cell polarity
The cadherin Fat2 is required for planar cell polarity in the Drosophila ovary
... planar cell polarity proteins Frizzled, Dishevelled, Diego, Prickle and Strabismus/Van Gogh are required for the planar-polarized orientation of hairs (Adler et ...planar cell polarity ...
10
Is a Persistent Global Bias Necessary for the Establishment of Planar Cell Polarity?
... Planar cell polarity (PCP)–the coordinated polarisation of a whole field of cells within the plane of a tissue–relies on the interaction of three modules: a global module that couples individual cellular ...
12
Cell polarity and morphogenesis : functions and mechanisms of cell divisions in vertebrate gastrulation
... Wnt/planar cell polarity (Wnt/PCP) ...oriented cell division is mediated by spindle ...that cell polarization underlies the morphogenetic machinery that shapes the head-to-tail ...the ...
124
Roles of planar cell polarity pathways in the development of neutral tube defects
... Three Fmi gene orthologs in human and rodents are named celser1 - celser3 respectively. Fmi genes encode proteins of the cadherin superfamily which are seven transmembrane proteins with nine cadherin repeats in the ...
10
Acquisition of cell polarity during cell cycle and oral replacement in Tetrahymena
... of cell polarity in metazoan neural cells (Doble and Woodgett, 2003) and non-neural cells (Etienne-Manneville and Hall, ...of cell polarity involves the cascade of activities of specific ...
11
Stomatal development: a plant's perspective on cell polarity, cell fate transitions and intercellular communication
... Asymmetric cell division and division polarity of stomata in ...oriented polarity, respectively. Polarity is seen in cell sizes and division orientations, but also in the localization ...
10
Regulation of long range planar cell polarity by Fat Dachsous signaling
... planar cell polarity ...altered polarity (Casal et ...of polarity in wild-type tissue, called domineering non-autonomy (Krasnow et ...many cell lengths, indicating that the Ft-Ds ...
13
Cell polarity: models and mechanisms from yeast, worms and flies
... 1. Cell polarity in budding yeast, the worm zygote and the fly follicular ...of polarity determinants (A,C,E) and the domain structure and interactions between determinants (B,D,F) are shown for ...
9
Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression
... mother cell (Doe, 2008; Knoblich, 2008), which typically divides once to form two postmitotic ...neuroblasts, cell polarity is disturbed such that Miranda and Numb basal proteins become distributed ...
8
Coupling of apical basal polarity and planar cell polarity to interpret the Wnt signaling gradient in feather development
... orient cell growth is crucial in tissue ...planar cell polarity gene Prickle1 is involved, as knockdown of its expression resulted in no cell shape change and no barb ...apical-basal ...
8
Tissue/planar cell polarity in vertebrates: new insights and new questions
... affects cell polarity within an epithelial plane and involves one or more of the core PCP genes (as defined by the PCP phenotype of the Drosophila ...in cell or tissue patterning but which do not ...
12
Planar cell polarity in moving cells: think globally, act locally
... planar cell polarity (PCP) pathway, the fundamental function of which is the communication of polarity information between adjacent cells in the plane of a tissue, with outcomes are that are ...
14
From top to bottom: Cell polarity in Hedgehog and Wnt trafficking
... increased in the last 10 years, coinciding with the great ad- vance in imaging techniques. Cytonemes are actin-based filopodia functionally specialized in signalling [4, 89]. For both Wnt and Hh, we and others have ...
11
Novel Regulators of Planar Cell Polarity: A Genetic Analysis in Drosophila
... ABSTRACT Planar cell polarity (PCP) is a common feature of many epithelia and epithelial organs. Although progress has been made in the dissection of molecular mechanisms regulating PCP, many questions ...
23
Epithelial Cell Polarity Determinant CRB3 in Cancer Development
... epithelial cell polarity by repressing the transcription of CRB3 and abolishing the localization of Par and CRB complexes at cell-cell junctions in MDCK cells ...epithelial cell lines ...
7
SEGGA: a toolset for rapid automated analysis of epithelial cell polarity and dynamics
... planar polarity at earlier stages in fixed embryos using phalloidin staining (Blankenship et ...planar polarity in movies might be due to the low signal-to-noise ratio of the GFP markers used to visualize ...
10
An intracellular partitioning based framework for tissue cell polarity in plants and animals
... cases, cell polarity is coordinated across a large domain of tissue, such as a wing or ...this polarity is related to the overall morphology of the structure, such as its proximodistal ...influence ...
14
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
... Fig. 1. Dishevelled mediates at least three signaling cascades. (A) The canonical WNT pathway. WNT signals are received by a Frizzled (FZ) receptor and a LRP co-receptor. The signal is transduced through Dishevelled and ...
16
Gpr125 modulates Dishevelled distribution and planar cell polarity signaling
... Wnt/planar cell polarity (PCP) signaling orchestrates polarized cell behaviors underlying convergence and extension (C&E) movements to narrow embryonic tissues mediolaterally and lengthen them ...
12
Cofilin and Vangl2 cooperate in the initiation of planar cell polarity in the mouse embryo
... The stronger phenotypes of the Vangl1 Vangl2 double mutants and the Dvl1/Dvl2/Dvl3 compound mutants compared with single PCP mutants provide a tool to identify other proteins required for planar cell ...
10