cationic liposomes
Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice
... of cationic lipo- ...whether cationic liposomes associate with angiogenic vessels by virtue of binding and uptake by endothelial cells or by virtue of ex- ...fluorescent liposomes and ...
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Higly fusogenic cationic liposomes transiently permeabilize the plasma membrane of HeLa cells
... Abstract: Cationic liposomes can efficiently carry nucleic acids into mammalian ...diC14-amidine liposomes displayed a much higher susceptibility to lipid mixing with the target ...diC14-amidine ...
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Enhanced localization of anticancer drug in tumor tissue using polyethylenimine conjugated cationic liposomes
... DSPE-PEI cationic liposomes was found to result in significantly increased in vitro intracellular uptake compared with control ...drug-loaded liposomes at the tumor site through electrostatic ...
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Arginine-based cationic liposomes for efficient in vitro plasmid DNA delivery with low cytotoxicity
... of cationic liposomes a and b was investigated by loading the lipoplexes onto a 1% agarose gel (Takara Bio, Otsu, Japan) pre-stained with ethidium ...of liposomes containing various amounts of ...
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Mechanisms of Enhanced Antigen Delivery to Murine Dendritic Cells by the Cationic Liposomes
... the cationic liposome to ...the cationic liposomes increased the cellular uptake to ...like liposomes with cell membrane plays a significant role in the endocytic ...instance, cationic ...
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Cationic Liposomes: A Flexible Vaccine Delivery System for Physicochemically Diverse Antigenic Peptides
... the cationic liposomes, we made use of the previously optimized dehydration- rehydration protocol for SLP encapsulation ...DOTAP:DOPC liposomes loaded with the so-called “OVA24” SLP, harboring the ...
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Cationic liposomes promote antigen cross-presentation in dendritic cells by alkalizing the lysosomal pH and limiting the degradation of antigens
... Abstract: Cationic liposomes (CLs) have been widely examined as vaccine delivery nanoparticles since they can form complexes with biomacromolecules, promote delivery of antigens and adjuvant molecules to ...
14
Intranasal administration of cationic liposomes enhanced granulocyte–macrophage colony stimulating factor expression and this expression is dispensable for mucosal adjuvant activity
... the cationic liposomes (unpublished ...onic liposomes in this study and found that GM-CSF blocking did not affect their activities, clearly indicating that other soluble factors control the mucosal ...
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Cationic Liposomes Enhance the Rate of Transduction by a Recombinant Retroviral Vector In Vitro and In Vivo
... The data presented here show that both Polybrene and DC- Chol/DOPE enhanced the rate of retroviral transduction. The initial rate enhancement was approximately 10- and 20-fold, respectively. The correlation of MOI with ...
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Targeting of small molecule anticancer drugs to the tumour and its vasculature using cationic liposomes: lessons from gene therapy
... Modern medicine is successful in achieving disease-free survival in a good number of cancer patients. However, in a majority of cases, medical intervention is only successful in prolonging the life of a patient from ...
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Cationic Liposomes Extend the Immunostimulatory Effect of CpG Oligodeoxynucleotide against Burkholderia pseudomallei Infection in BALB/c Mice
... Melioidosis is a severe disease caused by the Gram-negative bacterium Burkholderia pseudomallei. Previously we showed that pretreatment of mice with CpG oligodeoxynucleotide (CpG ODN) 2 to 10 days prior to B. ...
9
Insights into the therapeutic potential of hypoxia-inducible factor-1α small interfering RNA in malignant melanoma delivered via folate-decorated cationic liposomes
... Figure 4 shows the electrophoresis phenomena of naked HIF-1 α siRNA and its liposome complexes with different treatments. It could be seen that HIF-1 α siRNA has been effectively loaded onto the cationic ...
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Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis
... as cationic liposomes (CLs) can protect drugs from being degraded in the body before they reach their target, and allow for better control over the timing and distribution of drugs to tumor tissue ...date, ...
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<p>Co-Delivery Of Dihydroartemisinin And HMGB1 siRNA By TAT-Modified Cationic Liposomes Through The TLR4 Signaling Pathway For Treatment Of Lupus Nephritis</p>
... peptide-cationic liposomes (TAT-CLs) to deliver anti-HMGB1 siRNA and dihydroartemisinin (DHA) to increase LN ther- apeutic ef fi ciency and explore their treatment ...
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Zwitterionic Poly(carboxybetaine)-based Cationic Liposomes for Effective Delivery of Small Interfering RNA Therapeutics without Accelerated Blood Clearance Phenomenon
... the cationic liposomes were sized by repeated extrusion through EmulsiFlex-C5 high-pressure ho- mogenizer (Avestin, ...mixing cationic liposomes with siRNA together at designed N/P ratios at ...
14
<p>Preparation And Antibacterial Effects Of Carboxymethyl Chitosan-Modified Photo-Responsive <em>Camellia</em> Sapogenin Derivative Cationic Liposomes</p>
... the cationic surfactant CTAB is a quaternary ammonium salt, easily leads to hemolysis with cytotoxicity, 39 the safety of PCC liposomes was preliminarily evaluated by erythrocyte ...PCC liposomes was ...
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Preparation, characterization, and efficient transfection of cationic liposomes and nanomagnetic cationic liposomes
... magnetic cationic liposomes (MCLs) were prepared using the freeze-dried empty liposome ...into liposomes and the transfection efficiencies were determined by luciferase ...of liposomes have ...
9
pH-Sensitive carboxymethyl chitosan-modified cationic liposomes for sorafenib and siRNA co-delivery
... through 400, 200, and 100 nm polycarbonate membranes for five cycles, respectively, using a LiposoFast™ basic extruder (Avestin, Ottawa, ON, Canada). To incorporate siRNA, Sf-CL were simply mixed with siRNA solution (20 ...
14
Cationic liposomes (Lipofectin) mediate retroviral infection in the absence of specific receptors.
... To quantitatively demonstrate the effectiveness of Lipofectin in allowing retrovirus infection in nonpermissive cells, we exposed CCL 64 mink lung fibroblasts 11 to the ecotropic package[r] ...
5
Introduction of hepatitis delta virus into animal cell lines via cationic liposomes.
... As reported here, we have been able to use such a commercially available formulation Lipofectamine and introduce human hepatitis delta virus HDV into lines of cultured cells and demonstr[r] ...
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