Carrier protein
Characterization and Developmentally Regulated Localization of the Mitochondrial Carrier Protein Homologue MCP6 from Trypanosoma brucei
... mitochondrial carrier protein gene by reciprocal BLAST analysis as a relative of the mitochondrial carrier fam- ily, showing the highest homology to mitochondrial ADP/ATP carriers (AACs) and ...
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Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents
... Recent studies have demonstrated that submicromolar concentrations of the biocide triclosan arrest the growth of the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii and inhibit the activity of the ...
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Identification of B- and T-Cell Epitopes of BB, a Carrier Protein Derived from the G Protein of Streptococcus Strain G148
... (PBS). Protein fractions eluted in the void vol- ume were combined, concentrated by ultrafiltration, and stored at ...for protein with the bicinchoninic acid assay (Pierce) with BSA as a ...
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Depletion of Mitochondrial Acyl Carrier Protein in Bloodstream-Form Trypanosoma brucei Causes a Kinetoplast Segregation Defect
... Acyl carrier protein (ACP), a key player in this pathway, forms a thioester linkage to the growing fatty acyl group and shuttles this molecule between the four enzymes responsible for sequential fatty acid ...
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Improving hydrocarbon production by engineering cyanobacterial acyl-(acyl carrier protein) reductase
... Acyl-(acyl carrier protein (ACP)) reductase (AAR) is a key enzyme for hydrocarbon biosynthesis in cyanobacteria, reducing fatty acyl-ACPs to aldehydes, which are then converted into hydrocarbons by ...
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Screening of Annona muricata for E coli enoyl acyl carrier protein reductase inhibitors by molecular docking
... against various cancers without affecting the normal cells [8]. Ethanolic extract of A. muricata leaves was proven to exhibit apoptosis inducing potential against myelogenous leukemic K562 cells [9-10]. Constituents ...
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Inhibition of the Action of Nonsuppressible Insulin Like Activity on Isolated Rat Fat Cells by Binding to its Carrier Protein
... carrier protein. In this paper we show that partially purified NSILA-S- carrier protein, devoid of endogenous insulin-like activity, inhibits the stimulatory effect of NSILA-S, but not of ...
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Overexpression of Sterol Carrier Protein 2 in Patients with Hereditary Cholesterol Gallstones
... sterol carrier protein 2/nonspecific lipid transfer protein (SCP2/nsLTP) levels by using liver biopsy samples of Japanese patients who had cholesterol gallstones and underwent ...
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ACYL-ACYL CARRIER PROTEIN DESATURASE2 and 3 are responsible for making omega-7 fatty acids in the Arabidopsis aleurone
... Omega-7 monounsaturated fatty acids (v-7s) are specifically enriched in the aleurone of Arabidopsis (Arabidopsis thaliana) seeds. We found significant natural variation in seed v-7 content and used a Multiparent Advanced ...
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The Two Functional Enoyl Acyl Carrier Protein Reductases of Enterococcus faecalis Do Not Mediate Triclosan Resistance
... Enoyl-acyl carrier protein (enoyl-ACP) re- ductases (ENRs) reduce trans-2-enoyl-ACPs to the fully saturated ACP species in the last step of the elongation cycle in the synthesis of bacterial and plant fatty ...
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Engineering acyl carrier protein to enhance production of shortened fatty acids
... acyl carrier protein (ACP), an essential protein and key compo- nent of fatty acid ...4.1) protein abun- dant in the cytoplasm, constituting about ...
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Discrimination of Potent Inhibitors of Toxoplasma gondii Enoyl-Acyl Carrier Protein Reductase by a Thermal Shift Assay
... Many microbial pathogens rely on a type II fatty acid synthesis (FASII) pathway which is distinct from the type I pathway found in humans. Enoyl-Acyl Carrier Protein Reductase (ENR) is an essential FASII ...
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Recombinant Group B Streptococcus Alpha-Like Protein 3 Is an Effective Immunogen and Carrier Protein
... We have recently demonstrated that a recombinant BCP and a recombinant BCP modified to eliminate its human IgA- binding site (rBCP ⌬IgA ) were not only effective immunogens but also strong carriers for the type III CPS, ...
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Sterol carrier protein-x gene and effects of sterol carrier protein-2 inhibitors on lipid uptake in Manduca sexta
... sterol carrier protein-2 (SCP-2)-like proteins [18,23,24], in contrast to the single copy of the SCP-x/SCP-2 gene in vertebrates [25,26] and in the silk- worm, ...SCP-2 protein which is not produced ...
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3-D QSAR CoMFA Models of Pyrrolidine carboxamides for Prediction of Enoyl acyl carrier protein reductase Inhibitory Activity
... The predictive 3D-QSAR models were generated for the training sets of Enoyl acyl carrier protein reductase inhibitors using default parameters of COMFA, as determined by cross validation. Reliability of the ...
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A critical evaluation of structure, mechanism and functions of riboflavin carrier protein
... the protein are encountered as early as day 4 of gestation with peak levels being attained between days ...vitamin carrier protein that may participate in flavin transport from the maternal supply ...
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Effect of Increased CRM197 Carrier Protein Dose on Meningococcal C Bactericidal Antibody Response
... tantly administered infant vaccines in other geographic regions, or another dosing schedule. Observed differences in MenC antibody response could be due to the use of two MenC-CRM vaccines with different conjugation ...
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Cloning and Enzymatic Activity Analysis of the Malonyl CoA:acyl Carrier Protein Transacylase in Brassica napus Cultivars with Different Oil Content
... malonyl-CoA:acyl carrier protein transacylase (MCAT), a key enzyme in the FAS II pathway, is respon- sible for transferring the malonyl group from malonyl-CoA (malonyl-coenzyme A) to the -SH group of ACP ...
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Defective glycine cleavage system in nonketotic hyperglycinemia Occurrence of a less active glycine decarboxylase and an abnormal aminomethyl carrier protein
... aminomethyl carrier protein (H-protein), two of the four protein components of the glycine cleavage system, were considerably reduced in both the liver and brain; the extent of reduction was ...
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Arabidopsis acyl-acyl carrier protein synthetase AAE15 with medium chain fatty acid specificity is functional in cyanobacteria
... target protein was eluted with the solubilization buffer containing 100 mM ...assays. Protein concentration in the sample of the purified protein was not ...
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