Stem Cell Derived Cardiac Myocytes
... of cardiac myocytes remodels its composition during development ...isolated cardiac myocytes have revealed dependence of cellular proliferation [128], survival [129], signaling [130], and ...
17
Neutrophil adherence to isolated adult cardiac myocytes Induction by cardiac lymph collected during ischemia and reperfusion
... examines cardiac-specific lymph collected from awake dogs during 1-h coronary occlusion and 3 d of reperfusion for its ability to induce both ICAM-1 expression in cardiac myocytes, ...
9
CIP4 is required for the hypertrophic growth of neonatal cardiac myocytes
... dissociated cardiac myocytes were separated by centrifu- gation at 50 × g for 1 minute, resuspended in 4 mL horse serum and incubated 37oC with occasional ...of myocytes were repeated 10–12 times to ...
7
Immunolocalization of KATP channel subunits in mouse and rat cardiac myocytes and the coronary vasculature
... We used several antibodies against Kir6.2 subunits to determine their cellular localization. Both the 76A and the G-16 antibodies (Santa Cruz) gave similar results. The W62 antibody developed by us [13] did not seem to ...
18
Peptide growth factors can provoke "fetal" contractile protein gene expression in rat cardiac myocytes
... whether cardiac muscle might be a target for regulation by peptide growth factors, the effect of three growth factors on the actin and myosin gene families was investigated by Northern blot analysis in cultured ...
9
p53 and the hypoxia induced apoptosis of cultured neonatal rat cardiac myocytes
... Previous studies by Tanaka and colleagues (13) have demon- strated that exposure of cultured neonatal cardiomyocytes to hypoxia induces apoptotic cell death. Our results show that these cells, which even at this early ...
10
-induced injury on cardiac myocytes via its target gene HGF
... in cardiac myocytes after treatment with hydrogen peroxide (H 2 O 2 ...-induced cardiac cell apoptosis and over release of creatine kinase (CK) lactate dehydrogenase (LDH) were increased by miR-26b ...
9
Regulation of Ca2+ signaling in transgenic mouse cardiac myocytes overexpressing calsequestrin
... sion of calsequestrin appears to modulate the Ca 21 load of the SR and its physiological release mechanism, suggestive of a dy- namic role for calsequestrin in cellular Ca 21 cycling. Our data further suggest that the ...
10
Sodium channels in cardiac myocytes
... from cardiac myocytes isolated from other amphibian and mammalian hearts, it has been found that cells isolated from either atria or ventricles always have an inwardly rectifying potassium current (Chapter ...
180
Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth
... Heterochromatin assembles not only into large domains of constitutive heterochromatin but can also regulate gene activity on a gene-by-gene basis. For exam- ple, the master cell cycle regulator retinoblastoma protein ...
15
Computational biology of cardiac myocytes: proposed standards for the physiome
... of cardiac models (including our own) (Crampin and Smith, 2006) are guilty of building on existing models without considering the source of all the model ...
8
The Frank–Starling mechanism in vertebrate cardiac myocytes
... in cardiac mechanosensitivity exist within a framework of basic physiological parameters whereby mechanical stimulation increases ...amphibian/fish myocytes appear to be the extended ascending limb of the ...
9
A vascular bed–specific pathway regulates cardiac expression of endothelial nitric oxide synthase
... from cardiac myocytes, skeletal myocytes, and brain ...astrocytes. Cardiac myocyte–mediated induction was partly abrogated by neutralizing anti–platelet- derived growth factor (PDGF) ...
8
Acidosis in models of cardiac ventricular myocytes
... The regulation of pH in excitable tissues has been studied for many decades. The processes regulating pH have been modelled in a variety of tissue and cell types in which pH regulation plays an important role, including ...
17
Temperature acclimation modifies Na+ current in fish cardiac myocytes
... The myocytes of crucian carp and burbot heart were similar in size and clearly smaller than trout ventricular myocytes ...cardiac myocytes. The small cell size (15–30% of the size of mammalian ...
11
Cell cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture
... during cardiac development, remains physiologically relevant in the adult ...in cardiac myocytes, are unknown, as their cells of origin within ventricular ...in cardiac microvascular ...
9