Choroid Plexus
FGF2 is expressed in human and murine embryonic choroid plexus and affects choroid plexus cell behaviour
... onic choroid plexus, we have used embryonic CP cells cul- tured in Matrigel to investigate putative roles of Fgf2 on CPe ...the choroid plexus in ...
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Choroid Plexus Potassium Cotransport: Modulation by Osmotic Stress and External Potassium
... If the Kcotransport efflux pathway is an Na/K/2C1 cotransporter situated on the apical membrane of the choroid plexus, as we have hypothesized Keep et al ., 1994, an increase in efflux f[r] ...
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CT and MR of angiomatous malformations of the choroid plexus in patients with Sturge Weber disease
... Of the eight Sturge-Weber patients that we studied , six showed enlargement and increased enhancement of the choroid plexus on the side affected by the facial nevus and leptomeningeal an[r] ...
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Physiologic Pineal Region, Choroid Plexus, and Dural Calcifications in the First Decade of Life
... calcifications. Choroid calcifications were visi- ble in patients across all age ranges, from younger than 1 month to 10 ...the choroid plexus glomus was calcified in isolation, either unilaterally ...
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Choroid plexus-cerebrospinal fluid route for monocyte-derived macrophages after stroke
... Choroid plexus tissue was diced and re-suspended in a +37 °C papain, neutral protease (dispase II), DNAse (PPD) solution and incubated for 30 min at +37 ...
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Sustained choroid plexus function in human elderly and Alzheimer’s disease patients
... The human choroid plexus (CP), a locus of the blood- CSF barrier (BCSFB), is an organ in the cerebral ventri- cles weighing approximately 2 grams [1]. The CP epithe- lium secretes most of the CSF and helps ...
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High Blood Pressure Effects on the Brain Barriers and Choroid Plexus Secretion
... the choroid plexus (CP) cells and subcommissural organ (SCO) cells and secreted into the CSF [7-9] and the S-100β is synthesized in the astroglial and Swans cells, and when there are alterations in the BBB, ...
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Choroid plexus genes for CSF production and brain homeostasis are altered in Alzheimer’s disease
... Background: The roles of the choroid plexus (CP) and cerebrospinal fluid (CSF) production have drawn increasing attention in Alzheimer’s disease (AD) research. Specifically, studies document markedly ...
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MGMT promoter methylation and temozolomide response in choroid plexus carcinoma
... Abstract Choroid plexus carcinoma (CPC) is a malig- nant tumor with a strong tendency to spread along the cerebrospinal fluid pathway. There is no standardized chemotherapy protocol for this rare tumor. We ...
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Fibroblast growth factor signalling in the development and functions of the choroid plexus
... extraembryonic membranes using curved dissecting scissors. All embryos were transferred into a 10 cm dish of fresh DPBS, with fine forceps. Each embryo was transferred individually into a separate dish of DPBS for ...
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Expression and functional activity of nucleoside transporters in human choroid plexus
... pig choroid plexus involves an organic anion transporting polypeptide 2-like transporter, while its transport across the BBB involves nucleoside transporters ...
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Development of the lateral ventricular choroid plexus in a marsupial, Monodelphis domestica
... Background: Choroid plexus epithelial cells are the site of blood/cerebrospinal fluid (CSF) barrier and regulate molecular transfer between the two ...of plexus epithelium are not known. Methods: ...
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Choroid plexus epithelial monolayers – a cell culture model from porcine brain
... D: Choroid plexus epithelial expression of MDR1 P glycoprotein and multidrug resistance-associated protein contribute to the blood-cerebrospinal-fluid drug- permeability ...
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Culture models to study leukocyte trafficking across the choroid plexus
... porcine choroid plexus epithelial cells (PCPEC) [5,20-23] (an extensive recent review covering BCSFB in vitro models is provided by Strazielle and Ghersi-Egea ...
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Retinoic acid signaling regulates development of the dorsal forebrain midline and the choroid plexus in the chick
... The formation of two cerebral hemispheres from a single telencephalic vesicle in vertebrates begins with the process of invagination in the forebrain roof plate (RP). This process is tightly regulated both spatially and ...
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Choroid Plexus Blood-CSF Barrier: Major Player in Brain Disease Modeling and Neuromedicine
... The choroid plexus (CP) of the blood-cerebrospinal fluid barrier (BCSFB) impacts CSF homeostasis, brain diseases and neuromedical translation. CP executes neuroendocrine, excretory, and neuroimmune actions. ...
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Structural defects in cilia of the choroid plexus, subfornical organ and ventricular ependyma are associated with ventriculomegaly
... There has been a resurgence of interest in the study of higher vertebrates for the role of motile cilia in chemo- sensation or mechanosensation, functions thought to be ascribed solely to primary, immotile cilia [55-58] ...
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The choroid plexus as a site of damage in hemorrhagic and ischemic stroke and its role in responding to injury
... Because of the evidence that the CP can protect the brain from injury, there have been a number of studies exam- ining the effects of CP transplants on different types of brain injury. Borlongan et al. found that ...
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Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus
... The finding that Shh signaling promotes the proliferation of epithelial progenitor cells destined to become part of the hChPe, which is itself a primary source of the Shh ligand, reveals an interesting biological ...
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Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
... primary human brain-derived microvascular endothelial cells (HBMECs) and choroid plexus fibroblasts (labeled as “HCPEpiC”) (characterization of the cells is shown in Additional file 3: Figure S3). We have ...
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