cholesterol uptake
Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression
... on cholesterol uptake, curcumin was freshly dissolved in dimethyl sulfoxide (DMSO) at different concentrations and immediately diluted in the DMEM culture medium as described ...the cholesterol ...
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The mechanism whereby bile acid micelles increase the rate of fatty acid and cholesterol uptake into the intestinal mucosal cell
... and cholesterol uptake into the intestinal mucosal ...of uptake (Jd) of several fatty acids and cholesterol was a linear function of the concentration of these molecules in the bulk phase if ...
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The effect of maternal undernutrition on the rat placental transcriptome: protein restriction up regulates cholesterol transport
... of cholesterol transport or measurement of the genes of interest at the level of protein, assumptions are being made about the pro- cesses of cholesterol uptake and efflux being sensitive to maternal ...
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The atypical antipsychotic quetiapine induces hyperlipidemia by activating intestinal PXR signaling
... position of 3-cm distally away from stomach to avoid Brunner’s gland reside. The separated intestine was then flushed twice with DPBS and incubated with cold DPBS on ice for 1 hour. The intestine was cut longi- tudinally ...
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Hepatic Niemann Pick C1–like 1 regulates biliary cholesterol concentration and is a target of ezetimibe
... biliary cholesterol secretion in mice (13, 14) and humans ...lesterol uptake from the canalicular side of a hepatocyte in an animal is technically ...measure cholesterol uptake from the bile ...
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Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster
... ester uptake, extrahepatic tissues accounted for z 24% of total HDL cholesteryl ester turnover in normal ...ester uptake by all extra- hepatic tissues combined exceeded the rate of LDL choles- terol ...
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Regulation of Lipid Homeostasis, Inflammatory Signalling and Atherosclerosis by the Peroxisome Proliferator-Activated Receptor Delta
... peptide sequence (Sun et al., 2005). Under conditions of high intracellular sterols, SCAP also interacts with the insulin induced genes (INSIG) 1/2; ER-anchor proteins that retain the SCAP/SREBP complex in the ER. When ...
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Defective HDL particle uptake in ob/ob hepatocytes causes decreased recycling, degradation, and selective lipid uptake
... HDL cholesterol and apoproteins ...and cholesterol uptake and trafficking have been largely elucidated (5, ...LDL-derived cholesterol to the plasma membrane and endoplasmic reticulum for ...
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Identification of CETP as a molecular target for estrogen positive breast cancer cell death by cholesterol depleting agents
... of cholesterol and binding of CETP to AP by CETSA which may provide insights into the regulation of ...proliferation, cholesterol uptake and survival as silencing CETP reduced cell numbers, ...
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Alginate reduces the increased uptake of cholesterol and glucose in overweight male subjects: a pilot study
... altered uptake kinetics for glucose with consequences for impaired maintenance of blood glucose and ...glucose uptake in the high body-fat group by comparison with the normal body fat ...blood ...
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Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol
... Cholesterol uptake is a pathway by which extracellular modified LDL are ingested by macrophages via receptors- mediated phagocytosis and ...promote cholesterol uptake by increas- ing SRA2 and ...
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SR BI protects against endotoxemia in mice through its roles in glucocorticoid production and hepatic clearance
... to cholesterol delivery through LDL uptake (23), SR-BI–mediated HDL cholesterol uptake appears to be the major source of choles- terol for glucocorticoid synthesis in rodents (20, 24, ...
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Effects of dietary fucoxanthin on cholesterol metabolism in diabetic/obese KK-Ay mice
... total cholesterol levels via the activation of SREBP signaling and by suppressing serum cholesterol uptake in the liver via decreasing LDLR and SR-B1 ...to cholesterol metabolism are specific ...
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β-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins
... reduce uptake of LDL modified by acetylation, in microglia and SRA- or SR-B1- transfected cells ...phospholipid, cholesterol, and cholesteryl ester content as their serum counterparts, and a pro-oxidative ...
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Lipid rafts: linking prion protein to zinc transport and amyloid-β toxicity in Alzheimer's disease
... Zinc is a trace element that is essential for life and whose impor- tance to the function of the central nervous system is increasingly being appreciated. Zinc serves as a cofactor for > 300 enzymes that regulate a ...
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Mechanisms by which saturated triacylglycerols elevate the plasma low density lipoprotein cholesterol concentration in hamsters Differential effects of fatty acid chain length
... and cholesterol interact to alter steady-state plasma LDL- cholesterol ...of cholesterol, there was little effect on receptor-dependent LDL transport but a 36-43% increase in LDL- cholesterol ...
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Deficiency of Glycine N-Methyltransferase Aggravates Atherosclerosis in Apolipoprotein E-Null Mice
... of cholesterol metabolism and inflammation in atherogenesis is not understood ...lipoprotein-mediated cholesterol accumulation in macrophage foam cells by downregulating the ex- pression of reverse ...
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Abnormal high density lipoproteins in cerebrotendinous xanthomatosis
... plasma cholesterol (165 +/- 25 mg/dl) and low density lipoproteins ...HDL- cholesterol reflects a low concentration and an abnormal lipid composition of the plasma ...
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Positively charged cholesterol–recombinant human gelatins foster the cellular uptake of proteins and murine immune reactions
... OR). Cholesterol, hexamethylene diisocyanate, toluene (dry), pyridine (dry), triethylamine (TEA), hexane, dimethylsulfoxide (DMSO) (dehydrated), dichloromethane, 4% paraformaldehyde in phosphate- buffered saline ...
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Metabolism of cholesterol rich chylomicroms Mechanism of binding and uptake of cholesteryl esters by the vascular bed of the perfused rat heart
... The uptake mechanism was nonsaturable and independent of the lipoprotein lipase binding ...receptor-dependent uptake of low density lipoprotein cholesteryl ester by heart endothelium, the chylomicron ...
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