cell penetrating peptides
Chemical-functional diversity in cell-penetrating peptides
... Abstract Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane ...these peptides suffer from inconsistencies in used techniques and other experimental ...
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In silico approaches for designing highly effective cell penetrating peptides
... Conclusion: The present study demonstrates that features like amino acid composition, binary profile of patterns and motifs, can be used to train an SVM classifier that can predict cell penetrating ...
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Cell-Penetrating Peptides—Mechanisms of Cellular Uptake and Generation of Delivery Systems
... derived peptides, can translocate across biological membranes, cell-penetrating peptides (CPPs) have been considered one of the most promising tools to improve non-invasive cellular delivery ...
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Cell-penetrating peptides as a promising tool for delivery of various molecules into the cells
... of cell-penetrating peptides have made this group of compounds one of the most widely studied over the past 25 ...The penetrating properties of CPPs increase the efficiency of the delivery of ...
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Cell-penetrating peptides: 20years later, where do we stand?
... of peptides able to cross cellular membranes launched a novel field in molecular delivery based on these non-invasive vectors, most commonly called cell-penetrating peptides (CPPs) or protein ...
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Modeling the endosomal escape of cell-penetrating peptides using a transmembrane pH gradient
... Cell-penetrating peptides (CPPs) can internalize into cells with covalently or non-covalently bound biologi- cally active cargo molecules, which by themselves are not able to pass the cell ...
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Metabolic Cleavage and Translocation Efficiency of Selected Cell Penetrating Peptides: A Comparative Study with Epithelial Cell Cultures
... WORDS: cell penetrating peptides; cellular translocation; epithelial cell cultures; metabolic cleavage; metabolism ...so-called cell penetrating peptides (CPPs) has turned ...
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A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery.
... 1,2 Cell penetrating peptides (CPPs) offer great potential to deliver therapeutic molecules to previously inaccessible intracellular ...of peptides delivering a wide range of cargos into the ...
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A platform for discovery of functional cell-penetrating peptides for efficient multi-cargo intracellular delivery
... Cell penetrating peptides (CPPs) offer great potential to deliver therapeutic molecules to previously inaccessible intracellular ...of peptides delivering a wide range of cargos into the ...
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Click to enter: activation of oligo-arginine cell-penetrating peptides by bioorthogonal tetrazine ligations
... Cell-penetrating peptides are able to transport a wide variety of cargo across cell ...octa-arginine cell-penetrating peptide (CPP) that can be activated by means of ...
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To what extent do cell-penetrating peptides selectively cross the blood-brain barrier?
... 1. CELL-PENETRATING PEPTIDES The ability of peptides to traverse the phospholipid bilayer of cell membranes was discovered more than 20 years ago, when it was demonstrated that the ...
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Precise quantification of cellular uptake of cell-penetrating peptides using fluorescence-activated cell sorting and fluorescence correlation spectroscopy
... 2016 Cell-penetrating peptides (CPPs) have emerged as a potentially powerful tool for drug delivery due to their ability to efficiently transport a whole host of biologically active cargoes into ...
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Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell-penetrating peptides
... vivo cell modulation/tracking are translated for regenerative medicine ...of cell penetrating peptides in order to achieve exceptional intracellular ...utilises peptides which interact ...
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Highly efficient delivery of functional cargoes by the synergistic effect of GAG binding motifs and cell penetrating peptides
... vivo cell modulation/tracking are translated for regenerative medicine ...of cell penetrating peptides in order to achieve exceptional intracellular ...utilises peptides which interact ...
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Conjugation of cell-penetrating peptides with poly(lactic-co-glycolic acid)-polyethylene glycol nanoparticles improves ocular drug delivery
... Furthermore, cell-penetrating peptides (CPPs) can be conjugated with NPs to enhance the cellular and nuclear uptake of the cargo ...including peptides, proteins, viral particles, liposomes, ...
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Fusion of cell-penetrating peptides to thermally responsive biopolymer improves tumor accumulation of p21 peptide in a mouse model of pancreatic cancer
... Dovepress Cell-penetrating peptides increase uptake in hyperthermic tumors Because of the thermal properties of ELP, mild hyper- thermia triggers ELP to undergo a phase transition to form aggregates ...
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Tünnemann, Gisela (2009): Toxicity, uptake and applications of intracellular delivery by cell penetrating peptides. Dissertation, LMU München: Fakultät für Biologie
... Abstract: Cell penetrating peptides (CPPs) are useful tools to deliver low-molecular-weight cargoes into cells; however, their mode of uptake is still ...arginine-rich peptides, but a ...
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Taming cell-penetrating peptides : a steering wheel for delivery vehicles
... Delivery of proteins to cells can be achieved by means of functionalization of the protein of interest with a CPP. However, conventional functionalization methodologies involve either expression of the protein as ...
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The use of cell penetrating peptides to treat inflammatory responses in uterine cells
... of peptides across the full concentration range and time course, statistical analysis of quantitative data suggested that addition of rhodamine-R8 led to the largest increases in fluorescence within myometrial ...
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From cell penetrating peptides to peptoids and polyamines as novel. artificial molecular transporters
... In many tumors anti-apoptotic proto-oncogenes are overexpressed or mutated to a constitutively active form, so that apoptosis is impaired. These cells become resistant to chemotherapy and apoptosis triggered by the death ...
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