chloride channels
ClC chloride channels
... ClC channels, and it is clear that at least one family member acts ...ClC-0 chloride channels can be reconstituted from electric ray (Torpedo) electric organ membranes into planar lipid ...forms ...
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Stilbene derivatives inhibit the activity of the inner mitochondrial membrane chloride channels
... ion channels in the mitochondrial membranes are a popular subject of research due to their involvement in the regulation of cellular life/death ...potassium channels in the inner mitochondrial membrane are ...
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Pharmacology of skeletal muscle GABA gated chloride channels in the cockroach Periplaneta americana
... GABA-gated chloride channels. Thus, muscle GABA-gated chloride channels may be of significance in the toxic actions of these ...GABA-gated chloride channels, differences are ...
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Some properties of GABA-activated chloride channels in mammalian neurones
... spinal cord (e.g. Curtis, Phillis & Watkins, 1961), including locust muscle (e.g. Cull-Candy 1984), lobster stretch receptor neurones (Adams, Constanti & Banks 1981) and mammalian ganglionic (Adams & Brown ...
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Tamoxifen blocks chloride channels A possible mechanism for cataract formation
... cataract. Chloride channels in the lens of the eye were shown to be essential for maintaining normal lens hydration and ...These channels were blocked by tamoxifen and, in organ culture, tamoxifen ...
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Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels
... CLC-3 chloride channels are members of an extended family of voltage-dependent chloride channels and trans- porters, with multiple functional properties and subcel- lular locations [28, ...
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Functional modifications of acid-sensing ion channels by ligand-gated chloride channels
... Glycine receptors are ligand-gated chloride channels that are abundantly expressed in spinal neurons [15]. To determine if activation of glycine receptors modifies ASICs, we recorded ASIC currents from ...
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Short Communication Single channel Recordings from Insect Neuronalgaba activated Chloride Channels
... 1987 have used noise analysis to estimate that the conductance of chloride channels activated by GABA 5.0xlO~ 5 moll~ 1 on cultured embryonic cockroach Periplaneta americana brain neuro[r] ...
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High glucose inhibits ClC-2 chloride channels and attenuates cell migration of rat keratinocytes<div><br /></div>
... Background: Accumulating evidence has demonstrated that migration of keratinocytes is critical to wound epithelialization, and defects of this function result in chronic delayed-healing wounds in diabetes mellitus ...
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Antiviral Drugs from the Nucleoside Analog Family Block Volume-Activated Chloride Channels
... AZT and acyclovir block the swelling-induced chloride current and regulatory volume decrease (RVD) in the human T cell lymphoma cell line H9.. (a) In H9 cells (puilse protocol see Fig. l[r] ...
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Chloride channels in apical membrane patches of stellate cells of Malpighian tubules of Aedes aegypti
... − channels share the same halide selectivity sequence, the type I Cl − channels may be part of the transepithelial pathway taken by Cl − under control ...of channels, we are not aware of ion ...
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Chloride channels in the eel intestine
... values measured directly using double-barrelled Cl − microelectrodes: 27.4 mmol l −1 in isolated frog (Rana temporaria) epidermis (Giraldez and Ferreira, 1984), 22.5 mmol l −1 in toad (Bufo bufo) skin epithelium ...
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Swelling activated chloride channels in leech Retzius neurons
... membrane channels (Ellory and Hall, 1988; Okada, ...ion channels, both cations and anions have to move across the cell membrane in order to satisfy the law of electroneutrality, which implies that the ...
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Volume regulation in the bovine lens and cataract The involvement of chloride channels
... Single-cell studies. Single isolated fiber cells, obtained from the most superficial cortical region of the posterior lens, were recorded from using the whole-cell patch-clamp technique with NMDG-Cl in the pipette to ...
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Chloride channels of intracellular organelles and their potential role in cystic fibrosis
... If CFTR is the chloride channel or a closely associated protein, then we would expect the trans Golgi and other vesicles to contain CFTR in normal cells and their acidification should be[r] ...
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A Novel Role of Chloride Channels in Cerebellar Ataxia
... Cerebellar ataxias are characterized by a disturbance of motor coordination and learning. To understand the molecular mechanisms underlying especially hereditary cerebellar ataxias, many mouse models, often with altered ...
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Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea
... Several observations support the conclusion that ErbB TKI–induced diarrhea involves amplification of basolateral K + and apical CFTR Cl – channel function in intestinal epithelial cel[r] ...
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Physiology of rat retinal pericytes: modulation of ion channel activity by serum derived molecules
... ion channels play a vital role in cellular function, we examined the effect of blood-derived molecules on the ionic currents of retinal ...ion channels, including non-specific cation, outward potassium and ...
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Quantized Three-Ion-Channel Neuron Model for Neural Action Potentials
... Multiple mathematical models have been pro- duced recently in an attempt to condense the main features of brain neurons, as well as in an effort to extend this to the quantum realm [22, 23, 24, 25, 26, 27]. Furthermore, ...
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Isolation, molecular characterization and phylogenetic analysis of potential phosphate solubility bacteria from Oryza sativa
... Uptake and translocation of cationic and anionic nutrients play essential roles in physiological processes including plant growth, nutrition, signal transduction, and development. Approximately 5% of the Oryza sativa ...
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