Cardiac tissues
DNA methylation profiling allows for characterization of atrial and ventricular cardiac tissues and hiPSC-CMs
... with cardiac tissue samples) might be due to the characteristics of in vitro-generated hiPSC-CMs, which are not to be equated with native myocardium and do not show a fully mature phenotype ...[69]. Cardiac ...
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Original Article Effect of emodin on the expression of TLR4 and P38MAPK in mouse cardiac tissues with viral myocarditis
... Mouse cardiac tissues were lysed in lysis buffer, which was then centrifuged to col- lect supernatants, which were quantified by BCA kit. Protein samples were then separated in SDS-PAGE, and were trans- ...
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Maoberry (Antidesma bunius) ameliorates oxidative stress and inflammation in cardiac tissues of rats fed a high fat diet
... Oxidative stress, which occurs because of an imbal- ance between excess free radical formation and low anti- oxidant defense, has unspecific damage to the structure and functions of cells [34]. In the present study, a ...
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Gene expression in cardiac tissues from infants with idiopathic conotruncal defects
... Previously, five patients with TOF were compared to patients with RV hypertrophy, and 88 genes were identi- fied with significantly altered expression in TOF but not altered in RV hypertrophy [14]. The authors listed ...
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Sex-specific modification of progesterone receptor expression by 17β-oestradiol in human cardiac tissues
... Total RNA was isolated from nine male and four female frozen tissues using the Rneasy Fibrous Tissue Mini kit (Qiagen, Hilden, Germany) following the manufacturer ’ s protocol. The RNA quality and quantity was ...
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Pathological pigmentation in cardiac tissues of Atlantic salmon (Salmo salar L.) with cardiomyopathy syndrome
... inflamed cardiac lesions of CMS-diseased fish serve as a protective mechanism against oxidation during cell necrosis followed by repair by scarring in tissue too damaged to be ...
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Detection of enteroviral RNA in idiopathic dilated cardiomyopathy and other human cardiac tissues
... other cardiac conditions (including normal heart), were positive for enteroviral nucleic acid sequences; all eight control cases of breast carcinoma tested were ...
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Adult human cardiac stem cell supplementation effectively increases contractile function and maturation in human engineered cardiac tissues
... healthier cardiac phenotype that is typical of human myo- ...engineered tissues in a biowire format, chronic treatment with electrical stimulation shifted the FFR from flat to positive, which was ...
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Expression profiling of cardiovascular disease
... The availability of cDNA and oligonucleotide microarrays with several thousand human genes makes it possible to study global changes in gene expression in CAD, CHF and CHD . These studies have identified novel genes and ...
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G6PC3, ALDOA and CS induction accompanies mir-122 down- regulation in the mechanical asphyxia and can serve as hypoxia biomarkers
... Hypoxia influences different cellular biological processes. To reveal the dynamics of hypoxia’s effects on miRNA regulation in vivo, we examined the expression levels of all miRNAs in human brain and heart specimens from ...
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Electrospun Polylactic Acid Based Nanofibers for Biomedical Applications
... skin, cardiac tissues, dental and wound healing applications) due to their unique advantages such as high porosity, high surface area to volume ratio, sustainability, biocompatibility and ...
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Endogenous driving and synchronization in cardiac and uterine virtual tissues: bifurcations and local coupling
... excitable tissues The effects of pacemaker size on the ability of that pacemaker to drive surrounding tissue have been examined for various cardiac tissues ...two tissues was distinct, and ...
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Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life
... In conclusion, our present study provides a novel evidence that GDM exposure is one of the important risk factors in the aberrant development of heart ischemia-sensitive phenotype in offspring in gender-dependent manner. ...
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<p>Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats</p>
... Previous studies have demonstrated that mitochondrial dysfunction promotes the production of oxidative free radicals, leading to cardiac oxidative stress in diabetic rats. 26 Overexpression of PGC-1 α in the heart ...
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A modifier screen identifies DNAJB6 as a cardiomyopathy susceptibility gene
... a cardiac muscle cell line derived from adult mouse atrium, were maintained in Complete Claycomb Medium (Sigma Aldrich) supplemented with 100 μM norepinephrine, 4 mM L-glutamine (Sigma Aldrich), and 10% FBS (Sigma ...
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Original Article Cistanche deserticola ethanol extract attenuates left ventricular remodeling and dysfunction by reducing the inflammatory response after myocardial infarction
... the cardiac inflammatory response and prevented adverse remodeling after myocardial infarction (MI) in ...examining cardiac function and ...improve cardiac remodel- ing and dysfunction following MI ...
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Advanced bioreactor system for the implantable biomaterials testing and tissue engineering applications
... Tissue engineering scientists acknowledged that bioreactor system may improve the cell culture stability and function of 3D engineered tissue construct [2, 3]. Furthermore, bioreactors may accelerate the development, ...
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‘Browning’ the cardiac and peri vascular adipose tissues to modulate cardiovascular risk
... the cardiac adipose ...adipose tissues whilst also programming offspring for hypertension in the absence of measureable changes in adiposity or blood ...the cardiac and vascular adipose ...
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The origins and non canonical functions of macrophages in development and regeneration
... whereas cardiac TIMD4 − MPs are almost fully replaced by infiltrating MPs (Dick et ...Whether cardiac MPs are required during normal development is still ...that cardiac MPs are required for the ...
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Allograft Inflammatory Factor 1 in Cardiac Ischemia Re perfusion Injury: Release of Molecular Markers in an in Vitro Setting
... etermine expression levels for AIF-1, TLR-2, T and IL-18, RNA was isolated from peripheral blood mononuclear cells (PBMCs), monocytes and cardiac tis- sue specimens. Briefly, monocytes were isolated from patient’s ...
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