cholesteryl ester
Monoclonal antibody inhibition of cholesteryl ester transfer protein activity in the rabbit Effects on lipoprotein composition and high density lipoprotein cholesteryl ester metabolism
... Cholesteryl ester transfer protein (CETP) promotes in vitro transfer of cholesteryl ester (CE) and triglyceride (TG) between lipoproteins. We studied the function of CETP in vivo in rabbit ...
10
Formation of cholesteryl ester rich particulate lipid during metabolism of chylomicrons
... The metabolism of chylomicrons doubly labeled with cholesterol- 3 H and triglyceride- 14 C was studied in unanesthetized rats which were absorbing a fatty test meal. 10 min after intravenous injection, 80% of chylomicron ...
8
Investigation of the physical properties of cholesteryl ester liquid crystal and the interaction with cells
... [3], cholesteryl ester liquid crystals (CELC) containing cholesteryl moieties may have suitable biological affinity and also enable cell adhesion and proliferation without the need for pre-treatment ...
55
Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib
... cells, cholesteryl ester (CE) and free cholesterol are transported from the cell interior to the small nascent HDL particles by ATP-binding cassette subfamily members G1 and A1, respec- ...
9
Role of platelets in cholesteryl ester formation by U 937 cells
... hypercholesterolemic platelets to support cholesteryl ester synthesis by U-937 cells. Cholesterol-donating activity was also found in a 1,000-g supernatants of activated platelets. These observations point ...
8
Inhibition of cholesteryl ester transfer protein activity by monoclonal antibody Effects on cholesteryl ester formation and neutral lipid mass transfer in human plasma
... 74,000 cholesteryl ester transfer protein (CETP), to investigate the regulation of lecithin:cholesterol acyltransferase (LCAT) activity by cholesteryl ester (CE) transfer, and also to ...
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Molecular organization of the cholesteryl ester droplets in the fatty streaks of human aorta
... Since cholesteryl ester droplets are a major component of fatty streaks, comparison studies were made of the diffraction behavior from pure cholesteryl ...the cholesteryl esters into a ...
12
Accelerated transfer of cholesteryl esters in dyslipidemic plasma Role of cholesteryl ester transfer protein
... in cholesteryl ester mass transfer, compared with normolipidemic ...of cholesteryl esters from HDL to potentially atherogenic apoB-containing lipoproteins in dyslipidemic rabbit and human ...
10
Distribution and concentration of cholesteryl ester transfer protein in plasma of normolipemic subjects
... A MAb (TP-2) directed against human cholesteryl ester transfer protein (CETP) has been applied to the development of a competitive solid-phase RIA. Experiments with immobilized CETP have shown that upon ...
9
Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction
... Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction.. A polymorp[r] ...
9
Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster
... and cholesteryl ester uptake by the various or- gans of the body in ...and cholesteryl ester transport were studied separately as these components of HDL may enter and leave the particle ...
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Association of Cholesteryl Ester Transfer Protein Gene Taqib Polymorphism and the Associated Phenotype Variation with Coronary Artery Disease.
... not cholesteryl ester transfer, suggesting that the binding sites of cholesteryl ester and triglyceride may be ...of cholesteryl ester and triglyceride, possibly together with ...
141
Enzyme deficiency in cholesteryl ester storage disease
... Cholesteryl ester storage disease has been shown to involve severe deficiency of acid cholesteryl ester hydrolase and triglyceride lipase activity in liver, spleen, and lymph node.. The [r] ...
5
Increased catabolic rate of low density lipoproteins in humans with cholesteryl ester transfer protein deficiency
... Increased catabolic rate of low density lipoproteins in humans with cholesteryl ester transfer protein deficiency.. The cholesteryl ester transfer protein CETP transfers lipids among lip[r] ...
10
Compositional mapping of cholesteryl ester droplets in the fatty streaks of human aorta
... We found that for 52% of the clusters the standard deviation of the cluster's droplet melting point distribution was less than half that observed in the surrounding microscopic field.. I[r] ...
12
Biophysical characteristics of cells cultured on cholesteryl ester liquid crystals
... The culturing of human keratinocytes cells on the liquid crystals dramatically increased the lipid moieties in the culture and thus, creating an adhesion layer preferred by cell adhesion[r] ...
7
Accelerated cholesteryl ester transfer in plasma of patients with hypercholesterolemia
... Combining HC d less than 1.063 containing acceptor VLDL + LDL with the d greater than 1.063 fraction from controls containing donor HDL + CE-transfer protein CETP and not the converse co[r] ...
8
Mechanism of plasma cholesteryl ester transfer in hypertriglyceridemia
... To test that CETP concentration limits net CE transfer in conditions of excess Tg-rich acceptor, normolipidemic plasma VLDL Tg = 0.38 mmol/liter, 34 mg/dl and the same plasma enriched wi[r] ...
9
Modulation of VLDL triglyceride metabolism
... CE, cholesteryl ester; CETP, cholesteryl ester transfer protein; FC, free cholesterol; FFA, free fatty acids; LCAT, lecithin:cholesterol acyltransferase; LDLr, LDL receptor; L[r] ...
174
Alterations in lipid transfers to HDL associated with the presence of coronary artery disease in patients with type 2 diabetes mellitus
... This study shows that although lower HDL-cholesterol was not a marker for the presence of CAD in patients with T2DM, the cholesterol transfers to the lipoprotein, both in the esterified and in the non-esterified forms, ...
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