CCL2/MCP-1
5, 8, 11, 14-eicosatetraynoic acid suppresses CCL2/MCP-1 expression in IFN-γ-stimulated astrocytes by increasing MAPK phosphatase-1 mRNA stability
... the MCP-1 promoter is increased in ETYA-treated group as compared to IFN-g- treated ...affect MCP-1 gene expression (Additional file 2: Figure ...suppressed CCL2/MCP-1 ...
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Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes
... Like CCL2, CXCL8 is produced by a variety of cell types and is induced by proinflammatory mediators like endotoxin ...is CCL2 (MCP-1) and several studies suggest that CCL2 is the main ...
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CCL2/MCP-1 modulation of microglial activation and proliferation
... (CCL2/ MCP-1) is one of the main chemokines regulating microglial movement, it was our goal to study here some of the effects MCP-1 has on isolated microglia, and to determine if the ...
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Helck, Andreas (2007): Der Einfluss des partiellen MCP-1/CCL2-Antagonisten [18AA19]-MCP-1 auf den Verlauf der experimentellen Autoimmunuveitis. Dissertation, LMU München: Medizinische Fakultät
... Chemokin MCP-1/CCL2, welchem wegen seiner chemotaktischen Aktivität ...endogenen MCP-1/CCL-2 durch Verabreichung des Rezeptorantagonisten [ 18 AA 19 ]-MCP-1 inhibiert ...
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Spiral ligament fibrocyte derived MCP 1/CCL2 contributes to inner ear inflammation secondary to nontypeable H influenzae induced otitis media
... cing MCP-1/CCL2 expression, based on our previous data showing that SLFs released high levels of MCP-1/ CCL2 upon exposure to the OM pathogens ...rat MCP-1-specific ...
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Hypoxia-inducible factor-1 (HIF-1) is involved in the regulation of hypoxia-stimulated expression of monocyte chemoattractant protein-1 (MCP-1/CCL2) and MCP-5 (Ccl12) in astrocytes
... Ischemic brain damage, including that caused by stroke and trauma, elicits inflammation in the injured areas [1- 3]. A number of inflammatory mediators are expressed in the brain in response to ischemia and ...
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Peripheral blood mononuclear cells from neovascular age-related macular degeneration patients produce higher levels of chemokines CCL2 (MCP-1) and CXCL8 (IL-8)
... IL-8 (CXCL8), an important inflammatory cytokine and potent angiogenic factor, has previously been linked to the pathogenesis of AMD. Single-nucleotide poly- morphisms (SNPs) in the IL-8 regulatory and coding regions ...
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Different actions of endothelin-1 on chemokine production in rat cultured astrocytes: reduction of CX3CL1/fractalkine and an increase in CCL2/MCP-1 and CXCL1/CINC-1
... the damaged areas. In addition to vascular endothelial cells, expression of chemokine receptors in normal and patho- logical brains were shown in neurons, astrocytes and microglia [1], suggesting that the function ...
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The role of PPARγ in carbon nanotube-elicited granulomatous lung inflammation
... Total RNA was extracted from total BAL cells by RNeasy protocol (Qiagen, Valencia, CA). Expression of mRNA was determined by real time qPCR using the ABI Prism 7300 Detection System (TaqMan; Applied Biosystems, Foster ...
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Systemic inflammatory response syndrome in a patient diagnosed with high grade inflammatory triple negative breast cancer: a case report of a potentially rare paraneoplastic syndrome
... protein 1; CCL3/MIP1A: chemokine (C–C motif ) ligand 3/macrophage inflammatory protein 1‑alpha; CCL5/RANTES: chemokine (C–C motif ) ligand 5/regulated on activation, normal T cell expressed and secreted; ...
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A standardized model of brain death, donor treatment, and lung transplantation for studies on organ preservation and reconditioning
... chemokines CCL2- MCP-1 and IL-8 as well as increased transcription of SELE at different phases of the transplantation process suggest the presence of an inflammatory reaction ...
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MCP-1/CCL2 in a Bulgarian cohort of children with
... childhood asthma; bronchial asthma; severe asthma; cystic fibrosis; chronic obstructive pulmonary 32.. disease.[r] ...
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Tropism of mesenchymal stem cell toward CD133+ stem cell of glioblastoma in vitro and promote tumor proliferation in vivo
... for MCP-1/CCL2 and SDF-1/CXCL12, and demonstrated, in vitro, that MCP-1/CCL2 and SDF-1/CXC12, secreted by CD133 + GBM cells from primary cell cultures, induce the ...
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Chemokine mediated recruitment of NK cells is a critical host defense mechanism in invasive aspergillosis
... anti-murine MCP-1/CCL2 Ab (2H5) was used for in vivo neutralization experiments (5, ...and MCP-1/CCL2–neutralizing activity was deter- mined by ...anti-murine ...
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Modified Vaccinia Virus Ankara Triggers Chemotaxis of Monocytes and Early Respiratory Immigration of Leukocytes by Induction of CCL2 Expression
... as CCL2 (monocyte chemotactic protein-1 ...of CCL2, CCL3, CCL4, and CXCL10 in the human monocytic cell line THP-1 as well as in primary human ...including CCL2, in the murine lung, ...
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Inhibition of Microbially-induced Inflammation by the Naturally Occurring Plant Compounds Tetra-O-methyl nordihydroguaiaretic acid (terameprocol) and Berberine.
... TNF-α, MCP-1/CCL2, G-CSF, and several prostaglandins, while modestly inhibiting the production of IL-6 and ...TNF-, MCP- 1/CCL2, and RANTES/CCL5 promoters despite its inability ...
170
CCR2 and CXCR3 agonistic chemokines are differently expressed and regulated in human alveolar epithelial cells type II
... of CCL2 mRNA in vitro and in situ , and released CCL2 protein in vitro ...both CCL2 mRNA expression and release of immunoreactive CCL2, whereas IFN- γ had no effect on CCL2 ...the ...
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Monocyte chemoattractant protein 1 promotes macrophage mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis
... whether MCP-1 promotes tubular and/or glomerular injury, we induced nephro- toxic serum nephritis (NSN) in MCP-1 genetically deficient ...the MCP-1–intact strain (day 7). ...
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Optimization of Ethylene inhibitor-mediated controlled ripening of tomato (Solanum lycopersicum L.)
... and 3.68%) than control tomatoes. Similar result was reported for GA on mango (Islam et al., 2013) and for SA on Kiwifruit (Bal and Celik, 2010). As significant decrease in TSS indicates a decrease in food quality, MA ...
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Chemokines and their role in airway hyper-reactivity
... RANTES, MCP-1, MCP-2 and MCP-3 [59–61] augment inflammatory responses within the lung such as leukocyte recruitment and activation, as discussed previ- ously, that further exacerbate ...
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