cerebral ischaemia
Tau pathology and neurochemical changes associated with memory dysfunction in an optimised murine model of global cerebral ischaemia - A potential model for vascular dementia?
... Cerebral ischaemia, which results from stroke, cardiac arrest and cardiac surgery, is one of the most common causes of death and disability worldwide (Flynn et ...(focal ischaemia) whereas global ...
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A nested mechanistic sub study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH 3 Trial Intracranial Bleeding Mechanistic Sub Study [CRASH 3 IBMS])
... of cerebral ischaemia, we would expect to see more ischaemic lesions in tranexamic acid-treated patients, particularly in those treated after a more prolonged period following injury ...and cerebral ...
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Pentraxin 3 mediates neurogenesis and angiogenesis after cerebral ischaemia
... angiogenic factor in vitro and in matrigel or alginate bead implants ex vivo [34,35]. In contrast, our data show that PTX3 exerts pro-angiogenic actions on the cerebrovascu- lar endothelium, indicating that PTX3 actions ...
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Studies of experimental cerebral ischaemia using nuclear magnetic resonance and hydrogen clearance.
... cerebral ischaemia. Studies in primates following acute middle cerebral artery occlusion have shown that when CBF drops below 18 ml 100 g'1 min*1 the EEG becomes isoelectric, and evoked potentials ...
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Potential Protective effect of Vitamin C on Cerebral Ischaemia Reperfusion Injury in Rats
... Cerebral Ischaemia/reperfusion injury(I/RI)is a common cause of brain ...against cerebral I/RI, induced in rats and its effect on biomarkers of oxidative and nitrosative stress, and on markers of ...
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Cerebral haemodynamics and the role of nitric oxide production following transient cerebral ischaemia in the developing brain
... of cerebral injury (Williams CE et al ...Delayed cerebral injury is an important feature of perinatal asphyxia in term infants, and has been repeatedly measured with MRS (Azzopardi D and Edwards AD, ...
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Magnetic resonance imaging of diffusion and perfusion: Techniques and applications to cerebral ischaemia
... since cerebral vascular disorders are among the most common causes of death and disease in the Western ...the cerebral circulation results in the death of nerve cells within 5 ...
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Studies of experimental cerebral ischaemia using magnetic resonance imaging and autoradiography
... transient ischaemia or hypoxic ischaemia, DSCI has been used to detect the change in CBV during and after the insult (D'Arceuil et a l ...of ischaemia and reperfusion, and provided additional ...
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Original Article Hemodynamic study about laminar shear stress extenuate cerebral ischaemia-reperfusion injury
... Apoptosis is a dynamic process and can be regulated by a series of genes and proteins [14, 15]. In ischaemic stroke studies, apoptosis usually occurred in the penumbra region. Pr- evious research indicated that at ...
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Plasma viscosity changes during haemodilution therapy of cerebral ischaemia
... F ollo w i n g MCAO, the greatest reductions in tissue oxygen tension were recorded in areas of the b r a i n w here the largest reductions in cerebral b l ood flow occurred. Figure 4 .5.a, d emonstrates a linear ...
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Perfusion and diffusion magnetic resonance imaging studies of cerebral ischaemia
... f cerebral ischaem ia (deficient blood supply to the brain and the consequent im pairm ent in the availability o f oxygen and ...f cerebral and myocardial ...
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Alterations in insterstitial acid-base homeostasis during cerebral ischaemia
... As both elicitation and propagation of SD require activation o f the NMDA receptor ionophore complex (Lauritzen and Hansen, 1992; Sheardown, 1993), probenecid may inhibit SD by reducing NMDA receptor activation. ...
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Comorbid neuropathologies in migraine
... and cerebral ischaemia sharing a common cause Migraine and cerebral ischaemia sharing a common cause include syndromes in which both migraine and stroke are major clinical ...include ...
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Multidetector computed tomography of mesenteric ischaemia
... Abdominal radiographs and ultrasound (US) are of limited value, with poor sensitivity and specificity in diagnosing mesenteric ischaemia, but may be performed in patients with nonspecific abdominal pain [2, 6]. ...
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Mild episodes of tourniquet-induced forearm ischaemia-reperfusion injury results in leukocyte activation and changes in inflammatory and coagulation markers
... of ischaemia and reperfusion in normal humans, monocytes and neutrophils are rapidly activated, accumu- late within the vasculature and produce potent reactive oxygen ...
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Clinical review: Splanchnic ischaemia
... Tissue hypoxia in patients during CPB may be induced by low blood pressure or by insufficient tissue perfusion due to limited pump flow, or both. The relative importance of flow versus pressure in splanchnic perfusion ...
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Apoptotic cell administration is detrimental in murine renal ischaemia reperfusion injury
... an initial experiment early ACs were administered prior to 25 mins of ischaemia but no preservation of renal function was observed (Figure 2A). The resulting level of functional injury was high with markedly ...
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Gaseous mediators: an updated review on the effects of helium beyond blowing up balloons
... adenosine triphosphate-regulated potassium channel (mitoKATP), (2) generation of a small reactive oxygen species (ROS) burst and (3) maintenance of the mPTP. It is very likely that these mechanisms are also involved in ...
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A Case Control Study Of Retinal Vessel Diameter In Patients Of Retinal Ischaemia And Patients Without Retinal Ischaemia
... of ischaemia and if caught in their prime, may not cause severe loss of ...retinal ischaemia were males and 35 % were females, the reason of which are manifold including greater susceptibility of male for ...
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Acute mesenteric ischaemia: a pictorial review
... mesenteric ischaemia (AMI) is an uncommon cause of acute hospital admission with high mortality rates (50–90%) that requires early diagnosis and ...bowel ischaemia are not ...
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