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Studies on the anti bacterial and anti fungal activities of plant safed musli (Chlorophytum Borivilianum)

... of Chlorophytum borivilianum, ...C. borivilianum is cultivated on large scale in many parts of the county because it produces the highest yield and highest saponin content and used as Safed ...

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PROSPECTS OF USING MS FOR IN VITRO PROPAGATION OF CHLOROPHYTUM BORIVILIANUM

... care. Chlorophytum borivilianum is such a better option in the current context which can be taken up as a medicinal and nutritional diet in the form of powders and chips ...etc. Chlorophytum ...

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BIOCHEMICAL CHANGES DURING SHOOT DIFFERENTIATION IN CALLUS CULTURES OF CHLOROPHYTUM BORIVILIANUM SANT. ET FERNAND

... Biochemical changes leading to shoot regeneration during in vitro culture of callus derived from bud pedicel of Chlorophytum borivilianum on MS medium (Murashige and Skoog, 1962) supplemented with 1.0 mg/l ...

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ANTI-INFLAMMATORY POTENTIAL OF CHLOROPHYTUM BORIVILIANUM SANT. & FERN. ROOT TUBERS Panda S.K.

... The methanolic extract of Chlorophytum borivilianum Sant.& Fern. root tubers (MECB) (200 & 400mg / Kg b.w., p.o.) were tested in Carrageenan induced rat paw edema and cotton pellet induced ...

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Influence of plant morphology on root yield in Safed Musli (Chlorophytum borivilianum) to identify morphological marker traits

... of Chlorophytum borivilianum were characterized for 4 morphological features (plant architecture, flowering nature, leaf margin and canopy shape), 7 yield attributing traits (canopy spread, leaf width, leaf ...

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Morphometrical Study of Seminiferous Tubules of Mice After Using Arsenic and Chlorophytum Borivilianum.

... Chlorophytum borivilianum a medicinal plant belonging to family liliaceae has been traditionally used as adaptogenic ...C. borivilianum root is aphrodisiac, adaptogen, antiageing, health restorative ...

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Chlorophytum borivilianum (Safed Musli) root extract prevents impairment in characteristics and elevation of oxidative stress in sperm of streptozotocin induced adult male diabetic Wistar rats

... or Chlorophytum borivilianum (family: Lilliaceae) is a highly valued medicinal plant in India and is considered as “white gold” in Indian system of Ayurveda ...C. borivilianum root has been used to ...

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PLANT REGENERATION THROUGH ORGANOGENESIS FROM YOUNG LEAVES OF CHLOROPHYTUM BORIVILIANUM

... Dave, A., Joshi, N. and Purohit, S.D. (2004). In vitro propagation of Chlorophytum borivilianum using encapsulated shoot buds. Euro J. Hort. Sci. 69: 37-42. Kirtikar, K.R. and Basu, B.D. (1975). Liliaceae, ...

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A STUDY OF HYPOCHOLESTEREMIC EFFECTS OF CHLOROPHYTUM BORIVILIANUM TUBERS IN RATS

... aphrodisiac as well as immunomodulatory activity 1 . Tubers of this plant used to treat oligospermia, pre and post natal symptoms, arthritis, diabetes and dysuria 2, 3 . It is very good tonic to increase physical and ...

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PHARMACOGNOSTICAL STUDIES OF POTENTIAL HERB CHLOROPHYTUM BORIVILIANUM

... The plant is rich in many pharmaceutical active constituents, mainly glycoside which has been isolated from leaves 5 and roots 6 . In view of its diverse medicinal applications, and in order to ensure complete quality of ...

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HIGH FREQUENCY DIRECT SOMATIC EMBRYOGENESIS FROM THE JUVENILE SHOOT BUDS OF CHLOROPHYTUM BORIVILIANUM SANT ET FERNAND AND PRODUCTION OF ARTIFICIAL SEEDS

... CONCLUSIONS: The present paper therefore reports a high frequency of direct somatic embryogenesis from the young shoot buds of Chlorophytum borivilianum. Regeneration through direct somatic embryogenesis ...

