Cell growth and invasion
Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells
... of cell growth, invasion, induction of apoptosis, and cell cycle ...assay, invasion assay, RT-PCR, Western blotting, and transfection to explore the functions and molecular insights of ...
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<p>Long noncoding RNA LINC00511 promotes cell growth and invasion in triple-negative breast cancer by interacting with Snail</p>
... MDA-MB-231 cell growth and ...decreased cell viability compared to that of the ...decreased cell invasion ability compared to that in the ...
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<p>Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p</p>
... and cell lines, 18,26,27 and this low expression could contribute to cell proliferation, colony for- mation, cell cycle entrance, migration and invasion of PANC-1 and AsPC-1 cells with ...
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MiR-29c inhibits cell growth, invasion, and migration of pancreatic cancer by targeting <em>ITGB1</em>
... PC cell lines: BxPC-3 and PANC-1. MTT assays and cell-cycle analysis using flow cytometry demonstrated that miR-29c inhibited cell proliferation, at least partially, by inducing cell-cycle ...
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XB130 is overexpressed in prostate cancer and involved in cell growth and invasion
... XB130 in the growth, and survival of certain malignancies. Thus, we examined if XB130 also affect development of prostate cancer which could provide evidence for it being a candidate molecular target of novel ...
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MicroRNA-365 suppresses cell growth and invasion in esophageal squamous cell carcinoma by modulating phosphoserine aminotransferase 1
... cancer cell lines were procured from Cell Collection Center, Shanghai (Chinese Academy of ...ESCC cell lines (EC109, EC1, and EC9706), HEEC, and HEK293T cells for transfection were used in the ...
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CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p
... Results: CircZNF609 was markedly over-expressed in breast cancer tissues and cell lines, and high circZNF609 expression was closely associated with poor outcome. Silencing of circZNF609 inhibited the malignant ...
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Original Article miR-34c-3p inhibits cell proliferation, migration and invasion of hepatocellular carcinoma by targeting MARCKS
... HCC cell growth and invasion are due to MARCKS, we examined the effects of knockdown of MARCKS on the cell proliferation, migration and invasion in HepG2 ...and invasion in HepG2 ...
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Transmembrane-4 L-six family member-1 (TM4SF1) promotes non-small cell lung cancer proliferation, invasion and chemo-resistance through regulating the DDR1/Akt/ERK-mTOR axis
... regulates cell motility and proliferation ...for cell growth in liver and lung cancer [6, 7], motility in lung cancer [7], invasion in pancreatic cancer [8], and metastasis of breast cancer to ...
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<p>The tumor suppressive roles of ARHGAP25 in lung cancer cells</p>
... increased cell growth, migration and invasion can be abrogated by β -catenin inhibitor, XAV939 (Figure 6A and ...inhibit cell proliferation and metastasis by regulating the Wnt/ β - catenin ...
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WISP2 exhibits its potential antitumor activity via targeting ERK and E-cadherin pathways in esophageal cancer cells
... inhibited cell growth and induced cell apoptosis, slowed cell migration and invasion in ESCC cells whereas downregulation of WISP2 has opposed ef- ...
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Hsa-miR-329 exerts tumor suppressor function through down- regulation of MET in non-small cell lung cancer
... non-small cell lung cancer (NSCLC) cell ...cancer cell lines substantially repressed cell growth as evidenced by cell viability assay, colony formation assay and BrdU staining, ...
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Original Article Knockdown of WWP1 inhibits growth and invasion, but induces apoptosis of osteosarcoma cells
... blocked cell growth and cell invasion, and caused G1-phase arrest and cell apoptosis in osteosarcoma cells (MG63 and ...and invasion related factor (MMP2, MMP9, β-catenin and ...
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Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells
... in cell proliferation, we transfected NPC cells with an miR-7 inhibitor and incu- bated them for 72 h prior to measuring cellular proliferation using an MTT ...promoted cell proliferation in both CNE1 and ...
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CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E cadherin
... glioma, cell pro- liferation is suppressed in CHIP silencing U251 and U87 glioma cells, while is promoted in CHIP-overexpressing cells ...supports cell growth of thyroid cancer cells through ...
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The lncRNA DLX6-AS1 promoted cell proliferation, invasion, migration and epithelial-to-mesenchymal transition in bladder cancer via modulating Wnt/β-catenin signaling pathway
... bladder cell lines, and high expression of DLX6-AS1 was correlated with advance TNM stage, lymphatic node metastasis and distant ...cancer cell growth, proliferation, invasion, migration and ...
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ZMYND10, an epigenetically regulated tumor suppressor, exerts tumor-suppressive functions via miR145-5p/NEDD9 axis in breast cancer
... ZMYND10 obviously repressed luciferase reporter activity of NEDD9 (Fig. 6b). By immunofluorescence detected with laser scanning confocal microscopy, reduced NEDD9 expression was seen in ZMYND10-expressing cells than in ...
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Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action
... An exceptionally difficult problem in cancer treatment is multi-drug resistance, i.e., when cancer cells lose their sensitivity to multiple structurally different chemothera- peutics. This is one of the main problems in ...
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Knockdown of long noncoding RNA 00152 (LINC00152) inhibits human retinoblastoma progression
... scramble negative control (NC) shRNA was designed and synthesized by Ribobio (Guangzhou, People’s Republic of China). The shRNAs were inserted into the pGenesil-1 vector (Ribobio) and were used to transform competent ...
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<p>Suppressing growth and invasion of human hepatocellular carcinoma cells by celecoxib through inhibition of cyclooxygenase-2</p>
... more invasion and metastasis in ...uences growth, angiogenesis, invasion, and ...liver cell line L02 and highest in high-invasive HCC cell line ...
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