cell cycle distribution
Differences in Apoptosis and Cell Cycle Distribution between Human Melanoma Cell Lines UACC903 and UACC903(+6), before and after UV Irradiation
... upper right quadrant. The percentages of apoptotic cells were listed in the quadrants. Because floating cells were excluded from analysis, the percentages in the upper right quadrants underestimate the numbers of late ...
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Original Article Silencing of the long non-coding RNA NEAT1 suppresses ovarian cancer cell proliferation, migration and invasion
... In the present study, we evaluated the ex- pression of NEAT1 in ovarian cancer and ovari- an cyst tissues and investigated the relation- ship between NEAT1 expression and clinico- pathological characteristics in ovarian ...
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Synergistic activity of ALK and mTOR inhibitors for the treatment of NPM-ALK positive lymphoma
... the cell cycle level, mTOR inhibition has been described to block cells in G1 phase ...of cell cycle distribution showed a block in G1 phase and a corresponding reduction of the S-phase ...
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Original Article Mefloquine inhibits chondrocytic proliferation by arresting cell cycle in G2/M phase
... carcinoma cell lines and for the treatment of glioblastoma ...and cell cycle in ...and cell cycle distribution, ...caused cell cycle arrests in the G2/M ...the ...
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Schisandrin B inhibits cell growth and induces cellular apoptosis and autophagy in mouse hepatocytes and macrophages: implications for its hepatotoxicity
... on cell growth of AML-12 and RAW ...on cell cycle distribution in both cell lines using flow cytometric ...the cell number in G 1 ...the cell number in G 1 phase, ...
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<p>Down-Regulation of circNRIP1 Promotes the Apoptosis and Inhibits the Migration and Invasion of Gastric Cancer Cells by miR-182/ROCK1 Axis</p>
... cancer cell lines MGC-803 and AGS cells were cultured for study in ...blot. Cell migration, invasion, cell cycle distribution and apoptosis were determined by transwell, fl ow cytometry ...
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Potential mechanism for the effects of dexamethasone on growth of human melanoma cells in vitro
... melanoma cell line in vitro. A retarded cell pro- liferation was observed in M-5A cells with the presence of specific high affinity glucocorticoid steroid ...of cell proliferation in term of reduced ...
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<p>CHFR promotes the migration of human gastric cancer cells by inducing epithelial-to-mesenchymal transition in a HDAC1-dependent manner</p>
... transfection, cell cycle distributions of both cell lines were determined by Pi staining followed by Facs assay (left ...the cell cycle distribution was performed (right ...
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Original Article Glycyrrhizin treatment inhibits proliferation and invasive potential of lung cancer cells
... expression, cell proliferation, invasion potential and cell cycle distribution inhuman lung carcinoma cell line, ...of cell proliferation and caused cell cycle ...
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Original Article Tissue factor (TF) regulates cell viability, proliferation and invasion of human gastric cancer
... Abstract: To investigate the effect of tissue factor (TF) on the biological behaviors of human gastric tumor tissues and cell line. The recombinant pcDNA3.1-antisense TF and pcDNA3.1-sense TF plasmids were ...
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Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells
... on cell cycle distribu- tion in PANC-1 and BxPC-3 cells using flow ...the cell cycle distribution in PANC-1 and BxPC-3 ...the cell cycle distribution in G 1 , S, ...
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Polysaccharide Pst001 Isolated From The Seed Kernel Of Tamarindus Indica Induces Apoptosis In Murine Cancer Cells
... The cell cycle distribution of the cells of each sample was determined using a FACS Calibur instrument (BD Biosciences, San Jose, CA) equipped with Cell Quest Pro ...LT cell ...
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<p>Long Noncoding RNA LINC00265 Targets EGFR and Promotes Deterioration of Colorectal Cancer: A Comprehensive Study Based on Data Mining and in vitro Validation</p>
... impaired cell proliferation and invasion, promoted cell cycle distribution and apoptosis in HT29 ...induces cell proliferation, migration and inhibits CRC cells apoptosis by targeting ...
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Cell Cycle Arrest in Different Cancer Cell Lines “Liver, Breast, and Colon” Induce Apoptosis under the Influence of the Chemical Content of Aeluropus lagopoides Leaves Extracts
... C until required for analysis. Upon analysis, fixed cells were washed with ice-cold PBS and re- suspended in 1 ml of PBS containing 50 µg/ml RNase A and 10 µg/ml propidium iodide (PI). After 20 min incubation at 37 ̊ C, ...
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<p>FANCI Cooperates with IMPDH2 to Promote Lung Adenocarcinoma Tumor Growth via a MEK/ERK/MMPs Pathway</p>
... LUAD cell lines A549 and H1299 cell using three FANCI-targeted ...decreased cell proliferation, as measured using the CCK-8 assay (Figure 3C, ...addition, cell cycle distribution ...
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Review Article Regulation of nasopharyngeal carcinoma cell proliferation by targeting Notch1 with miR-34a
... NPC cell proliferation by targeting Notch1 with miR-34a will be investigated in this ...NPC cell line ...detect cell cycle distribution in order to analyze the changes in cell ...
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The important tumor suppressor role of <em>PER1</em> in regulating the cyclin–CDK–CKI network in SCC15 human oral squamous cell carcinoma cells
... the cell cycle and circadian rhythm. Alterations in cell cycle distribution, cell proliferation, apoptosis, and in vivo tumorigenicity were detected after the PER1 gene was ...
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<p>The synergistic antileukemic effects of eltrombopag and decitabine in myeloid leukemia cells</p>
... Leukemia cell lines were treated with EP, DAC, and EP plus DAC for 72 hrs, and then 5×10 5 cells were collected by ...leukemia cell apoptosis at excitation wavelength (Ex) of =488 nm and emission wavelength ...
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Effects of ionizing radiation on the viability and proliferative behavior of the human glioblastoma T98G cell line
... 14. Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radioresistance by prefer- ential activation of the DNA damage response. Nature. 2006;444:756–60. 15. ...
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Hocke, Sandra (2016): A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancers. Dissertation, LMU München: Medizinische Fakultät
... In response to DNA damage and replication stress, ATR acts as a central checkpoint regulator and mediator of the DNA-repair machinery by homologous recombination (4). ATR- inhibition has recently been demonstrated to ...
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