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Title: ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CHLOROPHYTUM BORIVILIUANUM (SAFED MUSLI) Author: Hemlata Rathore, Bhushan Hatwar & Shishupal Bodhankar Keyword: Chlorophytum boriviliuanum, Antidiabetic & AntioxidantPage No: 37-43DOI: 10.30876/JOHR.8.3.2019.37-43Abstract: Objective: To investigate the antidiabetic effect of aqueous extract of Chlorophytum borivilianum (safed musli) root. Methods: The collected roots were washed; shade dried and was pulverized with a me chanical pulverizer for the size reduction. It was then passed through mesh of size # 60 and the fine powder was collected and was used for the experiment for powder microscopy and preparation of extract. The root powder (1000 g) was subjected to cold maceration in 2 L of sterile distilled water for 48 hours at room temperature, filtered into a clean round bottom flask. The a- Glucosidase inhibitory activity was conducted where 100µl of a sample of different concentrations was incubated with 50µl a-glucosidase (1.0 U/ml) (from Saccharomyces cerevisiae) in phosphate buffer (0.1 M, pH 6.8) for 10 min at 37°C. The reaction was initiated by addition of 50 µl of substrate: 5 mM, p-nitrophenyl-a-D glucopyranoside in a 0.1 M phosphate buffer at pH 6.8. P-nitrophenol’s release kinetics. The a -Amylase Inhibition where 250µL of the extract (5mg/mL) was preincubated with 250µL of -amylase solution for 10min at 25°C in one set of tubes. In another set of tubes -amylase was preincubated with 250µL of phosphate buffer (pH 6.9). 250µL of starch solution at increasing concentrations (0.30–5.0mg/mL) was added to both sets of reaction mixtures to start the reaction. The mixture was then incubated for 10min at 25°C and then boiled for 5min after the addition of 500µL of DNS to stop the reaction. Results: In this study acarbose was also used as a standard drug for a-glucosidase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 30. 31±0.1084to 84.05±0.2075% with an IC value 411.436567µg dry extract, & acarbose was also used as a standard drug for a amylase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 23.33±0.1415 to 62.05±0.2725% with an IC value 236.774194µg dry extract. Conclusions: As a result, we found that the extract of C. boriviliamum have free radical scavenging activity and inhibitory activity against a-amylase and a-glucosidase and this therapeutic potentiality could be exploited in the management of post prandial hyperglycemia in the treatment of type 2 diabetes mellitus. Download PDF

... [11]. Chlorophytum borivilianum, commonly known as Safed Musli, is a highly valued medicinal plant in India and Southeast ...C. borivilianum could induce acute reduction of blood glucose levels in ...

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In vitro propagation of Chlorophytum borivilianum (Safed musli) through mature explant

... The basic nutrient medium Murashige and Skoog (1962) supplemented with different concentrations of growth hormones were used for the micropropagation of Chlorophytum borivilianum. The pH of the medium was ...

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Screening of Antistress Properties of Chlorophytum Borivilianum Tuber

... Chlorophytum borivilianum belonging to family liliaceae is a very famous for its adaptogenic, immunomodulatory properties in traditional Indian system of ...

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Title: ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CHLOROPHYTUM BORIVILIUANUM (SAFED MUSLI) Author: Hemlata Rathore, Bhushan Hatwar & Shishupal Bodhankar Keyword: Chlorophytum boriviliuanum, Antidiabetic & AntioxidantPage No: 37-43DOI: 10.30876/JOHR.8.3.2019.37-43Abstract: Objective: To investigate the antidiabetic effect of aqueous extract of Chlorophytum borivilianum (safed musli) root. Methods: The collected roots were washed; shade dried and was pulverized with a me chanical pulverizer for the size reduction. It was then passed through mesh of size # 60 and the fine powder was collected and was used for the experiment for powder microscopy and preparation of extract. The root powder (1000 g) was subjected to cold maceration in 2 L of sterile distilled water for 48 hours at room temperature, filtered into a clean round bottom flask. The a- Glucosidase inhibitory activity was conducted where 100µl of a sample of different concentrations was incubated with 50µl a-glucosidase (1.0 U/ml) (from Saccharomyces cerevisiae) in phosphate buffer (0.1 M, pH 6.8) for 10 min at 37°C. The reaction was initiated by addition of 50 µl of substrate: 5 mM, p-nitrophenyl-a-D glucopyranoside in a 0.1 M phosphate buffer at pH 6.8. P-nitrophenol’s release kinetics. The a -Amylase Inhibition where 250µL of the extract (5mg/mL) was preincubated with 250µL of -amylase solution for 10min at 25°C in one set of tubes. In another set of tubes -amylase was preincubated with 250µL of phosphate buffer (pH 6.9). 250µL of starch solution at increasing concentrations (0.30–5.0mg/mL) was added to both sets of reaction mixtures to start the reaction. The mixture was then incubated for 10min at 25°C and then boiled for 5min after the addition of 500µL of DNS to stop the reaction. Results: In this study acarbose was also used as a standard drug for a-glucosidase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 30. 31±0.1084to 84.05±0.2075% with an IC value 411.436567µg dry extract, & acarbose was also used as a standard drug for a amylase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 23.33±0.1415 to 62.05±0.2725% with an IC value 236.774194µg dry extract. Conclusions: As a result, we found that the extract of C. boriviliamum have free radical scavenging activity and inhibitory activity against a-amylase and a-glucosidase and this therapeutic potentiality could be exploited in the management of post prandial hyperglycemia in the treatment of type 2 diabetes mellitus. Download PDF

