Cartilage repair
A retinaculum-sparing surgical approach preserves porcine stifle joint cartilage in an experimental animal model of cartilage repair
... assessing cartilage repair methodologies such as using tissue engineered biomaterial to fill focal defects, as the entire joint environment is ...of cartilage wear were noted when animals were ...
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Translational applications of photopolymerizable hydrogels for cartilage repair
... cartilage repair, regeneration, or replacement, they must be surgically adapted to the cartilage defect, with ap- proximately 6 weeks of partial weightbearing to support for the biological switch to ...
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Engineered Fibrous Hyaluronic Acid Hydrogels for Cartilage Repair
... is cartilage repair. Mature hyaline cartilage is avascular and alymphatic, with cells comprising only about 5% of the tissue volume ...articular cartilage usually leads to progressive tissue ...
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TGF β induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7
... articular cartilage organ ...of cartilage in ...boost cartilage repair in ...on cartilage PG synthesis and PG ...damaged cartilage by IL-1 injection and subsequently ...
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Cartilage Repair by Joint Distraction and Motion Using an External Fixator for Massive Cartilage Defect
... the repair of massive cartilage defects by joint distraction and motion using an external ...articular cartilage defect in order to evaluate the effectiveness of using joint distraction and motion ...
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Hypoxia HIF mediated articular chondrocyte function: prospects for cartilage repair
... in cartilage pathology, such as osteoarthritis ...for cartilage repair ...Articular cartilage is under two perma- nent stresses, mechanical and ...to cartilage are potent regulators of ...
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An ex vivo human cartilage repair model to evaluate the potency of a cartilage cell transplant
... treat cartilage defects include autol- ogous chondrocyte implantation ...of cartilage cell trans- plant properties before implantation and their potency to regenerate cartilage tissue after ...human ...
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Development and characterisation of a decellularised bovine osteochondral biomaterial for cartilage repair.
... acellular cartilage and osteochondral scaffolds for use in cartilage lesion repair ...engineered cartilage repair materials, due to the presence of the subchondral ...
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Pullulan: a new cytoadhesive for cell-mediated cartilage repair
... diseased cartilage surface with the intention of increasing MSC therapeutic ...the cartilage surface as hypothesised owing to its chosen phys- ical properties as a wet stick ...
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The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review
... There has also been a further step taken to avoid bone marrow harvest in which peripheral blood has been used in knee chondral lesions. In an RCT, arthroscopic sub- chondral drilling was followed by postoperative intra- ...
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Use of mesenchymal stem cells seeded on the scaffold in articular cartilage repair
... articular cartilage, indicating that MSCs are proper tool for implantation to repair the articular cartilage ...articular cartilage repair ...the repair of articular ...
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Biology of platelet rich plasma and its clinical application in cartilage repair
... fill cartilage lesions, fulfilling the initial requirements of physiological wound ...fill cartilage defects with variable results, or to slow the progression of arthritis in animal models with positive ...
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Blocking aggrecanase cleavage in the aggrecan interglobular domain abrogates cartilage erosion and promotes cartilage repair
... for cartilage biomechanics because it releases the entire CS-containing portion of ...mouse cartilage have not distinguished aggrecanolysis in the IGD from aggre- canolysis in the CS-2 ...to ...
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One-stage vs two-stage cartilage repair: a current review
... of cartilage repair being performed, malalignment, ligamentous/meniscal deficiency, and subchondral bone loss should be corrected to create an environment conducive to cartilage ...
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Articular cartilage repair and the evolving role of regenerative medicine
... articular cartilage repair has now been used for 2 decades and forms a successful example of translational ...medicine. Cartilage is characterized by a limited intrinsic repair capacity ...
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Autologous chondrocyte implantation for cartilage repair: current perspectives
... index cartilage treatment an arthroscopy of the left knee was ...different repair mechanisms of the specific cartilage ...treated cartilage defect of the medial femoral condyle ...after ...
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Mesenchymal stem cells for cartilage repair in osteoarthritis
... for cartilage repair have been shown to produce acceptable clinical ...articular cartilage in patients with OA is not clear, the ability of these cells to induce proliferation and differen- tiation ...
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Effects of microcurrent stimulation on Hyaline cartilage repair in immature male rats (Rattus norvegicus)
... The cartilage repair area was determined on the digi- tized images as percent reduction of the original ...the repair tissue (%), respectively, in the two ...
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3D-bioprinting a genetically inspired cartilage scaffold with GDF5-conjugated BMSC-laden hydrogel and polymer for cartilage repair
... In the present study, we report genome-wide association between GDF5 gene and DDH with the largest combined GWAS and follow-up replications in multiple populations, identifying multiple loci and genomic regions spanning ...
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International Cartilage Repair Society
... patients with severe ankle OA who are treated with joint distraction, radiographic subchondral sclerosis diminished while joint space width increased, the latter suggesting cartilage repair 7 . However, the ...
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