Chemokines and Inflammation
Eosinophil recruitment to the lung in a murine model of allergic inflammation The role of T cells, chemokines, and adhesion receptors
... Since chemokines are important inflammatory mediators involved in the recruitment and acti- vation of leukocytes at sites of inflammation, we tried to corre- late OVA-induced eosinophil, T-lymphocyte, and ...
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Original Article Specific chemokines CCL2 and CCL17 are correlated with hepatic necro-inflammation in chronic hepatitis B patients with normal/mildly elevated alanine aminotransaminase levels
... (52/70) in patients that were correctly eval- uated. This initial study has several limitations. It was conducted at a single center and involved a small study sample, with a small number of subjects being enrolled in ...
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Roles of neutrophils in the regulation of the extent of human inflammation through delivery of IL-1 and clearance of chemokines
... of inflammation were small, a number of volunteers showed a rapid blood neutrophilia, demonstrat- ing a remarkably sensitive ability of the innate immune system to ready the human organism when bacterial infection ...
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CHEMOKINES ARE CRUCIAL
... tients experienced typical symptoms, such as headache, nasal obstruction, and discolored nasal drainage arising from the na- sal passages, that persisted for 12 weeks or longer and showed edema or erythema of the middle ...
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TRPM2 exacerbates central nervous system inflammation in experimental autoimmune encephalomyelitis by increasing production of CXCL2 chemokines
... acute inflammation, but also in chronic inflammatory diseases including MS ( Caielli et ...neutrophil chemokines CXCL1, CXCL5, and neutrophil elastase correlates with clinical and ra- diological measures of ...
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Chemokines and their receptors in ovarian cancer
... chronic inflammation leads to reversible airway obstruction and bronchopulmonary hyper-responsiveness as well as mucous gland hyperplasia and subepithelial ...
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Chemokines and their role in airway hyper-reactivity
... allergic inflammation, have been shown to acti- vate mast cells directly ...airway inflammation, it has been demonstrated that anti-MCP-1 antibodies inhibit AHR to methacholine and attenuate histamine ...
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Emerging roles of chemokines in prostate cancer
... So far, the factors responsible for PCa progression remain elusive. Among the mediators of carcinogen- esis, the significance of chemokines in PCa progression has increased. In multicellular organisms, the ...
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p53, chemokines, and squamous cell carcinoma
... between inflammation and cancer has been well documented, from the influence of chron- ic inflammatory agents on neoplastic cell proliferation in founding a tumor to later stages of tumor progression associ- ated ...
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The role of CXC chemokines in pulmonary fibrosis
... review series vascular remodeling are often used interchangeably in the context of both pathological and aberrant angiogenesis, as they are here. Although inflammation and angiogenesis are distinct and separa- ble ...
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The role of chemokines/chemokine receptors in labour
... of inflammation in response to chemokines 139 , which act through seven-‐transmembrane domain G protein-‐coupled receptors termed chemokine ...CC chemokines mainly interact with lymphocytes, ...
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Inflammatory chemokines and metastasis – tracing the accessory
... Inflammatory chemokines and metastasis – tracing the accessory Borsig, L ; Wolf, Monika Julia ; Roblek, Marko ; Lorentzen, A ; Heikenwalder, Mathias Abstract: The tumor microenvironment consists of stromal cells ...
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Cytokines and chemokines in the pathogenesis of low back pain
... Outer IVD injury is seen to induce local inflammation, with increased tissue expression of cytokines, up-regulated activity of MMPs (Antoniou et al., 1996a; Kang et al., 1996) and the promotion of scar tissue ...
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The value of blood cytokines and chemokines in assessing COPD
... understood, inflammation is thought to play a key role. This study is one of largest multiplex investigations of cytokines and chemokine biomarkers to date and is one of the few that includes two large, ...
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Chemokines and asthma: redundancy of function or a coordinated effort?
... of inflammation. Chemokines have been primarily divided into 2 main subfamilies, CXC (α) and CC (β), based upon their sequence homology and the position of the first 2 cysteine residues ...novel ...
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The Role of Chemokines in the Pathophysiology of Major Depressive Disorder
... chronic inflammation and MDD, which is manifested by increased levels of the C-reactive protein, as well as pro-inflammatory cytokines, such as Interleukin 1 beta, Interleukin 6, and the Tumor necrosis factor ...
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Fractalkine and other chemokines in primary biliary cirrhosis
... modulate inflammation in the BEC of PBC, thus suggesting that novel therapies to block fractalkine induced environment may prove ...Th1 chemokines produced by BEC stimulated ...
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Citrullination and proteolytic processing of chemokines by Porphyromonas gingivalis
... Kgp). Chemokines attract leukocytes during ...of chemokines by proteases or human peptidylarginine deimi- nases may alter their biological ...of chemokines by ...
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Involvement of β-chemokines in the development of inflammatory demyelination
... EAE is a valuable model for studying the effector arm of immune response in inflammatory demyelination. It can be induced in susceptible strains of inbred and outbred species by active immunization with myelin related ...
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Role of Cytokines and Chemokines in Alcohol-Induced Tumor Promotion
... NF-κ B-TNF-α signaling pathway TNF- α is involved in multiple signaling pathways and can activate NF- κ B which, in turn, also participates in regulating TNF- α. 70 LPS-induced oxidative stress activates NF- κ B, ...
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