... In-vitro Antioxidant Activity DPPH 2, 2- Diphenyl-1-Picrylhydrazyl Radical Scavenging Method: Free radical scavenging activity of the petroleum ether, acetone, chloroform, methanolic and[r] ...

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Title: ANTIDIABETIC AND ANTIOXIDANT ACTIVITY OF AQUEOUS ROOT EXTRACT OF CHLOROPHYTUM BORIVILIUANUM (SAFED MUSLI) Author: Hemlata Rathore, Bhushan Hatwar & Shishupal Bodhankar Keyword: Chlorophytum boriviliuanum, Antidiabetic & AntioxidantPage No: 37-43DOI: 10.30876/JOHR.8.3.2019.37-43Abstract: Objective: To investigate the antidiabetic effect of aqueous extract of Chlorophytum borivilianum (safed musli) root. Methods: The collected roots were washed; shade dried and was pulverized with a me chanical pulverizer for the size reduction. It was then passed through mesh of size # 60 and the fine powder was collected and was used for the experiment for powder microscopy and preparation of extract. The root powder (1000 g) was subjected to cold maceration in 2 L of sterile distilled water for 48 hours at room temperature, filtered into a clean round bottom flask. The a- Glucosidase inhibitory activity was conducted where 100µl of a sample of different concentrations was incubated with 50µl a-glucosidase (1.0 U/ml) (from Saccharomyces cerevisiae) in phosphate buffer (0.1 M, pH 6.8) for 10 min at 37°C. The reaction was initiated by addition of 50 µl of substrate: 5 mM, p-nitrophenyl-a-D glucopyranoside in a 0.1 M phosphate buffer at pH 6.8. P-nitrophenol’s release kinetics. The a -Amylase Inhibition where 250µL of the extract (5mg/mL) was preincubated with 250µL of -amylase solution for 10min at 25°C in one set of tubes. In another set of tubes -amylase was preincubated with 250µL of phosphate buffer (pH 6.9). 250µL of starch solution at increasing concentrations (0.30–5.0mg/mL) was added to both sets of reaction mixtures to start the reaction. The mixture was then incubated for 10min at 25°C and then boiled for 5min after the addition of 500µL of DNS to stop the reaction. Results: In this study acarbose was also used as a standard drug for a-glucosidase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 30. 31±0.1084to 84.05±0.2075% with an IC value 411.436567µg dry extract, & acarbose was also used as a standard drug for a amylase inhibitor. Acarbose at a concentration of (100-1000 µg/ml) showed a-glucosidase inhibitory activity from 23.33±0.1415 to 62.05±0.2725% with an IC value 236.774194µg dry extract. Conclusions: As a result, we found that the extract of C. boriviliamum have free radical scavenging activity and inhibitory activity against a-amylase and a-glucosidase and this therapeutic potentiality could be exploited in the management of post prandial hyperglycemia in the treatment of type 2 diabetes mellitus. Download PDF

... Some of the common disorders of the liver include cirrhosis, viral hepatitis, alcoholic liver disease, hemochromatosis, and liver cancer.. 1 Cirrhosis is a widespread and progressive chr[r] ...

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Plantlet Regeneration from Auxillary Bud of Chlorophytum Tuberosum

Chlorophytum borivilianum