Cell Transformation
Knockout of Epstein Barr Virus BPLF1 Retards B Cell Transformation and Lymphoma Formation in Humanized Mice
... in cell culture by infection with ...Additionally, transformation of B-cells has been shown to be dependent on expres- sion of the latency genes for LMP1, EBNA2, and EBNA3A and EBNA3C (59, ...
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Essential Roles of mTOR/Akt Pathway in Aurora-A Cell Transformation
... Roles of Akt in cell transformation have been well illustrated. Recent studies have demonstrated that TORC2 complex that contains mTOR, mLST8, Rictor, mSin1 and Protor phosphorylates Akt at Ser473 (16-18). ...
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Mammary epithelial cell transformation: insights from cell culture and mouse models
... in cell proliferation at this stage is dependent on the pRb/p16 pathway [24,35], because the human papillomavirus (HPV) oncogene E7, which binds and inactivates pRb, can over- come the M0/selection stage ...as ...
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Regulation of epithelial cell transformation and survival by Raf activation
... strong cell-cell adhesion and cell polarity, is lost and a mesenchymal phenotype is acquired, characterised by reduced cell-cell contacts and increased motility (Schoenenberger et ...
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Envelope-Induced Cell Transformation by Ovine Betaretroviruses
... induce transformation of rodent fibroblasts in ...of cell transformation, and in ENTV Env-trans- formed cells it is possible to detect phosphorylated ...betaretrovirus-induced cell transfor- ...
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Synergistic method for host cell transformation
... This invention addresses the problem of inserting foreign or nonative DNA into a cell and, most particularly, into a plant cell. The solution to this problem of DNA transfer set forth in this invention is ...
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Role of oligomerization of the S13 Env-Sea oncoprotein in cell transformation.
... HAYMAN* Department of Microbiology, State University of New York at Stony Brook, Stony Brook New York 11794-5222 Received 1 June 1993/Accepted 24 November 1993 The env-sea oncogene is a [r] ...
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Basal Cell Proliferation Induced by Chlormadinone Acetate Suggests Stem Cell Transformation of Prostatic Cells
... glandular cells. Specimens from 6 months dutasteride use showed marked atrophic glandular structures, though other specimens did not. Among the stem cell markers, only CD44 showed different staining results ...
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Mesenchymal stem cell transformation and sarcoma genesis
... ated cell type is a process with a lot of different signaling pathways and differentiation stages involved (Figure ...targeted cell and also the targeted molecular ...muscle cell progenitors ...
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Epstein-Barr Virus Latent Membrane Protein 2A Mediates Transformation through Constitutive Activation of the Ras/PI3-K/Akt Pathway
... Anchorage-independent cell growth of HaCaT and HSC-39 cells expressing ...keratinocyte cell line in part through the activation of the PI3-K/Akt pathway ...LMP2A-mediated cell transformation, ...
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Marek's disease virus (MDV) ICP4, pp38, and meq genes are involved in the maintenance of transformation of MDCC-MSB1 MDV-transformed lymphoblastoid cells.
... T-cell transformation by MDV are unknown, but several experimental approaches have been taken to identify viral genes that contribute to the initiation and/or maintenance of ...
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The adenovirus E1A 12S product displays functional redundancy in activating the human proliferating cell nuclear antigen promoter.
... Sequences in ElA proteins of human adenovirus 5 required for cell transformation, repression of a transcriptional enhancer, and induction of proliferating cell nuclear antigen.. Inductio[r] ...
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p85α promotes nucleolin transcription and subsequently enhances EGFR mRNA stability and EGF-induced malignant cellular transformation
... of cell transformation, we first utilized EGF as a tumor promoter to establish an EGF-induced cell malignant transformation experimental system [27] and consequently evaluated EGF-induced ...
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Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma
... for cell cycle progression in several cell sys- tems and also for cell transformation induced by a vari- ety of oncogenes, including Src, Ras and Raf ...synthesis, cell cycle control ...
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An Analysis of Mek1 Signaling in Cell Proliferation and Transformation
... morphological transformation within 24 h ...elicit cell transformation events is no greater than 12–18 ...weak cell growth response compared with ...
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Whole-cell fungal transformation of precursors into dyes
... the transformation of 1 mM benzene and naphthalene derivatives in liquid cultures yielding stable and non-toxic products with good dyeing ...48-hour transformation of the selected precursors, and the most ...
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Does the immune reaction cause malignant transformation by disrupting cell-to-cell or cell-to-matrix communications?
... possible [21]. Nevi are also more numerous in patients suffering from AIDS which suggests that it is indeed immunosuppression per se that is responsible for the increase [21]. I argue that it is probably not lack of ...
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Mechanism of Cell Entry and Transformation by Enzootic Nasal Tumor Virus
... vitro cell culture system for growing the ...most cell types tested ...ovine cell lines, it replicates poorly and little virus is produced ...JSRV cell surface receptor ...same cell ...
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Phenotypic transformation of the host cell enhances polyoma pseudovirion formation.
... Progeny resulting from a polyoma virus infection of a variety of transformed mouse cell types consisted of predominantly pseudovirus, whereas mouse 3T3 cells produced mainly polyoma viru[r] ...
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EFFICIENT REGENERATION AND AGROBACTERIUM-MEDIATED TRANSFORMATION PROTOCOL FOR RECALCITRANT INDICA RICE (ORYZA SATIVA L.).
... The crosstalk between the transport and metabolism of carbohydrate and phytohormone signaling during plant development has always been a research topic that has yet to be fully understood (Eveland and Jackson, 2012). ...
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