Chagas disease
The history of Chagas disease
... from Chagas disease later in his life. However, Chagas disease is a most unlikely diagnosis for Darwin’s chronic illness as the symptoms abated as he aged, as he did not seem to have any of ...
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The neuropeptide CCHamide2 regulates diuresis in the Chagas disease vector Rhodnius prolixus
... of Chagas disease, is ingested by triatomines with the blood of an infected ...of Chagas disease, it is still occurring in endemic regions of Latin ...
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Idiotypic sensitization in utero of children born to mothers with schistosomiasis or Chagas' disease
... Cord blood mononuclear cells CBMC of neonates born of mothers with Chagas' disease or schistosomiasis exhibited strong proliferative responses against idiotypes expressed on antibodies w[r] ...
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Evaluation of Recombinant Antigens for Serodiagnosis of Chagas’ Disease in South and Central America
... To overcome this problem, in the present study six T. cruzi recombinant proteins in fusion with glutathione S-transferase (GST) were expressed in bacteria and used to develop an enzyme-linked immunosorbent assay (ELISA). ...
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Dominant T and B cell epitopes in an autoantigen linked to Chagas’ disease
... Chagas’ disease affects several million people in Cen- tral and South America and is considered a paradigm of autoimmune ...the disease in their life- time, which include cardiomyopathy, ...
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Intra Domiciliary Transmission of Chagas’ Disease in Rural Areas of Yucatan Mexico
... the disease in Yucatan, there is no accurate data on the dynamics of domiciliary transmission of Chagas disease, however there are previously studies conducted in the Yucatan peninsula which ...
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Antibodies to an Epitope from the Cha Human Autoantigen Are Markers of Chagas' Disease
... Chagas’ disease is a prevalent disease in South America that is thought to have an autoimmune ...of Chagas’ disease, including a therapeutically treated ...for Chagas’ ...
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<p>Advances in nanocarriers as drug delivery systems in Chagas disease</p>
... Abstract: Chagas disease is one of the most important public health problems in Latin America due to its high mortality and morbidity ...this disease since drugs are usually toxic with low ...achieve ...
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Implications of genetic variability of Trypanosoma cruzi for the pathogenesis of Chagas disease
... absence of intramural nerve plexi in the esopha- gus due to T. cruzi infection and leading to loss of peristalsis in the esophageal body and the lack of opening of the lower esophageal sphincter in response to ...
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Translational challenges of animal models in Chagas disease drug development: a review
... Abstract: Chagas disease, or American trypanosomiasis, caused by Trypanosoma cruzi parasite infection is endemic in Latin America and presents an increasing clinical challenge due to migrating ...for ...
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New Treatments for Chagas Disease and the Relationship between Chagasic Patients and Cancers
... Abstract: Chagas disease is an infectious illness with a broad distribution throughout the South American and African continents, importantly influencing human morbidity and mortality and a controversial ...
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Multiple causes of death related to Chagas' disease in Brazil, 1999 to 2007
... Introduction: Chagas’ disease is a major public health problem in Brazil and needs extensive and reliable information to support consistent prevention and control ...to Chagas’ disease ...
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Effects of ghrelin supplementation on the acute phase of Chagas disease in rats
... A complex cellular and humoral immune response is mobilized against T. cruzi infection, performing an import role in the parasite-host relationship [42, 43]. During the acute phase of Chagas disease, the ...
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Regional biogeography of microbiota composition in the Chagas disease vector Rhodnius pallescens
... a Chagas disease vector. Chagas disease, caused by the kinetoplastid protozoan parasite Trypa- nosoma cruzi, is transmitted between a wide range of potential mammalian hosts and humans by ...
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Chagas disease: a report of 17 suspected cases in Japan, 2012–2017
... of Chagas disease in European countries, systemic screen- ing for Chagas disease in asymptomatic Latin American residents is considered a cost-effective public health strategy ...of ...
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Adverse Events After the Use of Benznidazole in Infants and Children With Chagas Disease
... and Chagas Service at the Children’s Hospital “Ricardo Gutier- rez” of Buenos Aires were ...gas disease; T cruzi infection was de- fined as at least 2 reactive serologic tests for patients over 6 months old; ...
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Comprehensive left ventricular mechanics analysis by speckle tracking echocardiography in Chagas disease
... Background: Chagas disease (CD) is a frequent cause of dilated cardiomyopathy (CMP) in developing countries, leading to clinical heart failure and worse ...
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Monocyte glycolysis determines CD8+ T cell functionality in human Chagas disease
... Chagas disease, a complex pathological condition resulting from Trypanosoma cruzi infection, has become one of the most frequent causes of heart failure, cardio-embolic stroke, and sudden death in Latin ...
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Chagas disease: an impediment in achieving the Millennium Development Goals in Latin America
... American trypanosomiasis manifests with acute and chronic (early and late) phases [5,7-9,11]. In some indi- viduals, parasitization of cardiac muscle or brain during acute infection can lead to myocarditis or meningoen- ...
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Increased mortality attributed to Chagas disease: a systematic review and meta analysis
... of disease progression and mortality. By classifying Chagas patients using standard clinical stages used for other heart disease conditions ...way disease progression and mortality can be ...
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