cell cycle regulation
Emerging Roles for Ciz1 in Cell Cycle Regulation and as a Driver of Tumorigenesis
... to regulation of cellular proliferation, including transcriptional regulators, cell cycle regulators including cyclin E, cyclin A, CDK2, p21 and proteins that are not directly related to DNA ...
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Pocket proteins and cell cycle regulation in inner ear development
... of cell proliferation and highlighting the importance of the activator complexes in cell cycle progression (Wu et ...with cell cycle exit and differentiation (Dimova and Dyson, ...the ...
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Cdks, cyclins and CKIs: roles beyond cell cycle regulation
... Cell cycle control and stem cell self-renewal are two closely related ...of cell cycle regulation characterized by rapidly alternating rounds of S and M phases that are ...
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HE4 overexpression decreases pancreatic cancer Capan-1 cell sensitivity to paclitaxel via cell cycle regulation
... cancer cell line SKOV3 ...of cell proliferation, HE4 knockdown enhanced the drug ...of cell cycle regulators such as PCNA and p21 in both Capan-1 and Suit-2 PDAC cell ...other ...
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miRNA involvement in cell cycle regulation in colorectal cancer cases
... of cell cycle regulation ...the cell cycle that downregulate cell cycle inhibitors, such as Rb, or upregulate cell cycle promoters, such as CDK activators, ...
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Role of Cks85A in cell cycle regulation
... Drosophila cell cycle (Lee and Orr-Weaver, 2003). Cell cycle regulation is not the only role of the Cdk/Cyclin complexes; they have other functions that include regulation of ...
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CtrA Is Nonessential for Cell Cycle Regulation in Rhodobacter sphaeroides
... in cell viability and cell cycle regulation in Sinorhizobium meli- loti [4], Brucella abortus [9] [10], Agrobacterium tumefaciens [4], and Rickettsia prowazekii [4] ...its cell ...
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Yeast ASF1 Protein Is Required for Cell Cycle Regulation of Histone Gene Transcription
... the cell LexA-ASF1 protein showed an even stronger interaction cycle repression of HHT1-HHF1 and HHT2-HHF2 as with GAD-HIR1 in a two-hybrid assay (Table ...under cell cycle control and is ...
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Reovirus-Induced Alterations in Gene Expression Related to Cell Cycle Regulation
... GAC ATC AAC AT-3⬘; reverse primer, 5⬘-TCC CGG CAA AAA CAA ATA AG-3⬘), and -actin (BC004251) (forward primer, 5⬘-GAA ACT ACC TTC AAC TCC ATC-3⬘; reverse primer, 5⬘-CGA GGC CAG GAT GGA GCC GCC-3⬘), yielding product sizes ...
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The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review
... uncontrolled cell proliferation caused by an abnormal cell cycle, and the abnormal expression of cell cycle-related proteins gives tumor cells their invasive, metastatic, ...
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Gene Repression and Cell Cycle Regulation by PU.1 in Acute Myeloid Leukemia
... for cell division; these include genes encoding cell cycle regulators (such as the cyclins indicated above), enzymes involved in nucleotide biosynthesis (such as thymidine kinase), and the main ...
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The effective application of a discrete transition model to explore cell cycle regulation in yeast
... the cell cycle ...this regulation is mediated by either Cln3/Cdk, Cln1/Cdk1 or Clb5/Cdk (Figure ...hand, regulation by either Cln1/Cdk or Clb5/Cdk, showed the expected behavior (Figure 6B, ...
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Original Article Cullin-1 promotes cell proliferation via cell cycle regulation and is a novel in prostate cancer
... A total of 142 pairs of human primary PCa tis- sues and their adjacent NCTs were collected between 2006 and 2009 at Huashan Hospital, Fudan University. These tissue samples were immediately snap-frozen in liquid ...
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Original Article CDC5L contributes to malignant cell proliferation in human osteosarcoma via cell cycle regulation
... for cell division cycle, has been shown to be overexpressed in OS, but its function signifi- cance remains unclear in OS ...OS cell lines Saos-2 and U2OS cells using siRNA trans- ...suppressed ...
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The Role of the Integrated Stress Response Kinase Gcn2 in Cell Cycle Regulation and Tumorigenesis
... to cell survival under amino acid ...for cell growth under nutrient replete conditions but is critical for cell survival during the recovery from amino acid ...promotes cell survival under the ...
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Morphogenesis signaling components influence cell cycle regulation by cyclin dependent kinase
... These results supported the Ras2-activated PKA pathway via Flo8 to be an important regulator of Cdc28. Previous genetic evidence by La Valle and Wittenberg suggested that Swe1 regulation of Cdc28 may be an ...
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Aberrant Cell Cycle Regulation in Cervical Carcinoma
... these cell lines. These cell lines were HPV-positive and carried wild-type p53 ...cancer cell lines, since the HPV viral-transforming proteins E6 or E7 inactivate p53 and pRb tumor suppressor protein ...
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Novel Cell Cycle Regulation in Breast Cancer Treatment Resistance
... epithelial cell tight-tight junctions (Prat et ...for cell- cell junction (Perou, 2010; Perou et ...immune cell infiltration, stem cell features, and features representing ...
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Cell cycle and cell growth regulation by the CUL4-DDB1-ROC1 ubiquitin ligases
... hypothesis is that one of the CUL4-DDB1 ubiquitin ligases targets p53 for ubiquitination, probably through COP1 or one of DWD proteins. COP1 is composed of a RING finger domain and a WD40 repeat, and its catalytic ...
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Glucose Regulation of Saccharomyces cerevisiae Cell Cycle Genes
... ent regulation of BCK2 and CDC28; however, we have shown that these transcripts are upregulated when glucose is added to post-log-phase cells ...of cell cycle reg- ulatory ...
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