Cholangiocarcinoma Cells
Original Article Biological effects of RNAi targeted inhibiting Tiam1 gene expression on cholangiocarcinoma cells
... differentiated cholangiocarcinoma tissues was significantly higher than that in high/moderately differ- entiated ...in cholangiocarcinoma tissues of stage III and IV was significantly higher than that in ...
16
Inhibition of PI3K increases oxaliplatin sensitivity in cholangiocarcinoma cells
... cer cells with RAD001 can increase their sensitivity to cis- platin ...of cholangiocarcinoma cells with ...apoptotic cells and the activation of caspase-3 did not significantly increase when ...
8
Original Article miR-21 regulates proliferation and invasion of hilar cholangiocarcinoma cells
... hilar cholangiocarcinoma and normal ...hilar cholangiocarcinoma and explore potential ...hilar cholangiocarcinoma cells via regulating PTEN ...
6
Sulfated galactans from red seaweed Gracilaria fisheri target epidermal growth factor receptor (EGFR) and inhibit cholangiocarcinoma cells (CCA) proliferation
... Sulfated Galactans from Red Seaweed Gracilaria fisheri Target Epidermal Growth Factor Receptor EGFR and Inhibit Cholangiocarcinoma Cells CCA Proliferation.. Thannicha Sae-lao Department [r] ...
24
Preclinical evaluation of sorafenib-eluting stent for suppression of human cholangiocarcinoma cells
... in cholangiocarcinoma cells (Figure ...cancer cells, ie, invasion of HuCC-T1 cells was inhibited by treatment with sorafenib, and the released sorafenib from the PCL film also effectively ...
15
The synergistic antitumor effect of Huaier combined with 5 Florouracil in human cholangiocarcinoma cells
... Our study verified that Huaier could inhibit the proliferation of cholangiocarcinoma cells in a concen- tration range of 1.5 to 24 mg/ml. Concentration- dependent and time-dependent manner were also ob- ...
12
Defensive mechanism in cholangiocarcinoma cells against oxidative stress induced by chlorin e6-based photodynamic therapy
... SNU1196 cells could be due to varying intracellular levels of GSH and its ability to reduce antioxidants, despite similar levels of intracellular ROS generation (Figures 2 through ...
12
Original Article Effects of aconitine on the proliferation and apoptosis of human cholangiocarcinoma cells
... 939 cells. A-D: QBC-939 cells were incubated with aconitine at various con- centrations of 0, 1, 10 and 100 ...939 cells apoptosis rate after exposure to aconi- tine at concentrations of 1~100 μM for ...
6
<p>Diosgenin Suppresses Cholangiocarcinoma Cells Via Inducing Cell Cycle Arrest And Mitochondria-Mediated Apoptosis</p>
... We built the xenograft tumor model of HuCCT1 cells. The body weight of mice showed no remarkable changes (Figure 5A), while tumor weights and volumes decreased apparently (Figure 5D and E). To verify the ...
12
Increased ETV4 expression correlates with estrogen-enhanced proliferation and invasiveness of cholangiocarcinoma cells
... Transfection with a shRNA plasmid against ETV4 (shETV4) and carrying GFP was carried out in accord- ance with manufacturer’s instructions. The best strands of shETV4 for each cell line were selected by real time PCR, ...
13
FBXW7 suppresses epithelial-mesenchymal transition, stemness and metastatic potential of cholangiocarcinoma cells
... demonstrated that mTOR inhibitor, combined with other antitumor agents or not, could inhibit the development of CCA [28, 29, 34, 35]. ZEB1 silencing, either chemically or by RNAi, in mesenchymal-like cells results ...
16
<p>Expression of endoplasmic reticulum oxidoreductase 1-α in cholangiocarcinoma tissues and its effects on the proliferation and migration of cholangiocarcinoma cells</p>
... Human cholangiocarcinoma cell line CCKS1 was pro- vided by the Department of Human Pathology at Kanazawa University, 16 and it was approved by Ethics Committee of Kanazawa ...epithelial cells HIBepiC were ...
13
Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells
... HuCC-T1 cells while growth of HEK293T cells was not ...HEK293T cells while it sup- pressed the viability of HuCC-T1 cells in a cytotoxicity ...HuCC-T1 cells with 5 µ g/mL EGCG (Figure ...
8
Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents
... Cholangiocarcinoma (CCA) is an extremely aggressive malignant tumor of the bile duct that becomes one of the major health problems worldwide. It is originating from the epithelial cells of the extrahepatic ...
13
Original Article Effects of norcantharidin on histochemistry and ultra-microstructure of cholangiocarcinoma RBE cells
... of cholangiocarcinoma is low, and there are no standard chemotherapeutic ...blood cells [6], NCTD has continuously gained more ...of cholangiocarcinoma cells, and discussed the mechanism with ...
6
Hepatitis C virus infection and the risk of intrahepatic cholangiocarcinoma and extrahepatic cholangiocarcinoma: evidence from a systematic review and meta analysis of 16 case control studies
... The mechanism of CCA development in patients with HCV infection has not yet been clarified in detail. One study suggests that the presence of HCV in the bile duct epithelium indicates that HCV infection can cause chronic ...
8
Involvement of Wnt/β-catenin signaling in the mesenchymal stem cells promote metastatic growth and chemoresistance of cholangiocarcinoma
... of cholangiocarcinoma xenograft tumors, and conditioned media from hUC-MSCs inhibited proliferation and induced apoptosis of tumor cells in a dose- and time-dependent manner ...human ...
14
M3 muscarinic acetylcholine receptors regulate epithelial–mesenchymal transition, perineural invasion, and migration/metastasis in cholangiocarcinoma through the AKT pathway
... of cholangiocarcinoma cells, we used an ex vivo DRG ...RBE cells, the cells appear to invade the DRG and the surrounding nerve fibers ...RBE cells invading the DRG and surrounding nerve ...
12
Original Article MiR-221 affects cholangiocarcinoma cell proliferation and apoptosis by targeting the SOCS3/JAK-STAT signaling pathway
... HEK293T cells but not in pMIR-SOCS3- mut transfected HEK293T cells, indicating that there is a targeted regulatory relationship bet- ween miR-221 and SOCS3 ...of cholangiocarcinoma through reduc- ing ...
8
How Grim is Cholangiocarcinoma?
... Liver function tests are useful in defining the degree of obstructive jaundice and as a baseline for follow-up. Elevated alkaline phosphatase (ALP) and gamma- glutamyltransferase (GGT) may be an early isolated ...
7