chronic hypoxia
Hypoxia-induced mitogenic factor (HIMF/FIZZ1/RELMα) in chronic hypoxia- and antigen-mediated pulmonary vascular remodeling
... both chronic hypoxia and repeated airway antigen challenges induce pulmonary vascular remodeling in adult male C57BL/6 mice; however, differences were apparent in the types and extent of ...to ...
16
Chronic hypoxia stimulates an enhanced response to immune challenge without evidence of an energetic tradeoff
... to chronic hypoxia in several characteristic ways, indicating that they were indeed experiencing hypoxic ...to chronic hypoxia, the exact mechanisms responsible for the change in body mass and ...
14
Epigenetic modifications of chronic hypoxia mediated neurodegeneration in Alzheimer’s disease
... with chronic hypoxia includ- ing obstructive sleep apnea, cerebrovascular diseases, systemic hypertension, cardiovascular disease, chronic obstructive pulmonary disease, pulmonary hypertension, ...
6
Targeting Hif1a rescues cone degeneration and prevents subretinal neovascularization in a model of chronic hypoxia
... a chronic hypoxia-like response, which affects expression of genes involved in cellular me- tabolism and retinal stress, leads to the progressive cone degeneration observed in cone Δ Vhl ...
14
Sympathoadrenal responses to acute and chronic hypoxia in the rat
... and chronic hypoxic exposure at ...exposure. Chronic hypoxia at ...moderate hypoxia at ...moderate hypoxia (2-fold increase in urinary E excretion) and severe hypoxia (greater ...
11
Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia Modulation of gene expression by nitric oxide
... Flt. Chronic hypobaric hypoxia also increased lung tissue mRNA levels of VEGF, KDR/Flk, and Flt and the amount of VEGF ...to hypoxia and that lung VEGF and VEGF receptor mRNA levels are influenced by ...
11
Impact of Chronic Hypoxia on Neurodevelopment of Children with Cyanotic Congenital Heart Disease
... suggest hypoxia may play a significant role in the pathogenesis of malnutrition, growth failure (15,16), and subsequent neurodevelopment ...between chronic hypoxia and their developmental ...
6
Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia inducible factor 1α
... is hypoxia-inducible factor 1 (HIF-1) (16, 17). Among the hypoxia-inducible genes that contain functionally important HIF-1 binding sites are those encoding erythropoietin (16), transferrin (18), vascu- lar ...
7
In situ cardiac function in Atlantic cod (Gadus morhua): effects of acute and chronic hypoxia
... severe hypoxia and ...of hypoxia-acclimated cod following 15min of severe hypoxia was due to an increased ability to protect the myocardium against the negative effects of reactive oxygen species ...
11
Phlebotomy with Iron Therapy to Correct the Microcytic Polycythemia of Chronic Hypoxia
... titration of oral iron replacement (based on changes of red cell indices), and frequent small phlebotomies to prevent rapid rises in hematocrit level. ACKNOWLEDGMENT[r] ...
6
Role of the gap junctions in the contractile response to agonists in pulmonary artery from two rat models of pulmonary hypertension
... to chronic hypoxia for 3 weeks in a hypobaric chamber (50 kPa) and the third group was injected with a single intraperi- toneal dose of monocrotaline (60 ...
13
Phenotypic responses to lifelong hypoxia in cichlids
... blood. At maximal efficiency, all oxygen diffuses from the water into the blood during the water passage between the secondary lamellae. According to Fick’s first law of diffusion, the net gas exchange between water and ...
160
Influence of chronic intrauterine hypoxia on development of testicles of newborns
... of chronic hypoxia on the development of the reproductive glands of the fetus of rats in ...underwent hypoxia throughout the entire pregnancy (21 days). Modeling of hypoxia was carried out in ...
5
Analysis of fifty cases of chronic obstructive lung disease with clinical parameters, ECG and ECHO
... Pulmonary hypertension was the major cardiovascular complication of COPD , the chronic hypoxia of COPD is responsible for the development of pulmonary hypertension .24 percent of the total cases had ...
68
Comparison of nucleated red blood cells in the umbilical cord of term neonates in healthy women and women with preeclampsia
... indicate chronic hypoxia starting a few days prior to delivery ...of chronic hypoxia such as gastrointestinal bleeding, ischemic necrosis of myocardium, hypocalcemia and hypoglycemia, RDS, ...
6
Lung injury and inflammation response by chronic intermittent hypoxia in rats
... that chronic and inter- mittent hypoxia both can result in pulmonary hyperten- sion through inducing pulmonary artery ...of hypoxia/ reoxygenation. Intermittent chronic hypoxia was used ...
7
The effect of Shenmai injection on the proliferation of Rat airway smooth muscle cells in asthma and underlying mechanism
... that chronic hypoxia signifi- cantly increased the mRNA and protein expression of TRPV1 channel in human pulmonary artery smooth muscle cells, leading to an increase in cytosolic Ca 2+ con- centration and ...
10
CYANOTIC HEART DISEASE AND PSYCHOLOGICAL DEVELOPMENT
... effects of chronic hypoxia on the percep- tual, motor, and intellectual development of children with congenital heart disease.. Within the limits of a clinical study, the di-.[r] ...
11
Targeting hypoxic cancer stem cells (CSCs) with Doxycycline : implications for optimizing anti angiogenic therapy
... how chronic hypoxia increases ‘stemness’ in cancer ...the hypoxia-induced propagation of ...of hypoxia-induced CSCs that are Paclitaxel-resistant, overcoming hypoxia-induced ...tumor ...
18
Impact of interleukin-6 on hypoxia-induced pulmonary hypertension and lung inflammation in mice
... to chronic hypoxia is associated with increased lung expres- sion of IL-6R and gp-130 mRNA levels, strongly suggest that IL-6 may act partly as an inducer of PA-SMC migra- tion during chronic ...
13