cholesterol ester transfer protein
The levels of plasma low density lipoprotein are independent of cholesterol ester transfer protein in fish-oil fed F1B hamsters
... reverse cholesterol transport pathway, which removes cholesterol from peripheral tissues and returns to the ...liver. Cholesterol ester transfer protein (CETP) plays a major role ...
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Sterol upregulation of human CETP expression in vitro and in transgenic mice by an LXR element
... The cholesterol ester transfer protein (CETP) facilitates the transfer of HDL cholesterol esters from plasma to the ...of cholesterol into bile acids in the liver, is also ...
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Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents
... enzyme cholesterol ester transfer protein (CETP) [28] leading to an increase in the exchange of cholesterol ester and triglyceride be- tween TRL and ...
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Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver
... In this work we showed that some important changes in lipoprotein profile responses to ciprofibrate treatment are largely dependent on the baseline genotype-phenotype, specifically on the high levels of apoCIII and CETP. ...
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I405V and -629C/A Polymorphisms of the Cholesteryl Ester Transfer Protein Gene in Patients with Coronary Artery Disease
... cellular cholesterol removal could be involved in the apparent cardio protective role of CETP gene variation that relates to higher expression of this lipid transfer protein ...lipid transfer ...
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Serum CETP status is independently associated with reduction rates in LDL-C in pitavastatin-treated diabetic patients and possible involvement of LXR in its association
... Cholesteryl ester transfer protein (CETP) is a 74-kDa glycoprotein that is synthesized in liver and adipose tis- sues and subsequently secreted into the bloodstream ...the cholesterol ...
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Alcohol consumption, TaqIB polymorphism of cholesteryl ester transfer protein, high-density lipoprotein cholesterol, and risk of coronary heart disease in men and women
... Plasma lipids assessed using standard methods with reagents from Roche Diagnostics (Indianapolis, IN, USA) and Genzyme (Cambridge, MA, USA) included triglycerides, total cholesterol, HDL-C, and directly obtained ...
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Cholesteryl ester transfer-protein modulator and inhibitors and their potential for the treatment of cardiovascular diseases
... the transfer functions of CETP and achieves a favorable plasma-lipids profile as well as a marked increase in HDL cholesterol and decrease in LDL ...HDL cholesterol in vivo using a hamster model, ...
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Association of Cholesteryl Ester Transfer Protein Gene Taqib Polymorphism and the Associated Phenotype Variation with Coronary Artery Disease.
... coronary primary prevention trial, the Helsenki Heart study, have been conducted to examine the role of risk factors for coronary artery disease. The risk factors identified by these epidemiological studies include a ...
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CETP gene polymorphisms and risk of coronary atherosclerosis in a Chinese population
... lipoprotein cholesterol (HDL-C) has causal role in the pathogenesis and development of coronary ...Cholesteryl ester transfer protein (CETP) is an important regulator of plasma ...
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Increased catabolic rate of low density lipoproteins in humans with cholesteryl ester transfer protein deficiency
... decreased LDL cholesterol and apolipoprotein B levels. The present study was undertaken to elucidate the metabolic basis for the decreased LDL cholesterol and apo B levels in CETP deficiency. We conducted a ...
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Cholesterol efflux potential of sera from mice expressing human cholesteryl ester transfer protein and/or human apolipoprotein AI
... for cholesterol released in 4 h from Fu5AH donor cells to 5% sera from the different groups of mice were in the order: background = human apo AI transgenic (HuAITg) > human CETP transgenic (HuCETPTg) > human ...
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Distribution and concentration of cholesteryl ester transfer protein in plasma of normolipemic subjects
... concomitantly decreased. With high detergent concentration (0.5% Triton), the interference is eliminated and a specific RIA in which all plasma CETP fractions have the same affinity can be obtained. Plasma levels of ...
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Impact of high-density lipoprotein 3 cholesterol subfraction on periprocedural myocardial injury in patients who underwent elective percutaneous coronary intervention
... lipoprotein cholesterol (HDL-C) has a strong inverse relationship with cardiovascular disease (CVD) and is an independent predictor of CVD ...cholesteryl ester transfer protein (CETP) ...
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... Cholesteryl ester transfer protein (CETP) is a crucial protein in high-density lipoprotein cholesterol (HDL-C) ...cholesteryl ester transfer protein medi- ates the ...
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Anacetrapib: potential for the prevention and treatment of coronary heart disease
... lipoprotein cholesterol (LDL-C) reduction, other lipid risk factors, such as low high-density lipoprotein cholesterol (HDL-C), have created interest as therapeutic targets to lower cardiovascular ...
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A Molecular and Biochemical Study for Cholesteryl Ester Transfer Protein (CETP) Taq1B in Iraqi Patients with Hyperlipidemia
... Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a hydrophobic plasma glycoprotein that reduces the time required for transferring esterified ...
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Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice
... reverse cholesterol trans- port, and exerting anti-oxidative, anti-inflammatory, anti-thrombotic and vasodilatory activities ...cholesteryl ester transfer protein (CETP) inhibitors, had failed ...
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Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
... total cholesterol, TG, and apo B, apo A-I, and apo E ...Total cholesterol and TG were not affected by anacetrapib monotherapy or with concomitant administration with ...C-reactive protein reduction ...
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Hyperalphalipoproteinemia in human lecithin cholesterol acyltransferase transgenic rabbits In vivo apolipoprotein A I catabolism is delayed in a gene dose dependent manner
... of cholesterol, yielding cholesteryl esters and lysolecithin (1, ...free cholesterol by LCAT is essential for the HDL particle maturation process by providing cholesteryl esters for the hydrophobic core, ...
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