cartilage defects
Original Article Comparative evaluation of leukocyte- and platelet-rich plasma and pure platelet-rich plasma for cartilage regeneration in a cartilage defects model in rabbits
... rabbit cartilage defects ...International Cartilage Regeneration Society (ICRS) macroscopic scores, micro- computed tomography scanning, and histological observation according to ICRS histological ...
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Full thickness cartilage defects are repaired via a microfracture technique and intraarticular injection of the small molecule compound kartogenin
... However, many researchers have observed that the long- term results after microfracture are poor and that micro- fracture is limited in treating cartilage defects in elderly patients. Von Keudel et al. [8] ...
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Ongoing studies of cell-based therapies for articular cartilage defects in Japan
... In this update on the latest cell-based therapies conducted in Japan, we focus on various treatment options for articular cartilage injury. None of the new treatments reported direct adverse events in registered ...
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Treatment of focal degenerative cartilage defects with polymer based autologous chondrocyte grafts: four year clinical results
... in cartilage repair. In a goat model, it has been shown that defects showed better repair when the lesion was covered immediately with periosteum compared with defects that were left untreated before ...
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Rabbit articular cartilage defects treated with cultured costal chondrocytes (preliminary report)
... costal cartilage started in the ...costal cartilage is col- lected from and on the unknown but necessary host ...reconstruct cartilage after trans- plantation into the soft ...costal cartilage ...
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Interleukin 6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model
... Although cartilage pathology seemed to clearly affect IL- 6 production and at least part of the response to interfer- ence with this factor, several other donor-related factors may have additionally influenced the ...
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Association of childhood adiposity measures with adulthood knee cartilage defects and bone marrow lesions: a 25 year cohort study
... of cartilage defects may be susceptible to artefacts resulting from calci fi cations within the cartilage, but it has been validated as accurate and reproducible 52 , and has been used in ...
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Tibial subchondral bone size and knee cartilage defects: relevance to knee osteoarthritis
... bone defects are more likely to have knee pain in the presence of radiographic OA ...knee cartilage defects alon e were significantly associated with knee pain in a dose-response fashion in a younger ...
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Strain distribution of repaired articular cartilage defects by tissue engineering under compression loading
... focal defects of articular cartilage has been predicted theoretically and ana- lyzed experimentally in in vitro systems, few reports focus on what the mechanical condition is after repairing ...
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Clinical and cost effectiveness of autologous chondrocyte implantation for cartilage defects in knee joints : systematic review and economic evaluation
... proportion of patients with complications within 24 months after ACI and after OCT [12/20 (60%) with ACI versus 12/20 (60%) with OCT]. Seven patients had complications after ACI that required further surgery. These ...
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A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose
... After reaching the required amount of cells, high-density cultures of chondrocytes isolated by ‘ outgrowth-cultures ’ from the BNC and cartilage surface and after enzymatic digestion of cartilage were ...
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Mesenchymal stem cells in the treatment of traumatic articular cartilage defects: a comprehensive review
... Articular cartilage has a limited capacity to repair following ...osteochondral defects to advanced cartilage degeneration and ...resurfacing defects with bioengineered tissue that ...
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Change in knee structure and change in tibiofemoral joint space width: a five year longitudinal population–based study
... greater cartilage loss in the other compart- ...in cartilage volume, and new or worsening meniscal extrusions, meniscal tears, and cartilage defects over ...
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Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian Older Adult Cohort (TASOAC) study
... knee cartilage volume and BMI (or body fat mass) were also investigated by linear regression after adjustment for ...knee cartilage defects and log transformed leptin/ BMI/body fat ...
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Tibiofemoral joint structural change from 2 5 to 4 5 years following ACL reconstruction with and without combined meniscal pathology
... including cartilage volume, cartilage defects and bone marrow lesions (BMLs) [10, ...TFJ cartilage volume and/or thickness from 1 to 5 years following ACL injury, with these being more ...
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Associations between MRI detected early osteophytes and knee structure in older adults: a population based cohort study
... Associations of baseline osteophytes phenotypes with increases in total knee cartilage defects a, change in cartilage volume b, and increases in BMLs c.. OP: osteophytes; MTF: medial tib[r] ...
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Infrapatellar fat pad and knee osteoarthritis
... intensity. Cartilage volume and defects, and BMLs were assessed using validated ...tibial cartilage volume and larger increases in tibiofemoral cartilage defects over 2 ...of ...
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Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
... of cartilage repair by synovial mesenchymal stem cell transplantation in ...a cartilage defect in a rabbit by the local adherent ...of cartilage defects after cell ...the cartilage ...
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Correlates of knee bone marrow lesions in younger adults
... Subchondral bone is richly innervated with nociceptive pain fibres [45]. Thus, subchondral bone could be a source of knee pain. There is increasing evidence to sug- gest that BMLs are associated with knee pain [4, 46–48] ...
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The Use of Human Amniotic Membrane for Cartilage Repair: A Sheep Study
... Two cartilage defects were created using curettes: one on the weight-bearing surface of the femoral condyle and one in the trochlear ...The defects did not penetrate the subchondral ...the ...
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