Caveolin-1 (Cav-1)
Hepatic caveolin 1 is enhanced in Cyp27A1/ApoE double knockout mice
... atherosclerosis. Caveolin-1 (CAV-1), the main component of caveolae, is associated with lipid homoeostasis and has regulatory roles in vascular ...liver CAV-1 would contribute to ...
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<p>Association of caveolin-1 protein expression with hepatocellular carcinoma: a meta-analysis and literature review</p>
... searching: caveolin- 1 or CAV-1 and HCC, liver cancer or ...criteria: 1) the association between CAV-1 overexpression and clinicopathological signi fi cance in HCC; 2) the ...
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Hepatitis B Virus Requires Intact Caveolin-1 Function for Productive Infection in HepaRG Cells
... component, caveolin-1 (Cav-1), in HBV ...dominant-negative Cav-1 and dynamin-2, a GTPase involved in vesicle formation at the plasma membrane and other ...HepaRG ...
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Blockade of Human Immunodeficiency Virus Type 1 Expression by Caveolin-1
... human Cav-1 with human immunodeficiency virus type 1 (HIV-1) blocked virion produc- tion from cells that are ordinarily highly ...of Cav-1 to HIV-1 DNA, depends on ...
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Molecular control of nitric oxide synthesis through eNOS and caveolin-1 interaction regulates osteogenic differentiation of adipose-derived stem cells by modulation of Wnt/β-catenin signaling
... and caveolin-1 (CAV-1 WT and CAV-1 F92A ) expression in eASCs was performed as ...for 1 h and coun- terstained with DAPI for nuclear staining (Sigma-Al- ...and ...
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Lipopolysaccharide-induced caveolin-1 phosphorylation-dependent increase in transcellular permeability precedes the increase in paracellular permeability
... in caveolin-1 (Cav-1) expression in endothelial cells; however, the mechanisms regarding this response and the con- sequences on caveolae-mediated transcellular transport have not been ...
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Caveolin-1 in sarcomas: friend or foe?
... Caveolin-1 (CAV1) belongs to a family of proteins named caveolins. There are three members: CAV1, 2 and 3, which can form homo- and hetero-oligomeric complexes mediated by domains in the N- and C-terminal ...
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Caveolin 2 associates with intracellular chlamydial inclusions independently of caveolin 1
... that caveolin-1/2 hetero- oligomers traffic to the plasma membrane from the Golgi [25,26,30,31], it is reasonable to suggest that the previ- ously described pathogen induced interception of Golgi- derived ...
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Caveolin 1 expression in benign and malignant lesions of the breast
... no Caveolin-1 expression at all (staining score 0) were defined as "Caveolin-1 negative", whereas weakly, moderately and strongly stained tissue cores were taken together as ...
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Loss of parkin promotes lipid rafts-dependent endocytosis through accumulating caveolin-1: implications for Parkinson’s disease
... murine caveolin-1 forward, 5′- CGT AGA CTC CGA GGG ACA TC-3′ and reverse, 5′- TCC CTT CTG GTT CTG CAA TC -3′; murine caveolin-2; forward, 5′- CTC AAG CTA GGC TTC GAG GA-3′ and reverse, 5′- GCA AGA ...
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Disruption of the maxi-K-caveolin-1 interaction alters current expression in human myometrial cells
... the caveolin-1 gene was inhibited (see siRNA) were placed in a pH ...KCl, 1 MgCl 2 , 10 Glucose, 2 CaCl 2 and 5 ...MgCl2, 1 EGTA, 5 ATP and 5 ...
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Deletion of integrin linked kinase in endothelial cells results in defective RTK signaling caused by caveolin 1 mislocalization
... subcellular caveolin 1 ...of caveolin 1 in close vicinity of the plasma membrane; these findings also support those recently reported in keratinocytes (Wickström et ...of caveolin ...
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Expression and clinical significance of Caveolin-1 in prostate Cancer after transurethral surgery
... does caveolin-1 lose its inhibitory function as a tumor suppressor and instead promote tumor growth? It is generally believed that the mechanism of action may have three points: 1) point mutations ...
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Evaluation of caveolin-1 expression in different grades of oral epithelial dysplasia
... of caveolin-1 expression in the ductal epithelial cells in all 20 normal salivary gland ...of caveolin-1 was noted in 34 samples ...Down-regulated caveolin-1 expression was ...
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Caveolin-1 expression is elevated in claudin-low mammary tumor cells
... in Cav-1 following the analysis of DNA microarray results that compared mam- mary tissue from wild type mice to tumor tissue from transgenic mice that express elevated levels of the type I insulin-like ...
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Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL
... (forward:5 ′ -AGT TGT CAT GGA TGA CCT TGG C-3 ′ ; reverse:5 ′ -ATC ACC ATC TTC CAG GAG CGA- 3 ′ ), SNAIL (forward:5 ′ -TCG GAA GCC TAA CTA CAG CGA-3 ′ ; reverse:5 ′ -AGA TGA GCA TTG GCA GCG AG-3 ′ ), Cav-1 ...
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Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer
... Data were summarized using descriptive statistics and exploratory graphics such as bar plots. For the in vitro experimental data unpaired t-tests were performed to compare between the treatment groups. In the experiments ...
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Promotion of human mesenchymal stem cell osteogenesis by PI3-kinase/Akt signaling, and the influence of caveolin-1/cholesterol homeostasis
... fluoride (PVDF) blots which were blocked in 5 % milk or 5 % bovine serum albumin (BSA; Sigma-Aldrich) in Tris- buffered saline + 0.05 % Tween 20 (TBST), and then incu- bated overnight at 4 °C with either rabbit anti-Akt ...
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Caveolin-1, a stress-related oncotarget, in drug resistance
... that Cav-1 knockdown could enhance human MSC osteogenesis, and bone marrow MSCs from the Cav-1 knockout mice had greater osteogenic potential ...[106]. Cav-1 null mouse mammary ...
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Bovine Papillomavirus Type 1: from Clathrin to Caveolin
... of caveolin-1, we wanted to determine whether the caveolar ligand CTB was blocked from entering cells expressing shRNA against caveolin-1 ...of caveolin-1 expression results in a ...
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