Cardiac Progenitor Cells
ANGPTL8 reverses established adriamycin cardiomyopathy by stimulating adult cardiac progenitor cells
... stem cells, respectively, and the binding of ANGPTLs to these receptors supported ex vivo expansion of hematopoietic stem ...leukemia cells, revealing that PirB supports leukemia ...stem cells and in ...
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Original Article Exercise-induced physiological hypertrophy initiates activation of cardiac progenitor cells
... positive cardiac progenitor cells increased their numbers in exercise-induced physiological ...positive cells in the physiological adaptation of the heart to exercise training is ...positive ...
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Bmi1 + cardiac progenitor cells contribute to myocardial repair following acute injury
... these cardiac progenitor cells ...overload cardiac injury (transverse aortic constric- tion), but not after AMI ...+ cells are the Sca-1 + subset involved in this new CM ...stem ...
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Transplantation of cardiac progenitor cells ameliorates cardiac dysfunction after myocardial infarction in mice
... Cardiac progenitor cells are a potential source of cell therapy for heart ...of cardiac stem/progenitor cells improves function of infarcted hearts, the pre- cise mechanisms of ...
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The epicardium as a source of multipotent adult cardiac progenitor cells: Their origin, role and fate
... identifying cells with the ability to generate new cardiac tissue (reviewed in ...on cardiac function has been lower than was anticipated ...harbours cardiac progenitor cells. ...
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Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction
... increased cardiac fibrosis in the injured heart (40). In lung cancer cells, Tan et ...in cardiac progenitor cells injected in infarcted hearts improves cardiac progenitor ...
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Transplantation of Isl1+ cardiac progenitor cells in small intestinal submucosa improves infarcted heart function
... To further determine the therapeutic effect of SIS- ECM-CPC transplantation, we examined the expression of heart failure markers associated with LV systolic dys- function (Fig. 6). The results of real-time PCR showed ...
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Are Stem Cells the next Therapeutic Tool for Heart Repair?
... (ES) cells, bone marrow (BM) stem cells, myoblasts, fetal cardiomyocytes, endo- thelial progenitors, resident cardiac progenitor cells, and tissue-derived stem cells are ...
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A functional analysis of the role of SHP-2 in vertebrate heart development
... the cells begin to migrate anteriorly and ventrally towards the antero-ventral ...of cells reach the midline the cells fuse to form a single population of cardiac progenitors ...of ...
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MicroRNA-363 negatively regulates the left ventricular determining transcription factor HAND1 in human embryonic stem cell-derived cardiomyocytes
... hESC-derived cardiac progenitor cells and functional CMs, a subset of differentially expressed cardiac miRNAs was identified, and in silico analysis predicted highly conserved binding sites in ...
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Endothelial Dysfunction and Cardiovascular Disease: Critical Target for Cell-Based Therapies
... stem/progenitor cells to regenerate myocardium is a promising treatment therapy for curing damaged cardiac tissue due to heart failure, ischemic heart disease and many other forms of cardiovascular ...
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Disruption of histamine/H1R signaling pathway represses cardiac differentiation and maturation of human induced pluripotent stem cells
... vitro cardiac differentiation from PSCs is simi- lar to heart development involving the primitive streak formation, the specification of the lateral mesoderm, and the generation of cardiac progenitor ...
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Cardiovascular science: opportunities for translating research into improved care
... resident cardiac progenitor cells (34, 38). When such progenitor cells are isolated, cultured, and infused into hearts damaged by ischemia, they home to the injured ...stem ...
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Cardiac Bmi1 + cells contribute to myocardial renewal in the murine adult heart
... myocyte cells termed cardioblasts (CdBs) that express sarcomeric α-actinin (38 %), α-MHC (39 %) and SCA-1 (55 %) but not c-KIT ...formed progenitor pool; they, therefore, appear to arise by ...
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Original Article Absence of myocyte regeneration by mobilization of bone marrow stem cells after myocardial infarction
... stem cells to myocardial infarction ...positive cells in myocardial tissue. But dou- Figure 2. Most Ki67 positive cells (brown nucleus) located at the scar of ...
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Combinatorial treatment of acute myocardial infarction using stem cells and their derived exosomes resulted in improved heart performance
... Fig. 2 Exo and MSCs synergistically improved cardiac function and ameliorated fibrosis after AMI. a Schematic of the sequential delivering of Exo followed by MSCs into the infarcted hearts experiment. b ...
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Adult Cardiac Progenitor Cell Aggregates Exhibit Survival Benefit Both In Vitro and In Vivo
... implanted cells rather the direct differentiation of engrafted ...supplementing cells with soluble survival or anti-apoptotic factors [38], overexpression of proteins involved in survival pathways [39], as ...
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Vascular stem cells in diabetic complications: evidence for a role in the pathogenesis and the therapeutic promise
... endothelial cells (HUVECs), as well as human microvascu- lar endothelial cells (HDMECs) ...these cells non- invasively and in large enough quantities for expansion ex ...the cells can be ...
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Regenerating new heart with stem cells
... spontaneous cardiac repair does not occur after infarction and that necrotic tissue is not restored by intact myocardium (14); instead, the healing process results in a thick ...appropriate cells that ...
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Smoking decreases the level of circulating CD34+ progenitor cells in young healthy women - a pilot study
... of progenitor cells in the circula- tory system of male individuals, and that smoking cessa- tion leads to a rapid elevation in progenitor cell levels ...of progenitor cells in women in ...
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