Caveolin-1/Caveolae
Influence of cholesterol/caveolin-1/caveolae homeostasis on membrane properties and substrate adhesion characteristics of adult human mesenchymal stem cells
... and caveolin-1 (CAV-1) perturbation on caveolae content in ...12). Caveolae are identified on the basis of CAV-1 content. a CAV-1 immunoblotting of the ...file 1: ...
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The less-often-traveled surface of stem cells: caveolin-1 and caveolae in stem cells, tissue repair and regeneration
... of caveolin-1 expres- sion in MSCs decreases mRNA expression of the pluripotency marker POU5F1/Oct4 (unpublished observa- tions), and others have found that caveolin-1 expression and ...
13
Direct evidence for the role of caveolin 1 and caveolae in mechanotransduction and remodeling of blood vessels
... endothelial caveolae and is necessary for caveolae ...of caveolae organelles in blood vessels, adipocytes, and fibroblasts obtained from Cav-1–deficient mice (2, ...In caveolae, ...
9
Caveolin-1 in sarcomas: friend or foe?
... named caveolae [43, ...CAV1, caveolae are not morphologically distinguishable suggesting a non-caveolar role for ...a caveolae-independent role of CAV1 as a molecular ...of caveolae-like ...
8
Internalization of Echovirus 1 in Caveolae
... against caveolin-1; rabbit antiserum against the cation-independent mannose 6-phosphate receptor (CI-MPR) (21); rabbit antisera (GB2) against trans-Golgi network protein 46 (TGN-46) (4), p23 (34), and early ...
10
A Role for Caveolin 1 in Assembly and Budding of the Paramyxovirus Parainfluenza Virus 5
... in caveolae. In addition, Cav-1 staining was observed within newly budded virions ...the caveolin-binding motif found in the M sequence is conserved within the Rubulavirus genus ...
11
Caveolin 2 associates with intracellular chlamydial inclusions independently of caveolin 1
... that caveolin-2 is not trans- ported out from the Golgi in caveolin-1 negative FRT cells, but that expression of a transfected caveolin-1 gene in those cells restores caveolin-2 ...
12
Deletion of integrin linked kinase in endothelial cells results in defective RTK signaling caused by caveolin 1 mislocalization
... 2010b). Caveolae are present in most cell types, but are particularly abundant in ECs and are known to play a crucial role in EC biology (Cho et ...of caveolae in ECs is caveolin 1 and this ...
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Heparan Sulfate-Binding Foot-and-Mouth Disease Virus Enters Cells via Caveola-Mediated Endocytosis
... O 1 Campos enters the cell in an early endosome, followed by movement into a recy- cling endosome, where the virus breaks down due to the acidic environment, releasing the RNA ...O 1 Campos and O 1 ...
11
Blockade of Human Immunodeficiency Virus Type 1 Expression by Caveolin-1
... Caveolin-1 (Cav-1) is a major protein constituent of caveolae, a type of plasma membrane raft. We observed that coexpression of human Cav-1 with human immunodeficiency virus type ...
13
Entry of sapelovirus into IPEC J2 cells is dependent on caveolae mediated endocytosis
... CME, caveolae, and lipid rafts [23, ...of caveolin-1, Eps15 and ...was caveolin-, lipid raft-, and dynamin-dependent and did not involve the clathrin and macropinocytosis ...
8
Caveolin 1 expression in benign and malignant lesions of the breast
... of Caveolin-1 in mammary carcinogenesis is still far from being completely ...of Caveolin-1 in breast can- cer supported by some researchers [26] is contrasted by recent results which ...
9
Injury induced expression of caveolar proteins in human kidney tubules - role of megakaryoblastic leukemia 1
... of caveolae in smooth ...of caveolin-1/CAV1 and other caveolar proteins in atrophic proximal tubules and in tubular cells in primary ...of caveolin-1/CAV1 and PTRF/CAVIN1 significantly ...
15
Promotion of human mesenchymal stem cell osteogenesis by PI3-kinase/Akt signaling, and the influence of caveolin-1/cholesterol homeostasis
... and caveolae rafts. Intracellular cholesterol levels and Cav-1/caveloae activity are directly, functionally linked; an increase in intracellular cholesterol levels promotes Cav-1-directed cholesterol ...
11
Role of caveolin 1 in the regulation of the vascular shear stress response
... forces. Caveolae — 50- to 100-nm plasma membrane invaginations present at the surface of terminally differentiated cells and particularly enriched in ECs — are composed of a high sphingolipid ...
5
Caveolin-1, a stress-related oncotarget, in drug resistance
... within caveolae, including EGFR, PDGFR, H-Ras, Raf kinase, ERK1/2 kinases, Shc and Grb ...Cav- 1 overexpression inhibited Ras-p42/44 MAPK signaling by acting as an endogenous inhibitor of EGFR, MEK- ...
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Expression of Caveolin-1 in Verrucous Carcinoma and in Oral Squamous Cell Carcinoma
... type 1 (MT1)-MMP colocalizes with caveolae and Cav-1. Cav-1 may function as a negative regulator by inhibiting MT4-MMP expression, which is associated with the metastasis in colon ...
92
Caveolae and Caveolin: Potential Targets for Cardioprotection
... of caveolae and caveolin in the regulation of many cellular processes in cultured cells and many investigators considered them as an essential platform of signaling ...of caveolin-1 or ...
13
Evaluation of caveolin-1 expression in different grades of oral epithelial dysplasia
... type 1 (MT1)-MMP colocalizes with caveolae and Cav-1. Cav-1 may function as a negative regulator by inhibiting MT4-MMP expression, which is associated with the metastasis in colon ...
97
HIV Infection Upregulates Caveolin 1 Expression To Restrict Virus Production
... examined Sp1’s possible role in Tat-mediated Cav-1 upregula- tion. U87-CD4-CXCR4 cells were pretreated with siRNA to knock down the expression of Sp1, which was followed by transfection of the tat-expressing ...
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