Cerebellar Degeneration
Cerebellar degeneration in harlequin mice is associated with inflammation unaltered by low-dose phenobarbital treatment
... of cerebellar degeneration leaner, lurcher, reeler, staggerer, and weaver display ataxia or disturbances in gait ...of cerebellar degeneration all display loss of Purkinje and granule cells ...
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Alcohol related cerebellar degeneration: not all down to toxicity?
... alcohol-related cerebellar degeneration preferentially affects the cerebellar vermis [2 – ...paraneoplastic cerebellar degeneration and primary autoimmune cerebellar ataxia ...
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Alcohol-related cerebellar degeneration: not all down to toxicity?
... in cerebellar degeneration in patients with alcohol ...perpetuate cerebellar degeneration even when the patient abstains from alcohol ...
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Essential tremor: the most common form of cerebellar degeneration?
... Despite its extraordinarily high prevalence, the patho- mechanisms of ET have been elusive [47, 127–129]. Even the localization of the site of primary pathology within the brain has been a major challenge. In part, this ...
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Paraneoplastic cerebellar degeneration.I.A clinical analysis of 55 anti‐Yo antibody‐positive patients
... Article abstract-We reviewed the clinical findings in 55 patients with cerebellar degeneration associated with the anti-Yo antibody (an anti-Purkinje cell antibody identified[r] ...
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Effects of transcranial direct current stimulation on grip force control in patients with cerebellar degeneration
... pure cerebellar degeneration (6 females; mean age ± SD of ...of cerebellar symptoms in cerebellar participants were assessed by two experienced neurologists (DT & MK) based on the ...
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IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration
... Paraneoplastic cerebellar degeneration (PCD) is characterized by the selective loss of Purkinje neurons in the cerebellum ...frequently cerebellar degeneration- related antigen (CDR2/CDR2L), ...
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The combined effect of cranial-nerve non-invasive neuromodulation with high-intensity physiotherapy on gait and balance in a patient with cerebellar degeneration: a case report
... Background: Cranial-nerve non-invasive neuromodulation (CN-NINM) using the portable neuromodulation stimulator (PoNS ™ ) device has been proposed as a novel adjuvant intervention to improve efficacy of gait and balance. ...
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A SEX-LINKED RECESSIVE DISORDER WITH RETARDATION OF GROWTH, PECULIAR HAIR, AND FOCAL CEREBRAL AND CEREBELLAR DEGENERATION
... central white matter was degenerated, rare fled, and showed marked proliferation and hypertrophv of the astrocytes. Tile white matter just i)eneath the cortex in tilese areas showed cyst[r] ...
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Gene Discovery in Hereditary Cerebellar Cortical Degeneration of Scottish Terriers.
... 88 these dissertation studies. Despite our many interesting outcomes regarding this poorly described disease in this breed, study limitations must be acknowledged, including the following: 1) Difficulty in diagnosing ...
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Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death
... available cerebellar degeneration mutant mice, Lurcher is a fairly close phenocopy of pcd, as Lurcher mice display post-developmental degeneration of Purkinje cell neurons over the course of four ...
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Volumetric evaluation of hemicerebellar changes in migraine patients without aura
... by cerebellar infarction [5]. Cerebellar vo- lume changes due to unilateral cerebral lesions which were associated with atrophy of the contralateral cerebellar hemisphere are not rare ...
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‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 3: Anti-Yo/CDR2, anti-Nb/AP3B2, PCA-2, anti-Tr/DNER, other antibodies, diagnostic pitfalls, summary and outlook
... idiopathic cerebellar ataxia, since these autoantibodies may indicate cancer, determine treatment and predict ...autoimmune cerebellar ataxia (ACA); part 2 covers anti-protein kinase C gamma-, ...
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CT findings in spinocerebellar degeneration
... Alcoholic cerebellar degeneration showed a specific pattern of cerebellar atrophy most prominent in the superior vermis, together with a slight increase in the fourth ventricle surface, [r] ...
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Guidelines for treatment of immune-mediated cerebellar ataxias
... paraneoplastic cerebellar degeneration (PCD) amongst paraneoplastic neurological syndromes [1, ...immune-mediated cerebellar ataxias (CAs) was established recently ...associated cerebellar ...
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‘Medusa head ataxia’: the expanding spectrum of Purkinje cell antibodies in autoimmune cerebellar ataxia. Part 1: Anti-mGluR1, anti-Homer-3, anti-Sj/ITPR1 and anti-CARP VIII
... autoimmune cerebellar ataxia; AChR: acetylcholine receptor; ADEM: acute disseminated encephalomyelitis; AF: Alexa Fluor®; AGNA: anti-glial cell nuclear antibodies; AMPA: α -amino-3-hydroxy-5-methyl- ...
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The Shrunken, Bright Cerebellum: A Characteristic MRI Finding in Congenital Disorders of Glycosylation Type 1a
... of cerebellar volume loss was very mild, the cerebellar vermis had a near-normal appearance with only mild folial volume reduction at presentation, which progressed on ...of cerebellar cor- tical ...
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Mechanisms of human cerebellar dysmetria: experimental evidence and current conceptual bases
... that cerebellar dysmetria mainly results from a deficit in the predictive feedforward control (Figure ...the cerebellar circuitry, and the pertinent interaction of mossy and climbing fibres ...[86]. ...
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Diffusion Tractography Biomarkers of Pediatric Cerebellar Hypoplasia/Atrophy: Preliminary Results Using Constrained Spherical Deconvolution
... of cerebellar WM tracts is preserved (eg, normal axonal packing, diameter, and myelination) and that a malformed cere- bellum does not cause a secondary alteration of the connecting WM tracts (at least detectable ...
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MR Imaging of Gray Matter Involvement in Multiple Sclerosis: Implications for Understanding Disease Pathophysiology and Monitoring Treatment Efficacy
... The evaluation of the regional patterns of GM involvement has undoubtedly improved the correlation with disease clini- cal manifestations. In patients with CIS, voxel-wise correla- tions with clinical measures showed ...
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