Cell growth and migration
MiR-29c inhibits cell growth, invasion, and migration of pancreatic cancer by targeting <em>ITGB1</em>
... PC cell lines: BxPC-3 and PANC-1. MTT assays and cell-cycle analysis using flow cytometry demonstrated that miR-29c inhibited cell proliferation, at least partially, by inducing cell-cycle ...
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<p>Blocking circ_0013912 Suppressed Cell Growth, Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells in vitro and in vivo Partially Through Sponging miR-7-5p</p>
... on cell growth, migration and invasion in PDAC cells in ...that cell viability of PANC-1 and AsPC-1 cells were inhibited due to si-circ-1 transfection (Figure 3A), and colony formation assay ...
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CircZNF609 promotes breast cancer cell growth, migration, and invasion by elevating p70S6K1 via sponging miR-145-5p
... Results: CircZNF609 was markedly over-expressed in breast cancer tissues and cell lines, and high circZNF609 expression was closely associated with poor outcome. Silencing of circZNF609 inhibited the malignant ...
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Original Article miR-196 acts as a tumor suppressor in osteosarcoma by targeting HOXA9
... induced cell prolifer- ation and migration inhibition ...on cell prolifera- tion and migration by compar- ing the rates of cell growth and migration in miR-196 inhibitor ...
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miR-23b-3p and miR-130a-5p affect cell growth, migration and invasion by targeting CB1R via the Wnt/β-catenin signaling pathway in gastric carcinoma
... cannabinoids may represent a novel GC therapy and that the WIN 55,212–2 agonist inhibits the proliferation of human GC cells in a dose-dependent manner; however, this effect may be partially mediated by CB1R. In the ...
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<p>Cell Differentiation Agent-2 (CDA-2) Inhibits the Growth and Migration of Saos-2 Cells via miR-124/MAPK1</p>
... osteosarcoma cell growth ...to cell cycle arrest in G1 phase and decreased cyclin D1 ...of growth sup- pression and invasion are two important hallmarks of ...osteosarcoma cell ...
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Emerging role of the peroxisome proliferator-activated receptor-gamma in hepatocellular carcinoma
... chemotherapeutic drugs for local delivery via transcatheter arterial chemoembolization method may provide an alterna- tive approach for HCC treatment. On the other hand, in view of the recent finding that honokiol has ...
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RASSF8 regulates progression of cutaneous melanoma through nuclear factor-κb
... melanoma cell line with low RASSF8 expression, was transfected with RASSF8 expression plasmid to overexpress RASSF8 and high RASSF8 expression cell clones, Wm266-4 RASSF8, were ...expression cell ...
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<p>The tumor suppressive roles of ARHGAP25 in lung cancer cells</p>
... increased cell growth, migration and invasion can be abrogated by β -catenin inhibitor, XAV939 (Figure 6A and ...inhibit cell proliferation and metastasis by regulating the Wnt/ β - catenin ...
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Curcumin exerts its antitumor activity through regulation of miR-7/Skp2/p21 in nasopharyngeal carcinoma cells
... inhibited cell growth, induced apoptosis, retarded cell migration and invasion, and triggered cell cycle arrest in the human nasopharyngeal carcinoma cell lines CNE1 and ...
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Original Article Hsa_circ_0057481 promotes laryngeal cancer proliferation and migration by modulating the miR-200c/ZEB1 axis
... suppressed cell growth, cell cycle progression, invasive and migration potential, and promoted cell apopto- sis in laryngeal cancer HEP-2 and TU212 ...
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Cell migration, intercalation and growth regulate mammalian cochlear extension
... of cell number within a section of the epithelium extending along 100 µm of the axis of extension [base-to-apex (B-A)] indicates a significant decrease of ∼ 42% between E14 and E16 ...in cell volume on ...
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Curcumin suppresses cell growth and invasion and induces apoptosis by down-regulation of Skp2 pathway in glioma cells
... of cell growth, invasion, induction of apoptosis, and cell cycle ...inhibited cell growth, suppressed cell migration and invasion, induced apoptosis and cell cycle ...
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CHIP functions as an oncogene by promoting colorectal cancer metastasis via activation of MAPK and AKT signaling and suppression of E cadherin
... glioma, cell pro- liferation is suppressed in CHIP silencing U251 and U87 glioma cells, while is promoted in CHIP-overexpressing cells ...supports cell growth of thyroid cancer cells through ...
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Original Article Down-regulation of cancer/testis antigen OY-TES-1 attenuates malignant behaviors of hepatocellular carcinoma cells in vitro
... HCC cell lines (HepG2 and BEL-7404) to verify this assumption and evaluate its potential as therapeutic targets for ...decreased cell growth, induced the G 0 /G 1 arrest and apoptosis, and pre- ...
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Hsa-miR-329 exerts tumor suppressor function through down- regulation of MET in non-small cell lung cancer
... NSCLC cell lines A549, H1299, SPC-A-1, SK-MES-1, 95-D and NCI-H520 in comparison to normal lung cell line ...cancer cell lines (A549 and ...NSCLC cell (A549 and H1299) proliferation, ...
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Suppression of Spry4 enhances cancer stem cell properties of human MDA-MB-231 breast carcinoma cells
... (NT) cell lines were obtained by puromy- cin ...1a). Growth curve analyses showed that suppression of Spry4 led to an increase in cell number over a ten-day cell growth period ...1b). ...
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The Role of MicroRNAs in Myeloproliferative Neoplasia
... to cell cycle stimulation, apoptosis inhibition, preservation of self-renewal of stem cells and differentiation regulation of tissue stem ...reduced cell proliferation as well as increased apoptosis in CD34 ...
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Hematopoietic Stem Cell-derived Adipocytes Promote Tumor Growth and Cancer Cell Migration
... insulin-like growth factor-1 (IGF-1), monocyte chemotactic protein-1 (MCP-1), and vascular endothelial growth factor (VEGF) (Figure 1D, Supplementary Figure ...hepatocyte growth factor (HGF) was ...
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Hepatocyte growth factor is the most potent endogenous stimulant of rabbit gastric epithelial cell proliferation and migration in primary culture
... restitution model. HGF was the most effective agent for facilitating gastric epithelial restitution among those tested. A binding assay revealed specific binding of HGF to its receptor on gastric epithelial cells. ...
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