Chromogranin A
Original Article Increased chromogranin A and neuron-specific enolase in rats with chronic nonbacterial prostatitis induced by 17-beta estradiol combined with castration
... Abstract: Although chronic nonbacterial prostatitis (CNBP) is a common diagnosis in middle-aged men, the etiol- ogy of this disease remains poorly understood. Neuroendocrine cells play an important role in the ...
8
Effects of Prolonged Night Shifts on Salivary α Amylase, Secretory Immunoglobulin, Cortisol, and Chromogranin A Levels in Nurses
... cortisol, chromogranin A, α-amylase activity and secretory immunoglobulin A ...in chromogranin A and sIgA levels were detected between day and night shift ...
13
Chromogranin A expression in normal and malignant human tissues
... human chromogranin A to measure the expression of mRNA encoded by this gene in a variety of normal human tissues and tumor specimens using Northern blot and in situ hybridization ...of chromogranin A mRNA ...
6
Catecholamines, cardiac natriuretic peptides and chromogranin A: evolution and physiopathology of a ‘whip brake’ system of the endocrine heart
... Recently, chromogranin A (CgA), a major constituent of the secretory granules, and its derived cardio-suppressive and antiadrenergic peptides, vasostatin- 1 and catestatin, were shown as new players in this ...
23
<p>Chromogranin A is a predictor of prognosis in patients with prostate cancer: a systematic review and meta-analysis</p>
... “ chromogranin A ” OR “ parathyroid secretory protein ” OR “ CHGA ” ) AND ( “ prostate cancer ” OR “ prostatic cancer ” OR “ prostate neoplasm ” OR “ prostatic neoplasm ” ...
12
Novel autocrine feedback control of catecholamine release A discrete chromogranin a fragment is a noncompetitive nicotinic cholinergic antagonist
... the chromogranin A fragments generated in the extracellular space (precipitation to remove secreted small molecules such as catecholamines or ...these chromogranin A fragments (1 mM). Once again, ...
12
Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway
... of chromogranin A localization in the secretory pathway on immunocytochemistry of AtT-20 cells under- or overexpressing prohormone conver- tases ...and chromogranin A from pituitary ...
10
Cell type specific gene expression in the neuroendocrine system A neuroendocrine specific regulatory element in the promoter of chromogranin A, a ubiquitous secretory granule core protein
... protein chromogranin A universally occurs in amine and peptide hormone and neurotransmitter storage granules throughout the neuroendocrine ...the chromogranin A gene, to yield such a widespread yet ...
13
Evaluating blood levels of neuron specific enolase, chromogranin A, and circulating tumor cells as Merkel cell carcinoma biomarkers
... Evaluating blood levels of neuron specific enolase, chromogranin A, and circulating tumor cells as Merkel cell carcinoma biomarkers Maria Rita Gaiser1, Kenneth Daily2, Jochen Hoffmann1, [r] ...
11
Inhibition of chronic lymphocytic leukemia progression by full- length chromogranin A and its N-terminal fragment in mouse models
... circulating chromogranin A (CgA) and its N-terminal fragment (called vasostatin-1, CgA 1-76 ), two neuroendocrine secretory polypeptides that enhance the endothelial barrier function, are present in variable ...
12
Comparison of PCR based detection of chromogranin A mRNA with traditional histological lymph node staging of small intestinal neuroendocrine neoplasia
... in 50μL of water mixed with 50μL of 2X RT mix contain- ing Reverse Transcription Buffer, dNTPs, random primers and Multiscribe Reverse Transcriptase. RT reaction was carried out in a thermal cycler for 10 minutes at 25 ...
6
A functional cyclic AMP response element plays a crucial role in neuroendocrine cell type specific expression of the secretory granule protein chromogranin A
... mouse chromogranin A gene promoter, which showed that the promoter contains both positive and negative domains and that a proximal promoter spanning nucleotides -147 to +42 bp relative to the transcriptional start ...
12
Salivary alpha amylase not chromogranin A reflects sympathetic activity: exercise responses in elite male wheelchair athletes with or without cervical spinal cord injury
... Chromogranin A is stored and co-released with adren- aline and noradrenaline from secretory vesicles within the adrenal medulla and post-ganglionic sympathetic axons [12]. It is also secreted from the ...
9
Incidence of high chromogranin A serum levels in patients with non metastatic prostate adenocarcinoma
... Chromogranin A ELISA Kit is designed for the quan- titative determination of CgA in human plasma (EDTA or heparin). The kit can be used for measuring CgA in the 10 to 500 U/L range. The ELISA kit is a double ...
5
Chromogranin-A Levels and Refractory Bronchospasm in Interstitial Lung Disease:
... Pulmonary neuroendocrine cells (PNEC’s) are distributed throughout the lung [1]. They store and secrete a wide variety of various amines, peptides and chromogranin-A (Cg-A) [2,3]. Hyperplasia of the PNEC’s may be ...
6
Hypertension from targeted ablation of chromogranin A can be rescued by the human ortholog
... CHGA, chromogranin A; Dbh, dopamine β-hydroxylase; DBP, diastolic BP; humanized, mouse allele replaced with the human ortholog; Npy, neuropeptide Y; PRA, plasma renin activity; PRC, plasma renin concen- tration; ...
12
Processing of chromogranin A by plasmin provides a novel mechanism for regulating catecholamine secretion
... Chromogranin A (CgA) is the major soluble protein in the core of catecholamine-storage vesicles and is also distributed widely in secretory vesicles throughout the neuroendocrine system. CgA con- tains the ...
10
Kuttner, Axel Josef (2011): Untersuchung zur Sensitivität des Tumormarkers Chromogranin A im Serum bei Patienten mit neuroendokrinen Tumoren des GastroEnteroPankreatischen Systems. Dissertation, LMU München: Medizinische Fakultät
... Kritisch muss die Arbeit bewertet werden bzgl. des retrospektiven Designs und der Datenanalyse nur anhand von Mittelwerten der Einzelpersonen und damit unzureichender Korrelation mit dem individuellen Krankheitsverlauf - ...
54
Expression of pS2 in prostate cancer correlates with grade and Chromogranin A expression but not with stage
... Endogenous peroxidase in the sections was blocked for 30 minutes with 0.3% H2 02 in methanol. Sections were washed with PBS. All sections were treated with Normal Swine serum (NSS) prediluted 1:10 in PBS for 5 minutes. ...
5
Black tea aroma inhibited increase of salivary chromogranin-A after arithmetic tasks
... Chromogranin-A (CgA) is a major protein in the adrenal chromaffin cells and adrenergic neurons. As an ANS activ- ity response to stress, CgA and catecholamines are co- released into the extra-cellular environment. ...
6