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Chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia: An immunobiology approach

Chronic lymphocytic leukaemia: An immunobiology approach

... B cell chronic lymphocytic leukaemia (CLL) is the most common adult leukaemia that follows an extremely variable clinical course. Several important prognostic parameters defining pathogenic ...

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CHRONIC LYMPHOCYTIC LEUKAEMIA: AN IMMUNOBIOLOGY APPROACH

CHRONIC LYMPHOCYTIC LEUKAEMIA: AN IMMUNOBIOLOGY APPROACH

... B cell chronic lymphocytic leukaemia (CLL) is the most common adult leukaemia that follows an extremely variable clinical course. Several important prognostic parameters defining pathogenic ...

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Understanding chronic lymphocytic leukaemia (CLL)

Understanding chronic lymphocytic leukaemia (CLL)

... What is chronic lymphocytic leukaemia (CLL)? CLL is a type of leukaemia (cancer of the blood). CLL is usually a slow-growing cancer of lymphocyte white blood cells. The cancer stops the white ...

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Ibrutinib Chronic Lymphocytic Leukaemia & Lymphoma

Ibrutinib Chronic Lymphocytic Leukaemia & Lymphoma

... of chronic lymphocytic leukaemia (CLL) or small lymphocytic leukaemia (SLL) in adults who have a 17p deletion or TP53 mutation (TA429) ...

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Immunotherapy in Chronic Lymphocytic Leukaemia (CLL)

Immunotherapy in Chronic Lymphocytic Leukaemia (CLL)

... Abstract Chronic lymphocytic leukaemia (CLL) is well known to generate impaired immune responses in the host, with the malignant clone residing in well-vascularized tissues and circulating in ...

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The Role of STAT3 in the Pathogenesis of Chronic Lymphocytic Leukaemia

The Role of STAT3 in the Pathogenesis of Chronic Lymphocytic Leukaemia

... The treatment options for chronic lymphocytic leukaemia patients with relapsed or unfavourable prognostic markers have greatly improved over the past few years. The introduction of two novel targeted ...

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Guidelines for the Management of Chronic Lymphocytic Leukaemia (CLL)

Guidelines for the Management of Chronic Lymphocytic Leukaemia (CLL)

... 2.2 The Haematology NSSG has agreed to continue follow the British Committee for Standards in Haematology (BCSH) Guidelines on the diagnosis and management of chronic lymphocytic leukaemia (2004), of ...

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Guidelines on the diagnosis and management of chronic lymphocytic leukaemia

Guidelines on the diagnosis and management of chronic lymphocytic leukaemia

... Chronic lymphocytic leukaemia presents significant man- agement problems by virtue of the heterogeneity in both the age of presentation, in the natural history of the disease and also the frequency ...

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The duality of macrophage function in Chronic Lymphocytic Leukaemia

The duality of macrophage function in Chronic Lymphocytic Leukaemia

... MANUSCRIPT Chronic Lymphocytic Leukaemia (CLL). Chronic lymphocytic leukaemia is a B cell lineage-derived blood cancer characterised by an accumulation of leukaemic cells within ...

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Guidelines on the diagnosis, investigation and management of Chronic Lymphocytic Leukaemia

Guidelines on the diagnosis, investigation and management of Chronic Lymphocytic Leukaemia

... Introduction The guideline group was selected to be representative of UK based medical experts and patients representatives. Recommendations are based on a review of the literature using Medline/Pubmed searches under the ...

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FLUDARABINE AS FIRST LINE THERAPY FOR CHRONIC LYMPHOCYTIC LEUKAEMIA

FLUDARABINE AS FIRST LINE THERAPY FOR CHRONIC LYMPHOCYTIC LEUKAEMIA

... cell chronic lymphocytic leukaemia patients with sufficient bone marrow reserve and who have not responded to or whose disease has progressed during or after treatment with at least one standard ...

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Therapeutic approaches and drug-resistance in chronic lymphocytic leukaemia

Therapeutic approaches and drug-resistance in chronic lymphocytic leukaemia

... of chronic lymphocytic leukaemia has been revolutionised in recent years, first by the introduction of chemoimmunotherapy regimens and subsequently by the development of drugs, including ibrutinib, ...

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Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series.

Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series.

... Key Words: Lacrimal sac, lymphoma, chronic lymphocytic leukaemia, dacryocystitis, epiphora... 3 Malignant tumours of the lacrimal sac are uncommon with close to 90% of these being of ep[r] ...

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Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells

Ibrutinib induces chromatin reorganisation of chronic lymphocytic leukaemia cells

... Abstract Chronic lymphocytic leukaemia (CLL) is the most common leukaemia in Western ...high-risk chronic lymphocytic leukaemia (CLL), with limited adverse ...

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ESMO GUIDELINES: REAL WORLD CASES CHRONIC LYMPHOCYTIC LEUKAEMIA

ESMO GUIDELINES: REAL WORLD CASES CHRONIC LYMPHOCYTIC LEUKAEMIA

... ESMO GUIDELINES: REAL WORLD CASES CHRONIC LYMPHOCYTIC LEUKAEMIA.. Introduction.[r] ...

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Clinical and Haematological Pattern of Chronic Lymphocytic Leukaemia in Sudanese Patients

Clinical and Haematological Pattern of Chronic Lymphocytic Leukaemia in Sudanese Patients

... Chronic lymphocytic leukemia (CLL) has different clinical and haematological features and varies from patient to ...with chronic lymphocytic leukaemia and their clinical and ...

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The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia

The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia

... In chronic lymphocytic leukaemia (CLL) bone marrow trephine biopsy (BMT) is not required for diagnosis but can have a significant prognostic value and can be used for the detection of the minimal ...

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BHS guidelines for the treatment of chronic lymphocytic leukaemia anno 2012

BHS guidelines for the treatment of chronic lymphocytic leukaemia anno 2012

... The chemotherapy should be given after MabThera infusion. Method of administration: Premedication with glucocorticoids should be considered if MabThera is not given in combination with glucocorticoid-containing ...

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The proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia

The proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia

... ABSTRACT Chronic Lymphocytic Leukaemia (CLL) is the most common adult Leukaemia in the UK, Western Europe and America. It is a malignancy of naïve B-cells. The clinical course of patients with ...

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B-cell chronic lymphocytic leukaemia in an African lion ( Panthera leo

B-cell chronic lymphocytic leukaemia in an African lion ( Panthera leo

... *Corresponding author: [email protected] ABSTRACT: A 15-year-old female African lion (Panthera leo) maintained at the Zoological Garden of Pistoia, Tuscany (Italy), showed signs of malaise, dyspnoea, tremors, pale ...

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